Sex and race differences in QRS duration

J 2016

Sex and race differences in QRS duration

HNATKOVA, Katerina; Peter SMETANA; Ondřej TOMAN; Georg SCHMIDT; Marek MALIK et al.

Základní údaje

Originální název

Sex and race differences in QRS duration

Autoři

HNATKOVA, Katerina; Peter SMETANA; Ondřej TOMAN; Georg SCHMIDT a Marek MALIK

Vydání

Europace, Oxford, Oxford University Press, 2016, 1099-5129

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 4.521

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/16:00094025

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Normal healthy subjects; QRS duration; QRS/RR relationship

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 31. 3. 2017 13:33, Soňa Böhmová

Anotace

V originále

Aims The study investigated healthy subjects to study sex and race differences in QRS durations and the dependency of QRS durations on heart rates and other physiologic correlates. Methods and results QRS duration and its heart rate dependency were evaluated in 420 615 electrocardiograms obtained in 523 healthy subjects including 111 females of African origin, 130 Caucasian females, 125 males of African origin, and 129 Caucasian males. The distributions of QRS/RR slopes and QRS durations at RR intervals of 1 and 0.5 s were compared between sex-and race-defined subgroups. At high heart rates, QRS duration was increased in similar to 35% of all subjects, while in the others, QRS was shortened (no differences between the subgroups). At RR interval of 1 s, the QRS duration was 97.4 +/- 4.6, 99.8 +/- 6.0, 101.6 +/- 5.3, and 104.8 +/- 6.3 ms in African females, Caucasian females, African males, and Caucasian males, respectively (all differences P < 0.001). Similar statistical differences were found at an RR of 0.5 s. When accounting for the differences in lean body mass, the difference between African and Caucasian subjects was as large as the difference between females and males. Within each subgroup, the normal QRS durations differed by 15-20 and 18-25 ms at RR intervals of 1 and 0.5 s, respectively. Conclusion The QRS widths are heart rate dependent and different not only between women and men but also between African and Caucasian individuals. Difference in cardiac resynchronization therapy efficacy might be expected between patients of African and Caucasian origin stratified by QRS duration.

Citovat

HNATKOVA, Katerina; Peter SMETANA; Ondřej TOMAN; Georg SCHMIDT a Marek MALIK. Sex and race differences in QRS duration. Europace. Oxford: Oxford University Press, 2016, roč. 18, č. 12, s. 1842-1849. ISSN 1099-5129. Dostupné z: https://doi.org/10.1093/europace/euw065.

@article{1376746,
   author = {Hnatkova, Katerina and Smetana, Peter and Toman, Ondřej and Schmidt, Georg and Malik, Marek},
   article_location = {Oxford},
   article_number = {12},
   doi = {https://doi.org/10.1093/europace/euw065},
   keywords = {Normal healthy subjects; QRS duration; QRS/RR relationship},
   language = {eng},
   issn = {1099-5129},
   journal = {Europace},
   title = {Sex and race differences in QRS duration},
   volume = {18},
   year = {2016}
}

TY  - JOUR
ID  - 1376746
AU  - Hnatkova, Katerina - Smetana, Peter - Toman, Ondřej - Schmidt, Georg - Malik, Marek
PY  - 2016
TI  - Sex and race differences in QRS duration
JF  - Europace
VL  - 18
IS  - 12
SP  - 1842-1849
EP  - 1842-1849
PB  - Oxford University Press
SN  - 10995129
KW  - Normal healthy subjects
KW  - QRS duration
KW  - QRS/RR relationship
N2  - Aims The study investigated healthy subjects to study sex and race differences in QRS durations and the dependency of QRS durations on heart rates and other physiologic correlates. Methods and results QRS duration and its heart rate dependency were evaluated in 420 615 electrocardiograms obtained in 523 healthy subjects including 111 females of African origin, 130 Caucasian females, 125 males of African origin, and 129 Caucasian males. The distributions of QRS/RR slopes and QRS durations at RR intervals of 1 and 0.5 s were compared between sex-and race-defined subgroups. At high heart rates, QRS duration was increased in similar to 35% of all subjects, while in the others, QRS was shortened (no differences between the subgroups). At RR interval of 1 s, the QRS duration was 97.4 +/- 4.6, 99.8 +/- 6.0, 101.6 +/- 5.3, and 104.8 +/- 6.3 ms in African females, Caucasian females, African males, and Caucasian males, respectively (all differences P < 0.001). Similar statistical differences were found at an RR of 0.5 s. When accounting for the differences in lean body mass, the difference between African and Caucasian subjects was as large as the difference between females and males. Within each subgroup, the normal QRS durations differed by 15-20 and 18-25 ms at RR intervals of 1 and 0.5 s, respectively. Conclusion The QRS widths are heart rate dependent and different not only between women and men but also between African and Caucasian individuals. Difference in cardiac resynchronization therapy efficacy might be expected between patients of African and Caucasian origin stratified by QRS duration.
ER  -

HNATKOVA, Katerina; Peter SMETANA; Ondřej TOMAN; Georg SCHMIDT a Marek MALIK. Sex and race differences in QRS duration. \textit{Europace}. Oxford: Oxford University Press, 2016, roč.~18, č.~12, s.~1842-1849. ISSN~1099-5129. Dostupné z: https://doi.org/10.1093/europace/euw065.

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