Minimally invasive mitral valve repair for functional mitral
regurgitation in severe heart failure: MitraClip versus
minimally invasive surgical approach

J 2016

Minimally invasive mitral valve repair for functional mitral regurgitation in severe heart failure: MitraClip versus minimally invasive surgical approach

ONDRÚŠ, Tomáš; Jozef BARTUNEK; Marc VANDERHEYDEN; B STOCKMAN; Martin KOTRC et al.

Základní údaje

Originální název

Minimally invasive mitral valve repair for functional mitral regurgitation in severe heart failure: MitraClip versus minimally invasive surgical approach

Autoři

ONDRÚŠ, Tomáš; Jozef BARTUNEK; Marc VANDERHEYDEN; B STOCKMAN; Martin KOTRC; Frank VAN PRAET; Guy VAN CAMP; Patrick LECOMTE; Yujing MO a Martin PENICKA

Vydání

Interactive CardioVascular and Thoracic Surgery, OXFORD, OXFORD UNIV PRESS, 2016, 1569-9293

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.857

Označené pro přenos do RIV

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1093/icvts/ivw215

UT WoS

000388000500020

Klíčová slova anglicky

MitraClip; Mitral valve repair; Functional mitral regurgitation; Outcome

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 31. 8. 2017 12:29, Soňa Böhmová

Anotace

V originále

To compare the outcomes of MitraClip versus minimally invasive surgical mitral valve repair in high-risk patients with significant functional mitral regurgitation (FMR) and severe heart failure in a centre having pilot versus extensive experience with the MitraClip and the minimally invasive surgical approach, respectively. The MitraClip group consisted of 24 high-surgical-risk patients [age 75 +/- 9 years, 75% males, NYHA III/IV 88%, left ventricular (LV) ejection fraction 31 +/- 9%, EuroSCORE II 18 +/- 14%], while the surgical group consisted of 48 patients matched for age, NYHA class and LV ejection fraction. Patients undergoing MitraClip versus those undergoing surgical repair showed higher prevalence of ischaemic LV dysfunction and larger LV end-diastolic diameter (both P < 0.05). Both the MitraClip and the surgical repair groups had similar 30-day mortality rates (4 vs 13%, P = 0.41) and prevalence of serious adverse events (25 vs 38%, P = 0.43). The median follow-up was 1028 days (IQR: 272-1564 days) in the MitraClip group and 890 days (IQR: 436-1381 days) in the surgical group (P = 0.95). Total all-cause mortality (54 vs 60%, log-rank P = 0.64) and rates of rehospitalizations for heart failure (42 vs 29%, log-rank P = 0.68) did not differ significantly between groups. Both techniques were associated with significant decrease in NYHA class and severity of FMR (P < 0.001 for all) and with a similar degree of stabilization of LV remodelling (P = NS). Despite the significant baseline differences in accumulated expertise and risk profile between the surgical and the MitraClip groups, both minimally invasive techniques were associated with similar 30-day and long-term outcomes.

Citovat

ONDRÚŠ, Tomáš; Jozef BARTUNEK; Marc VANDERHEYDEN; B STOCKMAN; Martin KOTRC; Frank VAN PRAET; Guy VAN CAMP; Patrick LECOMTE; Yujing MO a Martin PENICKA. Minimally invasive mitral valve repair for functional mitral regurgitation in severe heart failure: MitraClip versus minimally invasive surgical approach. Interactive CardioVascular and Thoracic Surgery. OXFORD: OXFORD UNIV PRESS, 2016, roč. 23, č. 5, s. 784-789. ISSN 1569-9293. Dostupné z: https://doi.org/10.1093/icvts/ivw215.

