A Novel Defibrillation Tool Percutaneously Delivered, Partially
Insulated Epicardial Defibrillation

J 2017

A Novel Defibrillation Tool Percutaneously Delivered, Partially Insulated Epicardial Defibrillation

KILLU, Ammar M; Niyada NAKSUK; Zdeněk STÁREK; Christopher V DESIMONE; Faisal F SYED et al.

Základní údaje

Originální název

A Novel Defibrillation Tool Percutaneously Delivered, Partially Insulated Epicardial Defibrillation

Autoři

Vydání

JACC: Clinical Electrophysiology, New York, Elsevier, 2017, 2405-500X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/17:00096705

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1016/j.jacep.2016.12.025

EID Scopus

2-s2.0-85016514647

Klíčová slova anglicky

arrhythmiadefibrillationepicardialinsulationICDpercutaneous

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 26. 3. 2018 13:11, MUDr. Martin Pešl, Ph.D.

Anotace

V originále

OBJECTIVES We aimed to develop a percutaneous defibrillation system with partially insulated epicardial coils to focus electrical energy on the myocardium and prevent or minimize extracardiac stimulation. BACKGROUND Epicardial defibrillation systems currently require surgical access. METHODS We tested 2 prototypes created for percutaneous introduction into the pericardial space via a steerable sheath. This testing included a partially insulated defibrillation coil and a defibrillation mesh with a urethane balloon acting as an insulator to the face of the mesh not in contact with the epicardium. The average energy associated with a chance of successful defibrillation 75% of the time was calculated for each experiment. RESULTS Of 16 animal experiments, 3 pig experiments had malfunctioning mesh prototypes such that results were unreliable; these were excluded. Therefore, 13 animal experiments were analyzed, 6 in canines (29.8 4.0 kg) and 7 in pigs (41.1 4.4 kg). The overall chance of successful defibrillation 75% of the time was 12.8 6.7 J (10.9 9.1 J for canines and 14.4 3.9 J in pigs; p 0.37). The lowest chance of successful defibrillation 75% of the time obtained in canines was 2.5 J, whereas in pigs it was 9.5 J. The lowest energy resulting in successful defibrillation was 2 J in canines and 5 J in pigs. There was no evidence of coronary vessel injury or trauma to extrapericardial structures. CONCLUSIONS Percutaneous, epicardial defibrillation using a partially insulated coil is feasible and seems to be associated with low defibrillation thresholds. Focusing insulation may limit extracardiac stimulation and potentially lower energy requirements for efficient defibrillation

Návaznosti

LQ1601, projekt VaV

Název: CEITEC 2020 (Akronym: CEITEC2020)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, CEITEC 2020

Přiložené soubory

2017_Killu.pdf

Požádat o autorskou verzi souboru

Citovat

KILLU, Ammar M; Niyada NAKSUK; Zdeněk STÁREK; Christopher V DESIMONE; Faisal F SYED; Prakriti GABA; Jiří WOLF; František LEHAR; Martin PEŠL; Pavel LEINVEBER; Michal CRHA; Dorothy LADEWIG; Joanne POWERS; Scott SUDDENDORF; David O HODGE; Gaurav SATAM; Miroslav NOVÁK; Tomáš KÁRA; Charles J BRUCE; Paul A FRIEDMAN a Samuel J ASIRVATHAM. A Novel Defibrillation Tool Percutaneously Delivered, Partially Insulated Epicardial Defibrillation. JACC: Clinical Electrophysiology. New York: Elsevier, 2017, roč. 3, č. 7, s. 747-755. ISSN 2405-500X. Dostupné z: https://doi.org/10.1016/j.jacep.2016.12.025.

