2017
Aerosol Health Effects from Molecular to Global Scales
SHIRAIWA, Manabu; Kayo UEDA; Andrea POZZER; Gerhard LAMMEL; Christopher J. KAMPF et al.Základní údaje
Originální název
Aerosol Health Effects from Molecular to Global Scales
Autoři
SHIRAIWA, Manabu; Kayo UEDA; Andrea POZZER; Gerhard LAMMEL; Christopher J. KAMPF; Akihiro FUSHIMI; Shinichi ENAMI; Andrea M. ARANGIO; Janine FROHLICH-NOWOISKY; Yuji FUJITANI; Akiko FURUYAMA; Pascale S. J. LAKEY; Jos LELIEVELD; Kurt LUCAS; Yu MORINO; Ulrich POSCHL; Satoshi TAKAHARNA; Akinori TAKAMI; Haijie TONG; Bettina WEBER; Ayako YOSHINO a Kei SATO
Vydání
ENVIRONMENTAL SCIENCE & TECHNOLOGY, WASHINGTON, AMER CHEMICAL SOC, 2017, 0013-936X
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
10511 Environmental sciences
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 6.653
Označené pro přenos do RIV
Ano
Kód RIV
RIV/00216224:14310/17:00100077
Organizační jednotka
Přírodovědecká fakulta
UT WoS
EID Scopus
Klíčová slova anglicky
SECONDARY ORGANIC AEROSOL; FINE-PARTICULATE MATTER; LONG-TERM EXPOSURE; POLYCYCLIC AROMATIC-HYDROCARBONS
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 28. 3. 2018 09:54, Ing. Nicole Zrilić
Anotace
V originále
Poor air quality is globally the largest environmental health risk. Epidemiological studies have uncovered clear relationships of gaseous pollutants and particulate matter (PM) with adverse health outcomes, including mortality by cardiovascular and respiratory diseases. Studies of health impacts by aerosols are highly multidisciplinary with a broad range of scales in space and time. We assess recent advances and future challenges regarding aerosol effects on health from molecular to global scales through epidemiological studies, field measurements, health-related properties of PM, and multiphase interactions of oxidants and PM upon respiratory deposition. Global modeling combined with epidemiological exposure response functions indicates that ambient air pollution causes more than four million premature deaths per year. Epidemiological studies usually refer to PM mass concentrations, but some health effects may relate to specific constituents such as bioaerosols, polycyclic aromatic compounds, and transition metals. Various analytical techniques and cellular and molecular assays are applied to assess the redox activity of PM and the formation of reactive oxygen species. Multiphase chemical interactions of lung antioxidants with atmospheric pollutants are crucial to the mechanistic and molecular understanding of oxidative stress upon respiratory deposition. The role of distinct PM components in health impacts and mortality needs to be clarified by integrated research on various spatiotemporal scales for better evaluation and mitigation of aerosol effects on public health in the Anthropocene.