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@article{1412066,
author = {Chamradova, I. and Vojtova, L. and Castkova, K. and Divis, P. and Peterek, Miroslav and Jancar, J.},
article_location = {NEW YORK},
article_number = {1},
doi = {http://dx.doi.org/10.1007/s00396-016-3983-7},
keywords = {Polymer composites; Smart polymers; Rheology; Hydroxyapatite; Core-shell particles; Sol-gel transition},
language = {eng},
issn = {0303-402X},
journal = {COLLOID AND POLYMER SCIENCE},
title = {The effect of hydroxyapatite particle size on viscoelastic properties and calcium release from a thermosensitive triblock copolymer},
url = {https://link.springer.com/article/10.1007%2Fs00396-016-3983-7},
volume = {295},
year = {2017}
}
TY - JOUR
ID - 1412066
AU - Chamradova, I. - Vojtova, L. - Castkova, K. - Divis, P. - Peterek, Miroslav - Jancar, J.
PY - 2017
TI - The effect of hydroxyapatite particle size on viscoelastic properties and calcium release from a thermosensitive triblock copolymer
JF - COLLOID AND POLYMER SCIENCE
VL - 295
IS - 1
SP - 107-115
EP - 107-115
PB - SPRINGER
SN - 0303402X
KW - Polymer composites
KW - Smart polymers
KW - Rheology
KW - Hydroxyapatite
KW - Core-shell particles
KW - Sol-gel transition
UR - https://link.springer.com/article/10.1007%2Fs00396-016-3983-7
L2 - https://link.springer.com/article/10.1007%2Fs00396-016-3983-7
N2 - Well-defined "smart" injectable hydrogel based on hydrophilic poly(ethylene glycol) (PEG) and hydrophobic poly(lactic acid-co-glycolic acid) (PLA/PGA) copolymer (PLGA-PEG-PLGA) gelling at the body temperature was modified by bioactive hydroxyapatite (HAp) in the form of micro-, nano-, and core-shell particles (mu-HAp, n-HAp, and CS-x, respectively) to be applicable as calcium delivery system in bone regeneration. Viscoelastic moduli increased with HAp content as expected. Whereas systems containing mu-HAp or CS-x particles maintained two sol-gel and gel-sol phase transitions, the n-HAp containing system showed only one sol-gel phase transition due to the strong interactions between polymer chain and the n-HAp surface. In vitro, studies proved the controlled uniform release of calcium cations from both CS-x and n-HAp over the 9-day period without any initial burst release.
ER -
CHAMRADOVA, I., L. VOJTOVA, K. CASTKOVA, P. DIVIS, Miroslav PETEREK a J. JANCAR. The effect of hydroxyapatite particle size on viscoelastic properties and calcium release from a thermosensitive triblock copolymer. \textit{COLLOID AND POLYMER SCIENCE}. NEW YORK: SPRINGER, 2017, roč.~295, č.~1, s.~107-115. ISSN~0303-402X. Dostupné z: https://dx.doi.org/10.1007/s00396-016-3983-7.
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