@article{1380782,
   author = {Killu, Ammar M and Naksuk, Niyada and Stárek, Zdeněk and DeSimone, Christopher V and Syed, Faisal F and Gaba, Prakriti and Wolf, Jiří and Lehar, František and Pešl, Martin and Leinveber, Pavel and Crha, Michal and Ladewig, Dorothy and Powers, Joanne and Suddendorf, Scott and Hodge, David O and Satam, Gaurav and Novák, Miroslav and Kára, Tomáš and Bruce, Charles J and Friedman, Paul A and Asirvatham, Samuel J},
   article_location = {New York},
   article_number = {7},
   doi = {https://doi.org/10.1016/j.jacep.2016.12.025},
   keywords = {arrhythmiadefibrillationepicardialinsulationICDpercutaneous},
   language = {eng},
   issn = {2405-500X},
   journal = {JACC: Clinical Electrophysiology},
   title = {A Novel Defibrillation Tool Percutaneously Delivered, Partially Insulated Epicardial Defibrillation},
   url = {http://www.sciencedirect.com/science/article/pii/S2405500X17300919},
   volume = {3},
   year = {2017}
}

TY  - JOUR
ID  - 1380782
AU  - Killu, Ammar M - Naksuk, Niyada - Stárek, Zdeněk - DeSimone, Christopher V - Syed, Faisal F - Gaba, Prakriti - Wolf, Jiří - Lehar, František - Pešl, Martin - Leinveber, Pavel - Crha, Michal - Ladewig, Dorothy - Powers, Joanne - Suddendorf, Scott - Hodge, David O - Satam, Gaurav - Novák, Miroslav - Kára, Tomáš - Bruce, Charles J - Friedman, Paul A - Asirvatham, Samuel J
PY  - 2017
TI  - A Novel Defibrillation Tool Percutaneously Delivered, Partially Insulated Epicardial Defibrillation
JF  - JACC: Clinical Electrophysiology
VL  - 3
IS  - 7
SP  - 747-755
EP  - 747-755
PB  - Elsevier
SN  - 2405500X
KW  - arrhythmiadefibrillationepicardialinsulationICDpercutaneous
UR  - http://www.sciencedirect.com/science/article/pii/S2405500X17300919
L2  - http://www.sciencedirect.com/science/article/pii/S2405500X17300919
N2  - OBJECTIVES We aimed to develop a percutaneous defibrillation system with partially insulated epicardial coils to focus electrical energy on the myocardium and prevent or minimize extracardiac stimulation. BACKGROUND Epicardial defibrillation systems currently require surgical access. METHODS We tested 2 prototypes created for percutaneous introduction into the pericardial space via a steerable sheath. This testing included a partially insulated defibrillation coil and a defibrillation mesh with a urethane balloon acting as an insulator to the face of the mesh not in contact with the epicardium. The average energy associated with a chance of successful defibrillation 75% of the time was calculated for each experiment. RESULTS Of 16 animal experiments, 3 pig experiments had malfunctioning mesh prototypes such that results were unreliable; these were excluded. Therefore, 13 animal experiments were analyzed, 6 in canines (29.8 4.0 kg) and 7 in pigs (41.1 4.4 kg). The overall chance of successful defibrillation 75% of the time was 12.8 6.7 J (10.9 9.1 J for canines and 14.4 3.9 J in pigs; p 0.37). The lowest chance of successful defibrillation 75% of the time obtained in canines was 2.5 J, whereas in pigs it was 9.5 J. The lowest energy resulting in successful defibrillation was 2 J in canines and 5 J in pigs. There was no evidence of coronary vessel injury or trauma to extrapericardial structures. CONCLUSIONS Percutaneous, epicardial defibrillation using a partially insulated coil is feasible and seems to be associated with low defibrillation thresholds. Focusing insulation may limit extracardiac stimulation and potentially lower energy requirements for efficient defibrillation
ER  -

KILLU, Ammar M; Niyada NAKSUK; Zdeněk STÁREK; Christopher V DESIMONE; Faisal F SYED; Prakriti GABA; Jiří WOLF; František LEHAR; Martin PEŠL; Pavel LEINVEBER; Michal CRHA; Dorothy LADEWIG; Joanne POWERS; Scott SUDDENDORF; David O HODGE; Gaurav SATAM; Miroslav NOVÁK; Tomáš KÁRA; Charles J BRUCE; Paul A FRIEDMAN a Samuel J ASIRVATHAM. A Novel Defibrillation Tool Percutaneously Delivered, Partially Insulated Epicardial Defibrillation. \textit{JACC: Clinical Electrophysiology}. New York: Elsevier, 2017, roč.~3, č.~7, s.~747-755. ISSN~2405-500X. Dostupné z: https://doi.org/10.1016/j.jacep.2016.12.025.

Přehled o publikaci