@article{1388241,
   author = {Ondrúš, Tomáš and Bartunek, Jozef and Vanderheyden, Marc and Stockman, B and Kotrc, Martin and Van Praet, Frank and Van Camp, Guy and Lecomte, Patrick and Mo, Yujing and Penicka, Martin},
   article_location = {OXFORD},
   article_number = {5},
   doi = {https://doi.org/10.1093/icvts/ivw215},
   keywords = {MitraClip; Mitral valve repair; Functional mitral regurgitation; Outcome},
   language = {eng},
   issn = {1569-9293},
   journal = {Interactive CardioVascular and Thoracic Surgery},
   title = {Minimally invasive mitral valve repair for functional mitral regurgitation in severe heart failure: MitraClip versus minimally invasive surgical approach},
   url = {http://dx.doi.org/10.1093/icvts/ivw215},
   volume = {23},
   year = {2016}
}

TY  - JOUR
ID  - 1388241
AU  - Ondrúš, Tomáš - Bartunek, Jozef - Vanderheyden, Marc - Stockman, B - Kotrc, Martin - Van Praet, Frank - Van Camp, Guy - Lecomte, Patrick - Mo, Yujing - Penicka, Martin
PY  - 2016
TI  - Minimally invasive mitral valve repair for functional mitral regurgitation in severe heart failure: MitraClip versus minimally invasive surgical approach
JF  - Interactive CardioVascular and Thoracic Surgery
VL  - 23
IS  - 5
SP  - 784-789
EP  - 784-789
PB  - OXFORD UNIV PRESS
SN  - 15699293
KW  - MitraClip
KW  - Mitral valve repair
KW  - Functional mitral regurgitation
KW  - Outcome
UR  - http://dx.doi.org/10.1093/icvts/ivw215
L2  - http://dx.doi.org/10.1093/icvts/ivw215
N2  - To compare the outcomes of MitraClip versus minimally invasive surgical mitral valve repair in high-risk patients with significant functional mitral regurgitation (FMR) and severe heart failure in a centre having pilot versus extensive experience with the MitraClip and the minimally invasive surgical approach, respectively. The MitraClip group consisted of 24 high-surgical-risk patients [age 75 +/- 9 years, 75% males, NYHA III/IV 88%, left ventricular (LV) ejection fraction 31 +/- 9%, EuroSCORE II 18 +/- 14%], while the surgical group consisted of 48 patients matched for age, NYHA class and LV ejection fraction. Patients undergoing MitraClip versus those undergoing surgical repair showed higher prevalence of ischaemic LV dysfunction and larger LV end-diastolic diameter (both P < 0.05). Both the MitraClip and the surgical repair groups had similar 30-day mortality rates (4 vs 13%, P = 0.41) and prevalence of serious adverse events (25 vs 38%, P = 0.43). The median follow-up was 1028 days (IQR: 272-1564 days) in the MitraClip group and 890 days (IQR: 436-1381 days) in the surgical group (P = 0.95). Total all-cause mortality (54 vs 60%, log-rank P = 0.64) and rates of rehospitalizations for heart failure (42 vs 29%, log-rank P = 0.68) did not differ significantly between groups. Both techniques were associated with significant decrease in NYHA class and severity of FMR (P < 0.001 for all) and with a similar degree of stabilization of LV remodelling (P = NS). Despite the significant baseline differences in accumulated expertise and risk profile between the surgical and the MitraClip groups, both minimally invasive techniques were associated with similar 30-day and long-term outcomes.
ER  -

ONDRÚŠ, Tomáš; Jozef BARTUNEK; Marc VANDERHEYDEN; B STOCKMAN; Martin KOTRC; Frank VAN PRAET; Guy VAN CAMP; Patrick LECOMTE; Yujing MO a Martin PENICKA. Minimally invasive mitral valve repair for functional mitral regurgitation in severe heart failure: MitraClip versus minimally invasive surgical approach. \textit{Interactive CardioVascular and Thoracic Surgery}. OXFORD: OXFORD UNIV PRESS, 2016, roč.~23, č.~5, s.~784-789. ISSN~1569-9293. Dostupné z: https://doi.org/10.1093/icvts/ivw215.

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