J 2017

Aerosol Health Effects from Molecular to Global Scales

SHIRAIWA, Manabu; Kayo UEDA; Andrea POZZER; Gerhard LAMMEL; Christopher J. KAMPF et al.

Základní údaje

Originální název

Aerosol Health Effects from Molecular to Global Scales

Autoři

SHIRAIWA, Manabu; Kayo UEDA; Andrea POZZER; Gerhard LAMMEL; Christopher J. KAMPF; Akihiro FUSHIMI; Shinichi ENAMI; Andrea M. ARANGIO; Janine FROHLICH-NOWOISKY; Yuji FUJITANI; Akiko FURUYAMA; Pascale S. J. LAKEY; Jos LELIEVELD; Kurt LUCAS; Yu MORINO; Ulrich POSCHL; Satoshi TAKAHARNA; Akinori TAKAMI; Haijie TONG; Bettina WEBER; Ayako YOSHINO a Kei SATO

Vydání

ENVIRONMENTAL SCIENCE & TECHNOLOGY, WASHINGTON, AMER CHEMICAL SOC, 2017, 0013-936X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 6.653

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/17:00100077

Organizační jednotka

Přírodovědecká fakulta

EID Scopus

Klíčová slova anglicky

SECONDARY ORGANIC AEROSOL; FINE-PARTICULATE MATTER; LONG-TERM EXPOSURE; POLYCYCLIC AROMATIC-HYDROCARBONS

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 28. 3. 2018 09:54, Ing. Nicole Zrilić

Anotace

V originále

Poor air quality is globally the largest environmental health risk. Epidemiological studies have uncovered clear relationships of gaseous pollutants and particulate matter (PM) with adverse health outcomes, including mortality by cardiovascular and respiratory diseases. Studies of health impacts by aerosols are highly multidisciplinary with a broad range of scales in space and time. We assess recent advances and future challenges regarding aerosol effects on health from molecular to global scales through epidemiological studies, field measurements, health-related properties of PM, and multiphase interactions of oxidants and PM upon respiratory deposition. Global modeling combined with epidemiological exposure response functions indicates that ambient air pollution causes more than four million premature deaths per year. Epidemiological studies usually refer to PM mass concentrations, but some health effects may relate to specific constituents such as bioaerosols, polycyclic aromatic compounds, and transition metals. Various analytical techniques and cellular and molecular assays are applied to assess the redox activity of PM and the formation of reactive oxygen species. Multiphase chemical interactions of lung antioxidants with atmospheric pollutants are crucial to the mechanistic and molecular understanding of oxidative stress upon respiratory deposition. The role of distinct PM components in health impacts and mortality needs to be clarified by integrated research on various spatiotemporal scales for better evaluation and mitigation of aerosol effects on public health in the Anthropocene.