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@article{1412868, author = {Fathalla, Walid Mohamed and Pazdera, Pavel and ElandRayes, Samir and Ali, Ibrahim}, article_number = {14}, doi = {http://dx.doi.org/10.1016/j.tet.2018.02.033}, keywords = {1-AMINOPHOSPHONATES; HYDROXYPHOSPHONATES; ACTIVATION; INHIBITORS; RENIN}, language = {eng}, issn = {0040-4020}, journal = {Tetrahedron}, title = {Efficient synthesis of alpha-substituted-alpha-arylmethyl phosphonates using trichloroacetimidate C-C coupling method}, url = {http://dx.doi.org/10.1016/j.tet.2018.02.033}, volume = {74}, year = {2018} }
TY - JOUR ID - 1412868 AU - Fathalla, Walid Mohamed - Pazdera, Pavel - El-Rayes, Samir - Ali, Ibrahim PY - 2018 TI - Efficient synthesis of alpha-substituted-alpha-arylmethyl phosphonates using trichloroacetimidate C-C coupling method JF - Tetrahedron VL - 74 IS - 14 SP - 1681-1691 EP - 1681-1691 SN - 00404020 KW - 1-AMINOPHOSPHONATES KW - HYDROXYPHOSPHONATES KW - ACTIVATION KW - INHIBITORS KW - RENIN UR - http://dx.doi.org/10.1016/j.tet.2018.02.033 N2 - A simple convenient protocol for the synthesis of di-Et alpha,alpha-diaryl methylphosphonate derivs. 5a-f, 6b-f, 7a-f and 8a-f, di-Et alpha-alkenyl alpha-aryl methylphosphonates 9a-d and 10a-d and alpha-(oxoalkyl) alpha-aryl methylphosphonate 11a-d and 12a-d is described. Trichloroacetimidates 3a-d were treated with activated arenes, styrene, allyltrimethylsilane or silylenol ethers C-nucleophiles in the presence TMSOTf to afford the desired products in good yields and short reaction time. ER -
FATHALLA, Walid Mohamed, Pavel PAZDERA, Samir EL-RAYES a Ibrahim ALI. Efficient synthesis of alpha-substituted-alpha-arylmethyl phosphonates using trichloroacetimidate C-C coupling method. \textit{Tetrahedron}. 2018, roč.~74, č.~14, s.~1681-1691. ISSN~0040-4020. Dostupné z: https://dx.doi.org/10.1016/j.tet.2018.02.033.
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