The effect of hydroxyapatite particle size on viscoelastic
properties and calcium release from a thermosensitive triblock
copolymer

J 2017

The effect of hydroxyapatite particle size on viscoelastic properties and calcium release from a thermosensitive triblock copolymer

CHAMRADOVA, I., L. VOJTOVA, K. CASTKOVA, P. DIVIS, Miroslav PETEREK et. al.

Základní údaje

Originální název

The effect of hydroxyapatite particle size on viscoelastic properties and calcium release from a thermosensitive triblock copolymer

Autoři

CHAMRADOVA, I. (203 Česká republika), L. VOJTOVA (203 Česká republika), K. CASTKOVA (203 Česká republika), P. DIVIS (203 Česká republika), Miroslav PETEREK (203 Česká republika, garant, domácí) a J. JANCAR (203 Česká republika)

Vydání

COLLOID AND POLYMER SCIENCE, NEW YORK, SPRINGER, 2017, 0303-402X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10403 Physical chemistry

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.967

Kód RIV

RIV/00216224:14740/17:00100465

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1007/s00396-016-3983-7

UT WoS

000392135800011

Klíčová slova anglicky

Polymer composites; Smart polymers; Rheology; Hydroxyapatite; Core-shell particles; Sol-gel transition

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 22. 3. 2018 14:43, Mgr. Pavla Foltynová, Ph.D.

Anotace

V originále

Well-defined "smart" injectable hydrogel based on hydrophilic poly(ethylene glycol) (PEG) and hydrophobic poly(lactic acid-co-glycolic acid) (PLA/PGA) copolymer (PLGA-PEG-PLGA) gelling at the body temperature was modified by bioactive hydroxyapatite (HAp) in the form of micro-, nano-, and core-shell particles (mu-HAp, n-HAp, and CS-x, respectively) to be applicable as calcium delivery system in bone regeneration. Viscoelastic moduli increased with HAp content as expected. Whereas systems containing mu-HAp or CS-x particles maintained two sol-gel and gel-sol phase transitions, the n-HAp containing system showed only one sol-gel phase transition due to the strong interactions between polymer chain and the n-HAp surface. In vitro, studies proved the controlled uniform release of calcium cations from both CS-x and n-HAp over the 9-day period without any initial burst release.

Návaznosti

LM2015043, projekt VaV

Název: Česká infrastruktura pro integrativní strukturní biologii (Akronym: CIISB)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Czech Infrastructure for Integrative Structural Biology

LQ1601, projekt VaV

Název: CEITEC 2020 (Akronym: CEITEC2020)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, CEITEC 2020

Citovat

CHAMRADOVA, I., L. VOJTOVA, K. CASTKOVA, P. DIVIS, Miroslav PETEREK a J. JANCAR. The effect of hydroxyapatite particle size on viscoelastic properties and calcium release from a thermosensitive triblock copolymer. COLLOID AND POLYMER SCIENCE. NEW YORK: SPRINGER, 2017, roč. 295, č. 1, s. 107-115. ISSN 0303-402X. Dostupné z: https://dx.doi.org/10.1007/s00396-016-3983-7.

@article{1412066,
   author = {Chamradova, I. and Vojtova, L. and Castkova, K. and Divis, P. and Peterek, Miroslav and Jancar, J.},
   article_location = {NEW YORK},
   article_number = {1},
   doi = {http://dx.doi.org/10.1007/s00396-016-3983-7},
   keywords = {Polymer composites; Smart polymers; Rheology; Hydroxyapatite; Core-shell particles; Sol-gel transition},
   language = {eng},
   issn = {0303-402X},
   journal = {COLLOID AND POLYMER SCIENCE},
   title = {The effect of hydroxyapatite particle size on viscoelastic properties and calcium release from a thermosensitive triblock copolymer},
   url = {https://link.springer.com/article/10.1007%2Fs00396-016-3983-7},
   volume = {295},
   year = {2017}
}

TY  - JOUR
ID  - 1412066
AU  - Chamradova, I. - Vojtova, L. - Castkova, K. - Divis, P. - Peterek, Miroslav - Jancar, J.
PY  - 2017
TI  - The effect of hydroxyapatite particle size on viscoelastic properties and calcium release from a thermosensitive triblock copolymer
JF  - COLLOID AND POLYMER SCIENCE
VL  - 295
IS  - 1
SP  - 107-115
EP  - 107-115
PB  - SPRINGER
SN  - 0303402X
KW  - Polymer composites
KW  - Smart polymers
KW  - Rheology
KW  - Hydroxyapatite
KW  - Core-shell particles
KW  - Sol-gel transition
UR  - https://link.springer.com/article/10.1007%2Fs00396-016-3983-7
L2  - https://link.springer.com/article/10.1007%2Fs00396-016-3983-7
N2  - Well-defined "smart" injectable hydrogel based on hydrophilic poly(ethylene glycol) (PEG) and hydrophobic poly(lactic acid-co-glycolic acid) (PLA/PGA) copolymer (PLGA-PEG-PLGA) gelling at the body temperature was modified by bioactive hydroxyapatite (HAp) in the form of micro-, nano-, and core-shell particles (mu-HAp, n-HAp, and CS-x, respectively) to be applicable as calcium delivery system in bone regeneration. Viscoelastic moduli increased with HAp content as expected. Whereas systems containing mu-HAp or CS-x particles maintained two sol-gel and gel-sol phase transitions, the n-HAp containing system showed only one sol-gel phase transition due to the strong interactions between polymer chain and the n-HAp surface. In vitro, studies proved the controlled uniform release of calcium cations from both CS-x and n-HAp over the 9-day period without any initial burst release.
ER  -

CHAMRADOVA, I., L. VOJTOVA, K. CASTKOVA, P. DIVIS, Miroslav PETEREK a J. JANCAR. The effect of hydroxyapatite particle size on viscoelastic properties and calcium release from a thermosensitive triblock copolymer. \textit{COLLOID AND POLYMER SCIENCE}. NEW YORK: SPRINGER, 2017, roč.~295, č.~1, s.~107-115. ISSN~0303-402X. Dostupné z: https://dx.doi.org/10.1007/s00396-016-3983-7.

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