Modulation of neutrophil oxidative burst via histamine receptors

ČÍŽ, Milan a Antonín LOJEK. Modulation of neutrophil oxidative burst via histamine receptors. British Journal of Pharmacology. HOBOKEN: Wiley-Blackwell, 2013, roč. 170, č. 1, s. 17-22. ISSN 0007-1188. Dostupné z: https://doi.org/10.1111/bph.12107.

Základní údaje

Originální název

Modulation of neutrophil oxidative burst via histamine receptors

Autoři

ČÍŽ, Milan a Antonín LOJEK

Vydání

British Journal of Pharmacology, HOBOKEN, Wiley-Blackwell, 2013, 0007-1188

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Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 4.990

Označené pro přenos do RIV

Ne

DOI

https://doi.org/10.1111/bph.12107

UT WoS

000323131600003

Klíčová slova anglicky

neutrophil; oxidative burst; reactive oxygen species; histamine; histamine receptor

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Anotace

V originále

Histamine has the ability to influence the activity of immune cells including neutrophils and plays a pivotal role in inflammatory processes, which are a complex network of cellular and humoral events. One of the main functions manifested by activated neutrophils is oxidative burst, which is linked to the production of reactive oxygen species; therefore, the effects of histamine receptor agonists and antagonists on the oxidative burst of neutrophils is reviewed. A role for the well-characterized histamine H-1 and H-2 receptors in this process is discussed and compared to that of the recently discovered H-4 receptor.