KOBLIZEK, Vladimir, Branislava MILENKOVIC, Adam BARCZYK, Ruzena TKACOVA, Attila SOMFAY, Kirill ZYKOV, Neven TUDORIC, Kosta KOSTOV, Zuzana ZBOŽÍNKOVÁ, Jan ŠVANCARA, Jurij SORLI, Alvils KRAMS, Marc MIRAVITLLES a Arschang VALIPOUR. Phenotypes of COPD patients with a smoking history in Central and Eastern Europe: the POPE Study. European Respiratory Journal. Sheffield: European Respiratory Society Journals Ltd., roč. 49, č. 5, s. 1-10. ISSN 0903-1936. doi:10.1183/13993003.01446-2016. 2017.
Další formáty:   BibTeX LaTeX RIS
Základní údaje
Originální název Phenotypes of COPD patients with a smoking history in Central and Eastern Europe: the POPE Study
Autoři KOBLIZEK, Vladimir (203 Česká republika), Branislava MILENKOVIC (688 Srbsko), Adam BARCZYK (616 Polsko), Ruzena TKACOVA (703 Slovensko), Attila SOMFAY (348 Maďarsko), Kirill ZYKOV (643 Rusko), Neven TUDORIC (191 Chorvatsko), Kosta KOSTOV (100 Bulharsko), Zuzana ZBOŽÍNKOVÁ (203 Česká republika, garant, domácí), Jan ŠVANCARA (203 Česká republika, domácí), Jurij SORLI (705 Slovinsko), Alvils KRAMS (440 Litva), Marc MIRAVITLLES (724 Španělsko) a Arschang VALIPOUR (40 Rakousko).
Vydání European Respiratory Journal, Sheffield, European Respiratory Society Journals Ltd. 2017, 0903-1936.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30203 Respiratory systems
Stát vydavatele Velká Británie a Severní Irsko
Utajení není předmětem státního či obchodního tajemství
Impakt faktor Impact factor: 12.244
Kód RIV RIV/00216224:14110/17:00096971
Organizační jednotka Lékařská fakulta
Doi http://dx.doi.org/10.1183/13993003.01446-2016
UT WoS 000401788800005
Klíčová slova anglicky Chronic obstructive pulmonary disease
Štítky EL OK
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: Soňa Böhmová, učo 232884. Změněno: 20. 3. 2018 17:32.
Anotace
Chronic obstructive pulmonary disease (COPD) represents a major health problem in Central and Eastern European (CEE) countries; however, there are no data regarding clinical phenotypes of these patients in this region. Participation in the Phenotypes of COPD in Central and Eastern Europe (POPE) study was offered to stable patients with COPD in a real-life setting. The primary aim of this study was to assess the prevalence of phenotypes according to predefined criteria. Secondary aims included analysis of differences in symptom load, comorbidities and pharmacological treatment. 3362 patients with COPD were recruited in 10 CEE countries. 63% of the population were nonexacerbators, 20.4% frequent exacerbators with chronic bronchitis, 9.5% frequent exacerbators without chronic bronchitis and 6.9% were classified as asthma-COPD overlap. Differences in the distribution of phenotypes between countries were observed, with the highest heterogeneity observed in the nonexacerbator cohort and the lowest heterogeneity observed in the asthma-COPD cohort. There were statistically significant differences in symptom load, lung function, comorbidities and treatment between these phenotypes. The majority of patients with stable COPD in CEE are nonexacerbators; however, there are distinct differences in surrogates of disease severity and therapy between predefined COPD phenotypes.
VytisknoutZobrazeno: 28. 3. 2024 11:29