Atypical handedness in mesial temporal lobe epilepsy

J 2017

Atypical handedness in mesial temporal lobe epilepsy

DOLEŽALOVÁ, Irena; S. SCHACHTER; Jan CHRASTINA; Jan HEMZA; Markéta HERMANOVÁ et. al.

Základní údaje

Originální název

Atypical handedness in mesial temporal lobe epilepsy

Autoři

DOLEŽALOVÁ, Irena (203 Česká republika, garant, domácí); S. SCHACHTER (840 Spojené státy); Jan CHRASTINA (203 Česká republika, domácí); Jan HEMZA (203 Česká republika, domácí); Markéta HERMANOVÁ (203 Česká republika, domácí); Ivan REKTOR (203 Česká republika, domácí); Marta PAŽOURKOVÁ (203 Česká republika, domácí) a Milan BRÁZDIL (203 Česká republika, domácí)

Vydání

EPILEPSY & BEHAVIOR, SAN DIEGO, ACADEMIC PRESS INC ELSEVIER SCIENCE, 2017, 1525-5050

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30103 Neurosciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.600

Kód RIV

RIV/00216224:14110/17:00099039

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1016/j.yebeh.2017.01.034

UT WoS

000406321300014

EID Scopus

2-s2.0-85019685646

Klíčová slova anglicky

Mesial temporal lobe epilepsy; Handedness; Left-handed; Right-handed; Age at epilepsy onset; Atypical dominance

Štítky

EL OK, podil

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 12. 3. 2018 15:29, Soňa Böhmová

Anotace

V originále

Objective: The main aim of our study was to investigate the handedness of patients with mesial temporal lobe epilepsy (MTLE). We also sought to identify clinical variables that correlated with left-handedness in this population. Methods: Handedness (laterality quotient) was assessed in 73 consecutive patients with MTLE associated with unilateral hippocampal sclerosis (HS) using the Edinburgh Handedness Inventory. Associations between rightand left-handedness and clinical variables were investigated. Results: We found that 54 (74.0%) patients were right-handed, and 19 (26%) patients were left-handed. There were 15 (36.6%) left-handed patients with left-sided seizure onset compared to 4 (12.5%) left-handed patients with right-sided seizure onset (p = 0.030). Among patients with left-sided MTLE, age at epilepsy onset was significantly correlated with handedness (8 years of age [median; min-max 0.5-17] in left-handers versus 15 years of age [median; min-max 3-30] in right-handers (p < 0.001). Conclusions: Left-sided MTLE is associatedwith atypical handedness, especiallywhen seizure onset occurs during an active period of brain development, suggesting a bi-hemispheric neuroplastic process for establishing motor dominance in patients with early-onset left-sided MTLE. (C) 2017 Elsevier Inc. All rights reserved.

Citovat

DOLEŽALOVÁ, Irena; S. SCHACHTER; Jan CHRASTINA; Jan HEMZA; Markéta HERMANOVÁ; Ivan REKTOR; Marta PAŽOURKOVÁ a Milan BRÁZDIL. Atypical handedness in mesial temporal lobe epilepsy. EPILEPSY & BEHAVIOR. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2017, roč. 72, JUL 2017, s. 78-81. ISSN 1525-5050. Dostupné z: https://doi.org/10.1016/j.yebeh.2017.01.034.

@article{1400988,
   author = {Doležalová, Irena and Schachter, S. and Chrastina, Jan and Hemza, Jan and Hermanová, Markéta and Rektor, Ivan and Pažourková, Marta and Brázdil, Milan},
   article_location = {SAN DIEGO},
   article_number = {JUL 2017},
   doi = {https://doi.org/10.1016/j.yebeh.2017.01.034},
   keywords = {Mesial temporal lobe epilepsy; Handedness; Left-handed; Right-handed; Age at epilepsy onset; Atypical dominance},
   language = {eng},
   issn = {1525-5050},
   journal = {EPILEPSY & BEHAVIOR},
   title = {Atypical handedness in mesial temporal lobe epilepsy},
   volume = {72},
   year = {2017}
}

TY  - JOUR
ID  - 1400988
AU  - Doležalová, Irena - Schachter, S. - Chrastina, Jan - Hemza, Jan - Hermanová, Markéta - Rektor, Ivan - Pažourková, Marta - Brázdil, Milan
PY  - 2017
TI  - Atypical handedness in mesial temporal lobe epilepsy
JF  - EPILEPSY & BEHAVIOR
VL  - 72
IS  - JUL 2017
SP  - 78-81
EP  - 78-81
PB  - ACADEMIC PRESS INC ELSEVIER SCIENCE
SN  - 15255050
KW  - Mesial temporal lobe epilepsy
KW  - Handedness
KW  - Left-handed
KW  - Right-handed
KW  - Age at epilepsy onset
KW  - Atypical dominance
N2  - Objective: The main aim of our study was to investigate the handedness of patients with mesial temporal lobe epilepsy (MTLE). We also sought to identify clinical variables that correlated with left-handedness in this population. Methods: Handedness (laterality quotient) was assessed in 73 consecutive patients with MTLE associated with unilateral hippocampal sclerosis (HS) using the Edinburgh Handedness Inventory. Associations between rightand left-handedness and clinical variables were investigated. Results: We found that 54 (74.0%) patients were right-handed, and 19 (26%) patients were left-handed. There were 15 (36.6%) left-handed patients with left-sided seizure onset compared to 4 (12.5%) left-handed patients with right-sided seizure onset (p = 0.030). Among patients with left-sided MTLE, age at epilepsy onset was significantly correlated with handedness (8 years of age [median; min-max 0.5-17] in left-handers versus 15 years of age [median; min-max 3-30] in right-handers (p < 0.001). Conclusions: Left-sided MTLE is associatedwith atypical handedness, especiallywhen seizure onset occurs during an active period of brain development, suggesting a bi-hemispheric neuroplastic process for establishing motor dominance in patients with early-onset left-sided MTLE. (C) 2017 Elsevier Inc. All rights reserved.
ER  -

DOLEŽALOVÁ, Irena; S. SCHACHTER; Jan CHRASTINA; Jan HEMZA; Markéta HERMANOVÁ; Ivan REKTOR; Marta PAŽOURKOVÁ a Milan BRÁZDIL. Atypical handedness in mesial temporal lobe epilepsy. \textit{EPILEPSY \&{}amp; BEHAVIOR}. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2017, roč.~72, JUL 2017, s.~78-81. ISSN~1525-5050. Dostupné z: https://doi.org/10.1016/j.yebeh.2017.01.034.

Přehled o publikaci