J 2018

Prehospital stroke scale (FAST PLUS Test) predicts patients with intracranial large vessel occlusion

VÁCLAVÍK, Daniel, Michal BAR, Lukáš KLEČKA, David HOLEŠ, Martin ČÁBAL et. al.

Základní údaje

Originální název

Prehospital stroke scale (FAST PLUS Test) predicts patients with intracranial large vessel occlusion

Autoři

VÁCLAVÍK, Daniel (203 Česká republika), Michal BAR (203 Česká republika, garant), Lukáš KLEČKA (203 Česká republika), David HOLEŠ (203 Česká republika), Martin ČÁBAL (203 Česká republika) a Robert MIKULÍK (203 Česká republika, domácí)

Vydání

Brain and Behavior, Hoboken, John Wiley and Sons Inc. 2018, 2162-3279

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30103 Neurosciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.072

Kód RIV

RIV/00216224:14110/18:00104208

Organizační jednotka

Lékařská fakulta

UT WoS

000445850000019

Klíčová slova anglicky

large vessel occlusion stroke; paramedics; triage test

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 10. 2. 2019 17:47, Soňa Böhmová

Anotace

V originále

Background and Purpose: Mechanical thrombectomy (MT) is indicated for the treatment of large vessel occlusion (LVO) stroke. MT should be provided as quickly as possible; therefore, a test identifying suspected LVO in the prehospitalization stage is needed to ensure direct transport to a comprehensive stroke center (CSC). We assume that patients with clinically severe hemiparesis have a high probability of LVO stroke. We modified the FAST test into the FAST PLUS test: The first part is the FAST test and the second part evaluates the presence of severe arm or leg motor deficit. This prospective multicenter study evaluates the specificity and sensitivity of the FAST PLUS test in detecting LVO stroke. Methods: Paramedics were trained through e-learning to conduct the FAST PLUS test. All prehospital suspected stroke patients who were administered the FAST PLUS test were included. Demographics, National Institutes of Health Stroke Scale (NIHSS) score, brain computed tomography (CT), and CT angiography (CTA) were recorded. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and receiver operating curve (ROC) area for LVO were calculated. Results: The study included 435 patients. LVO were found in 124 patients (28%). Sensitivity was 93%, specificity was 47%, PPV was 41%, NPV was 94%, and ROC area for ICA/MCA occlusion was 0.65. Intracerebral hemorrhage (ICH) was identified in 48 patients (11%). Conclusion: We found that the FAST PLUS test had a high sensitivity for LVO stroke. Of the 435 patients, 41% were all directly transported to a CSC based on positive FAST PLUS test scores and were potential candidates for MT.