H-1-antihistamines and oxidative burst of professional
phagocytes

J 2009

H-1-antihistamines and oxidative burst of professional phagocytes

NOSÁL, Radomír; Katarína DRÁBIKOVÁ; Viera JANČINOVÁ; J MORAVCOVA; Antonín LOJEK et al.

Základní údaje

Originální název

H-1-antihistamines and oxidative burst of professional phagocytes

Autoři

NOSÁL, Radomír; Katarína DRÁBIKOVÁ; Viera JANČINOVÁ; J MORAVCOVA; Antonín LOJEK; Milan ČÍŽ; T MACICKOVA a Jana PEČIVOVÁ

Vydání

Neuroendocrinology Letters, STOCKHOLM, MAGHIRA & MAAS PUBLICATIONS, 2009, 0172-780X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.047

Označené pro přenos do RIV

UT WoS

000275266600026

Klíčová slova anglicky

H-1-antihistamines; neutrophils; chemiluminescence; EC50 values

Změněno: 12. 9. 2017 12:45, doc. RNDr. Milan Číž, Ph.D.

Anotace

V originále

OBJECTIVES: We analysed and compared the effect of five H-1-antihistamines on stimulated oxidative burst at extra- and intracellular level of isolated and stimulated human polymorphonuclear leukocytes. DESIGN: Oxidative burst of isolated human neutrophils was studied by means of luminol and isoluminol enhanced chemiluminescence. RESULTS: The following rank order of potency for H-1-antihistamines to decrease chemiluminescence was evaluated extracellularly: dithiaden> loratadine> chlorpheniramine> brompheniramine> pheniramine and at intracellular site: loratadine> dithiaden. CONCLUSION: H-1-antihistamines differ substantially according to their chemical structure in suppressing oxidative burst both at extra- and intracellular site of isolated stimulated human neutrophils.

Citovat

NOSÁL, Radomír; Katarína DRÁBIKOVÁ; Viera JANČINOVÁ; J MORAVCOVA; Antonín LOJEK; Milan ČÍŽ; T MACICKOVA a Jana PEČIVOVÁ. H-1-antihistamines and oxidative burst of professional phagocytes. Neuroendocrinology Letters. STOCKHOLM: MAGHIRA & MAAS PUBLICATIONS, 2009, roč. 30, s. 133-136. ISSN 0172-780X.

@article{1389173,
   author = {Nosál, Radomír and Drábiková, Katarína and Jančinová, Viera and Moravcova, J and Lojek, Antonín and Číž, Milan and Macickova, T and Pečivová, Jana},
   article_location = {STOCKHOLM},
   keywords = {H-1-antihistamines; neutrophils; chemiluminescence; EC50 values},
   language = {eng},
   issn = {0172-780X},
   journal = {Neuroendocrinology Letters},
   title = {H-1-antihistamines and oxidative burst of professional phagocytes},
   volume = {30},
   year = {2009}
}

TY  - JOUR
ID  - 1389173
AU  - Nosál, Radomír - Drábiková, Katarína - Jančinová, Viera - Moravcova, J - Lojek, Antonín - Číž, Milan - Macickova, T - Pečivová, Jana
PY  - 2009
TI  - H-1-antihistamines and oxidative burst of professional phagocytes
JF  - Neuroendocrinology Letters
VL  - 30
SP  - 133-136
EP  - 133-136
PB  - MAGHIRA & MAAS PUBLICATIONS
SN  - 0172780X
KW  - H-1-antihistamines
KW  - neutrophils
KW  - chemiluminescence
KW  - EC50 values
N2  - OBJECTIVES: We analysed and compared the effect of five H-1-antihistamines on stimulated oxidative burst at extra- and intracellular level of isolated and stimulated human polymorphonuclear leukocytes. DESIGN: Oxidative burst of isolated human neutrophils was studied by means of luminol and isoluminol enhanced chemiluminescence. RESULTS: The following rank order of potency for H-1-antihistamines to decrease chemiluminescence was evaluated extracellularly: dithiaden> loratadine> chlorpheniramine> brompheniramine> pheniramine and at intracellular site: loratadine> dithiaden. CONCLUSION: H-1-antihistamines differ substantially according to their chemical structure in suppressing oxidative burst both at extra- and intracellular site of isolated stimulated human neutrophils.
ER  -

NOSÁL, Radomír; Katarína DRÁBIKOVÁ; Viera JANČINOVÁ; J MORAVCOVA; Antonín LOJEK; Milan ČÍŽ; T MACICKOVA a Jana PEČIVOVÁ. H-1-antihistamines and oxidative burst of professional phagocytes. \textit{Neuroendocrinology Letters}. STOCKHOLM: MAGHIRA \&{}amp; MAAS PUBLICATIONS, 2009, roč.~30, s.~133-136. ISSN~0172-780X.

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