Diffusion tensor imaging (DTI) in patients with cystic fibrosis

BEDNAŘÍK, Petr; Alena SVÁTKOVÁ; Silvia MANGIA; Christophe LENGLET; Antoinette MORAN a Amir MOHEET. Diffusion tensor imaging (DTI) in patients with cystic fibrosis. In Joint annual meeting ISMRM-ESMRMB 2018. 2018.

Základní údaje

Originální název

Diffusion tensor imaging (DTI) in patients with cystic fibrosis

Název anglicky

Diffusion tensor imaging (DTI) in patients with cystic fibrosis

Autoři

BEDNAŘÍK, Petr; Alena SVÁTKOVÁ; Silvia MANGIA; Christophe LENGLET; Antoinette MORAN a Amir MOHEET

Vydání

Joint annual meeting ISMRM-ESMRMB 2018, 2018

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Další údaje

Typ výsledku

Konferenční abstrakt

Utajení

není předmětem státního či obchodního tajemství

Označené pro přenos do RIV

Ne

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Anotace

V originále

Cystic fibrosis (CF) is the most common fatal autosomal recessive disorder in Caucasians. As the effects of CF on the brain structure remain unexplored, we piloted initial MRI investigations of brain structure by diffusion tensor imaging in CF and cystic fibrosis related diabetes (CFRD), a common complication in CF patients. Diffusion metrics were obtained in selected white and gray matter regions of 5 healthy controls (HC) and 5 CF patients with CFRD. Diffusion metrics of deep gray matter structures appeared to differ between patients with CF and HC, possibly related to increased iron deposition, warranting more comprehensive MRI investigations in larger cohorts of patients.

Anglicky

Cystic fibrosis (CF) is the most common fatal autosomal recessive disorder in Caucasians. As the effects of CF on the brain structure remain unexplored, we piloted initial MRI investigations of brain structure by diffusion tensor imaging in CF and cystic fibrosis related diabetes (CFRD), a common complication in CF patients. Diffusion metrics were obtained in selected white and gray matter regions of 5 healthy controls (HC) and 5 CF patients with CFRD. Diffusion metrics of deep gray matter structures appeared to differ between patients with CF and HC, possibly related to increased iron deposition, warranting more comprehensive MRI investigations in larger cohorts of patients.