Orosensory detection of bitter in fat-taster healthy and obese
participants: Genetic polymorphism of CD36 and TAS2R38

J 2018

Orosensory detection of bitter in fat-taster healthy and obese participants: Genetic polymorphism of CD36 and TAS2R38

KARMOUS, Inchirah; Jiří PLESNÍK; Amira SAYED KHAN; Omar ŠERÝ; Abdelmajid ABID et al.

Základní údaje

Originální název

Orosensory detection of bitter in fat-taster healthy and obese participants: Genetic polymorphism of CD36 and TAS2R38

Autoři

KARMOUS, Inchirah; Jiří PLESNÍK; Amira SAYED KHAN; Omar ŠERÝ; Abdelmajid ABID; Amani MANKAI; Abdellah AOUIDET a Naim Akhtar KHAN

Vydání

Clinical Nutrition, P. Ribou, 2018, 0261-5614

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30105 Physiology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 6.402

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/18:00102008

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova česky

tuk z potravin; buňky chuťových pohárků; percepce

Klíčová slova anglicky

DIETARY-FAT; BUD CELLS; PERCEPTION

Změněno: 23. 4. 2024 09:35, Mgr. Michal Petr

Anotace

V originále

We assessed orosensory detection of a long-chain fatty acid, linoleic acid (LA), and a bitter taste marker, 6-n-propylthiouracil (PROP), and correlated lipid-taster subjects with PROP detection and polymorphism in genes encoding bitter and lipid taste receptors, respectively, TAS2R38 and CD36, in normal weight and obese subjects. The study included the participants who could detect LA, i.e., lipid-tasters. There was a positive correlation between BMI and detection thresholds for fat and bitter taste in normal weight and obese subjects. Obese participants showed a positive correlation between LA and PROP detection thresholds. PROP detection thresholds were higher for CD36 SNP (rs1761667) and TAS2R38 SNPs (rs1726866 and rs10246939) in obese participants compared to normal weight subjects. LA detection thresholds were not high for CD36 SNP (rs1761667) or TAS2R38 SNP (rs1726866 and rs10246939) in obese participants. Orosensory detection thresholds for fat and bitter taste are associated with BMI, and CD36 and TAS2R38 genotypes are not always associated with taste phenotypes.

Citovat

KARMOUS, Inchirah; Jiří PLESNÍK; Amira SAYED KHAN; Omar ŠERÝ; Abdelmajid ABID; Amani MANKAI; Abdellah AOUIDET a Naim Akhtar KHAN. Orosensory detection of bitter in fat-taster healthy and obese participants: Genetic polymorphism of CD36 and TAS2R38. Clinical Nutrition. P. Ribou, 2018, roč. 37, č. 1, s. 313-320. ISSN 0261-5614. Dostupné z: https://doi.org/10.1016/j.clnu.2017.06.004.

@article{1385603,
   author = {Karmous, Inchirah and Plesník, Jiří and Sayed Khan, Amira and Šerý, Omar and Abid, Abdelmajid and Mankai, Amani and Aouidet, Abdellah and Khan, Naim Akhtar},
   article_number = {1},
   doi = {https://doi.org/10.1016/j.clnu.2017.06.004},
   keywords = {DIETARY-FAT; BUD CELLS; PERCEPTION},
   language = {eng},
   issn = {0261-5614},
   journal = {Clinical Nutrition},
   title = {Orosensory detection of bitter in fat-taster healthy and obese participants: Genetic polymorphism of CD36 and TAS2R38},
   url = {http://dx.doi.org/10.1016/j.clnu.2017.06.004},
   volume = {37},
   year = {2018}
}

TY  - JOUR
ID  - 1385603
AU  - Karmous, Inchirah - Plesník, Jiří - Sayed Khan, Amira - Šerý, Omar - Abid, Abdelmajid - Mankai, Amani - Aouidet, Abdellah - Khan, Naim Akhtar
PY  - 2018
TI  - Orosensory detection of bitter in fat-taster healthy and obese participants: Genetic polymorphism of CD36 and TAS2R38
JF  - Clinical Nutrition
VL  - 37
IS  - 1
SP  - 313-320
EP  - 313-320
PB  - P. Ribou
SN  - 02615614
KW  - DIETARY-FAT
KW  - BUD CELLS
KW  - PERCEPTION
UR  - http://dx.doi.org/10.1016/j.clnu.2017.06.004
N2  - We assessed orosensory detection of a long-chain fatty acid, linoleic acid (LA), and a bitter taste marker, 6-n-propylthiouracil (PROP), and correlated lipid-taster subjects with PROP detection and polymorphism in genes encoding bitter and lipid taste receptors, respectively, TAS2R38 and CD36, in normal weight and obese subjects. The study included the participants who could detect LA, i.e., lipid-tasters. There was a positive correlation between BMI and detection thresholds for fat and bitter taste in normal weight and obese subjects. Obese participants showed a positive correlation between LA and PROP detection thresholds. PROP detection thresholds were higher for CD36 SNP (rs1761667) and TAS2R38 SNPs (rs1726866 and rs10246939) in obese participants compared to normal weight subjects. LA detection thresholds were not high for CD36 SNP (rs1761667) or TAS2R38 SNP (rs1726866 and rs10246939) in obese participants. Orosensory detection thresholds for fat and bitter taste are associated with BMI, and CD36 and TAS2R38 genotypes are not always associated with taste phenotypes.
ER  -

KARMOUS, Inchirah; Jiří PLESNÍK; Amira SAYED KHAN; Omar ŠERÝ; Abdelmajid ABID; Amani MANKAI; Abdellah AOUIDET a Naim Akhtar KHAN. Orosensory detection of bitter in fat-taster healthy and obese participants: Genetic polymorphism of CD36 and TAS2R38. \textit{Clinical Nutrition}. P. Ribou, 2018, roč.~37, č.~1, s.~313-320. ISSN~0261-5614. Dostupné z: https://doi.org/10.1016/j.clnu.2017.06.004.

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