The hidden function of egg white antimicrobials: egg weightdependent effects of avidin on avian embryo survival and hatchling phenotype

KRKAVCOVÁ, Eva, Jakub KREISINGER, Ludmila HYÁNKOVÁ, Pavel HYRŠL a Veronika JAVŮRKOVÁ. The hidden function of egg white antimicrobials: egg weightdependent effects of avidin on avian embryo survival and hatchling phenotype. Biology Open. 2018, roč. 7, č. 4, s. 1-9. ISSN 2046-6390. Dostupné z: https://dx.doi.org/10.1242/bio.031518.

Základní údaje

• Originální název: The hidden function of egg white antimicrobials: egg weightdependent effects of avidin on avian embryo survival and hatchling phenotype
• Název česky: The hidden function of egg white antimicrobials: egg weightdependent effects of avidin on avian embryo survival and hatchling phenotype
• Autoři: KRKAVCOVÁ, Eva (203 Česká republika), Jakub KREISINGER (203 Česká republika), Ludmila HYÁNKOVÁ (203 Česká republika), Pavel HYRŠL (203 Česká republika, domácí) a Veronika JAVŮRKOVÁ (garant).
• Vydání: Biology Open, 2018, 2046-6390.

Další údaje

• Originální jazyk: angličtina
• Typ výsledku: Článek v odborném periodiku
• Obor: 10600 1.6 Biological sciences
• Stát vydavatele: Velká Británie a Severní Irsko
• Utajení: není předmětem státního či obchodního tajemství
• Impakt faktor: Impact factor: 1.962
• Kód RIV: RIV/00216224:14310/18:00102685
• Organizační jednotka: Přírodovědecká fakulta
• Doi: http://dx.doi.org/10.1242/bio.031518
• UT WoS: 000430172200005
• Klíčová slova česky: avidin; imunita
• Klíčová slova anglicky: avidin; immunity

Anotace

Avidin is a key egg white antimicrobial protein with strong binding capacity for biotin, an essential growth and immune cell precursor. As such, it is assumed to have a pronounced, though still poorly explored, effect on hatchling phenotype. We tested the effect of experimentally increased egg white avidin concentration (AVIDIN+) on hatching success, chick morphology, post-hatching growth performance and innate immune function in a model bird, Japanese quail (Coturnix japonica). Probability of embryo survival in the late embryonic phase increased with increasing eggweight in control eggs, but not in AVIDIN+ eggs. Chicks hatching from lighter AVIDIN+ eggs had a shorter tarsus than chicks hatching fromheavier AVIDIN+ eggs. This suggests that an increase in egg white avidin favours embryo survival in lighter eggs during late embryogenesis, but at the expense of reduced structural body size. Plasma complement activity in 6-day-old AVIDIN+ chicks decreased with increasing body mass and tarsus length; the opposite was observed in control chicks, implying that the later post-hatching innate immune function of larger chicks was compromised by an increase in egg white avidin concentration. Here, we document an important role of egg white antimicrobials in maintenance of embryo viability, avian hatchling morphology and immune phenotype.

Anotace česky

Avidin is a key egg white antimicrobial protein with strong binding capacity for biotin, an essential growth and immune cell precursor. As such, it is assumed to have a pronounced, though still poorly explored, effect on hatchling phenotype. We tested the effect of experimentally increased egg white avidin concentration (AVIDIN+) on hatching success, chick morphology, post-hatching growth performance and innate immune function in a model bird, Japanese quail (Coturnix japonica). Probability of embryo survival in the late embryonic phase increased with increasing eggweight in control eggs, but not in AVIDIN+ eggs. Chicks hatching from lighter AVIDIN+ eggs had a shorter tarsus than chicks hatching fromheavier AVIDIN+ eggs. This suggests that an increase in egg white avidin favours embryo survival in lighter eggs during late embryogenesis, but at the expense of reduced structural body size. Plasma complement activity in 6-day-old AVIDIN+ chicks decreased with increasing body mass and tarsus length; the opposite was observed in control chicks, implying that the later post-hatching innate immune function of larger chicks was compromised by an increase in egg white avidin concentration. Here, we document an important role of egg white antimicrobials in maintenance of embryo viability, avian hatchling morphology and immune phenotype.