Metal-organic frameworks as sorbents for pre-concentration of
drugs and small peptides in MALDI TOF MS

k 2017

Metal-organic frameworks as sorbents for pre-concentration of drugs and small peptides in MALDI TOF MS

KOLÁŘOVÁ, Lenka, Lukáš PEČINKA, Eladia Maria PEŇA MENDÉZ, Jose Elias CONDE, Josef HAVEL et. al.

Základní údaje

Originální název

Metal-organic frameworks as sorbents for pre-concentration of drugs and small peptides in MALDI TOF MS

Autoři

KOLÁŘOVÁ, Lenka (203 Česká republika, domácí), Lukáš PEČINKA (203 Česká republika, domácí), Eladia Maria PEŇA MENDÉZ (724 Španělsko), Jose Elias CONDE (724 Španělsko) a Josef HAVEL (203 Česká republika, garant, domácí)

Vydání

Green materials (Ionic Liquids, Metal Organic Frameworks and Nanomaterials) for the Selective Environmental Monitoring of Pollutants from Water, ULL, Tenerife, 19th June 2017,oral presentation, 2017

Další údaje

Jazyk

angličtina

Typ výsledku

Prezentace na konferencích

Obor

10406 Analytical chemistry

Stát vydavatele

Španělsko

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14310/17:00098935

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

metal organic frameworks; mass spectrometry; SALDI; MALDI; drugs

Změněno: 9. 10. 2020 14:09, Mgr. Lukáš Pečinka, Ph.D.

Anotace

V originále

Metal organic frameworks are highly porous and due to high surface area very promising materials for application as a sorbent. In this work various type of Metal organic frameworks (MOFs) as a tool for specific preconcentration of peptides and for small molecules as drugs were investigated. We found specific interaction of two peptides (angiotensin II and adrenocorticotropic hormone clip [1-17]) and we was able to pre-concentrated them 2 x and 120x using Basolite F300 and using Matrix-assisted laser desorption/ionization connecting with time of flight detection (TOF) mass spectroscopy (MS).

Citovat

KOLÁŘOVÁ, Lenka, Lukáš PEČINKA, Eladia Maria PEŇA MENDÉZ, Jose Elias CONDE a Josef HAVEL. Metal-organic frameworks as sorbents for pre-concentration of drugs and small peptides in MALDI TOF MS. In Green materials (Ionic Liquids, Metal Organic Frameworks and Nanomaterials) for the Selective Environmental Monitoring of Pollutants from Water, ULL, Tenerife, 19th June 2017,oral presentation. 2017.

@proceedings{1400309,
   author = {Kolářová, Lenka and Pečinka, Lukáš and Peňa Mendéz, Eladia Maria and Conde, Jose Elias and Havel, Josef},
   booktitle = {Green materials (Ionic Liquids, Metal Organic Frameworks and Nanomaterials) for the Selective Environmental Monitoring of Pollutants from Water, ULL, Tenerife, 19th June 2017,oral presentation},
   keywords = {metal organic frameworks; mass spectrometry; SALDI; MALDI; drugs},
   language = {eng},
   title = {Metal-organic frameworks as sorbents for pre-concentration of drugs and small peptides in MALDI TOF MS},
   year = {2017}
}

TY  - CONF
ID  - 1400309
AU  - Kolářová, Lenka - Pečinka, Lukáš - Peňa Mendéz, Eladia Maria - Conde, Jose Elias - Havel, Josef
PY  - 2017
TI  - Metal-organic frameworks as sorbents for pre-concentration of drugs and small peptides in MALDI TOF MS
KW  - metal organic frameworks
KW  - mass spectrometry
KW  - SALDI
KW  - MALDI
KW  - drugs
N2  - Metal organic frameworks are highly porous and due to high surface area very promising materials for application as a sorbent. In this work various type of Metal organic frameworks (MOFs) as a tool for specific preconcentration of peptides and for small molecules as drugs were investigated. We found specific interaction of two peptides (angiotensin II and adrenocorticotropic hormone clip [1-17]) and we was able to pre-concentrated them 2 x and 120x using Basolite F300 and using Matrix-assisted laser desorption/ionization connecting with time of flight detection (TOF) mass spectroscopy (MS).
ER  -

KOLÁŘOVÁ, Lenka, Lukáš PEČINKA, Eladia Maria PEŇA MENDÉZ, Jose Elias CONDE a Josef HAVEL. Metal-organic frameworks as sorbents for pre-concentration of drugs and small peptides in MALDI TOF MS. In \textit{Green materials (Ionic Liquids, Metal Organic Frameworks and Nanomaterials) for the Selective Environmental Monitoring of Pollutants from Water, ULL, Tenerife, 19th June 2017,oral presentation}. 2017.

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