Genetics of taste preferences: a pilot study focused on
students of Masaryk University

a 2018

Genetics of taste preferences: a pilot study focused on students of Masaryk University

NOVÁK, David, Kristián KROTKÝ, Veronika TKÁČOVÁ, Veronika VITOUCHOVÁ, Dávid KÖVÉR et. al.

Základní údaje

Originální název

Genetics of taste preferences: a pilot study focused on students of Masaryk University

Autoři

NOVÁK, David (203 Česká republika), Kristián KROTKÝ (703 Slovensko), Veronika TKÁČOVÁ (703 Slovensko), Veronika VITOUCHOVÁ (203 Česká republika), Dávid KÖVÉR (703 Slovensko), Michaela BARTOŠOVÁ (703 Slovensko), Martina KUKLETOVÁ (203 Česká republika), Lydie IZAKOVIČOVÁ HOLLÁ (203 Česká republika) a Petra BOŘILOVÁ LINHARTOVÁ (203 Česká republika, domácí)

Vydání

XIX. setkání biochemiků a molekulárních biologů, 2018

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30101 Human genetics

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/18:00101360

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

taste perception; taste preference; diet; gene polymorphism; dentistry; students

Změněno: 15. 1. 2019 12:18, doc. RNDr. Petra Bořilová Linhartová, Ph.D., MBA

Anotace

V originále

Background Taste perception is one of the sensory-mediated factors influencing dietary preferences and eating habits. Some taste perception phenotypes have simple monogenic inheritance, whereas others have complex genetic architecture. The aim of this study was to determinate eleven single nucleotide polymorphisms (SNPs) in several genes involved in taste perception (glucose transporter - GLUT, carbonic anhydrase - CA, sweet and bitter taste receptors - TASR) and compared them to corresponding data from a questionnaire focused on diet and taste preferences. Subjects and methods The study group comprised of 88 students of Masaryk University. We collected various demographic and clinical data, the subjects filled in a questionnaire regarding their taste and dietary preferences and were genotyped for SLC2A2 (GLUT2, rs5400), CA6 (rs17032907, rs2274327, rs2274328, rs2274333, rs11576766), TAS1R2 (rs35874116, rs12033832, rs9701796), and TAS2R38 (rs713598, rs1726866) SNPs by qPCR using TaqMan fluorescent assays. Results We found significant associations between the CA6 rs2274333 SNP and the sweet taste preference (p < 0.05), the TAS1R2 rs9701796 SNP and the sour taste preference (p < 0.01), and the TAS2R38 rs172686 SNP and the salty taste preference (p < 0.05). Furthermore, a positive correlation between body mass index and salty taste preference was observed (p = 0.01). Conclusions Our data support the findings that the complex genetic background of taste perception of an individual may impact their taste preferences, possibly influencing their eating habits and overall health. Future education aimed at dietary habits may consider not only socioeconomic and demographic determinants but also taste preferences rooted in genetic predispositions. Acknowledgements This study was supported by grants NV17-30439A, GACR GB14-37368G, project MUNI/A/1008/2017, and funds provided by the Faculty of Medicine MU to junior researcher Petra Borilova Linhartova.

Návaznosti

GB14-37368G, projekt VaV

Název: Centrum orofaciálního vývoje a regenerace

Investor: Grantová agentura ČR, Centrum orofaciálního vývoje a regenerace

MUNI/A/1008/2017, interní kód MU

Název: Etiopatogenetické aspekty, diagnostika a léčba vybraných onemocnění dutiny ústní

Investor: Masarykova univerzita, Etiopatogenetické aspekty, diagnostika a léčba vybraných onemocnění dutiny ústní, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

NV17-30439A, projekt VaV

Název: Moderní biotechnologické a behaviorální přístupy ve výzkumu zubního kazu a strategie jeho prevence

ROZV/24/LF/2018, interní kód MU

Název: LF - Příspěvek na IP 2108

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, LF - Příspěvek na IP 2108, Interní rozvojové projekty

Citovat

NOVÁK, David, Kristián KROTKÝ, Veronika TKÁČOVÁ, Veronika VITOUCHOVÁ, Dávid KÖVÉR, Michaela BARTOŠOVÁ, Martina KUKLETOVÁ, Lydie IZAKOVIČOVÁ HOLLÁ a Petra BOŘILOVÁ LINHARTOVÁ. Genetics of taste preferences: a pilot study focused on students of Masaryk University. In XIX. setkání biochemiků a molekulárních biologů. 2018.

@proceedings{1470209,
   author = {Novák, David and Krotký, Kristián and Tkáčová, Veronika and Vitouchová, Veronika and Kövér, Dávid and Bartošová, Michaela and Kukletová, Martina and Izakovičová Hollá, Lydie and Bořilová Linhartová, Petra},
   booktitle = {XIX. setkání biochemiků a molekulárních biologů},
   keywords = {taste perception; taste preference; diet; gene polymorphism; dentistry; students},
   language = {eng},
   title = {Genetics of taste preferences: a pilot study focused on students of Masaryk University},
   year = {2018}
}

TY  - CONF
ID  - 1470209
AU  - Novák, David - Krotký, Kristián - Tkáčová, Veronika - Vitouchová, Veronika - Kövér, Dávid - Bartošová, Michaela - Kukletová, Martina - Izakovičová Hollá, Lydie - Bořilová Linhartová, Petra
PY  - 2018
TI  - Genetics of taste preferences: a pilot study focused on students of Masaryk University
KW  - taste perception
KW  - taste preference
KW  - diet
KW  - gene polymorphism
KW  - dentistry
KW  - students
N2  - Background Taste perception is one of the sensory-mediated factors influencing dietary preferences and eating habits. Some taste perception phenotypes have simple monogenic inheritance, whereas others have complex genetic architecture. The aim of this study was to determinate eleven single nucleotide polymorphisms (SNPs) in several genes involved in taste perception (glucose transporter - GLUT, carbonic anhydrase - CA, sweet and bitter taste receptors - TASR) and compared them to corresponding data from a questionnaire focused on diet and taste preferences. Subjects and methods The study group comprised of 88 students of Masaryk University. We collected various demographic and clinical data, the subjects filled in a questionnaire regarding their taste and dietary preferences and were genotyped for SLC2A2 (GLUT2, rs5400), CA6 (rs17032907, rs2274327, rs2274328, rs2274333, rs11576766), TAS1R2 (rs35874116, rs12033832, rs9701796), and TAS2R38 (rs713598, rs1726866) SNPs by qPCR using TaqMan fluorescent assays. Results We found significant associations between the CA6 rs2274333 SNP and the sweet taste preference (p < 0.05), the TAS1R2 rs9701796 SNP and the sour taste preference (p < 0.01), and the TAS2R38 rs172686 SNP and the salty taste preference (p < 0.05). Furthermore, a positive correlation between body mass index and salty taste preference was observed (p = 0.01). Conclusions Our data support the findings that the complex genetic background of taste perception of an individual may impact their taste preferences, possibly influencing their eating habits and overall health. Future education aimed at dietary habits may consider not only socioeconomic and demographic determinants but also taste preferences rooted in genetic predispositions. Acknowledgements This study was supported by grants NV17-30439A, GACR GB14-37368G, project MUNI/A/1008/2017, and funds provided by the Faculty of Medicine MU to junior researcher Petra Borilova Linhartova.
ER  -

NOVÁK, David, Kristián KROTKÝ, Veronika TKÁČOVÁ, Veronika VITOUCHOVÁ, Dávid KÖVÉR, Michaela BARTOŠOVÁ, Martina KUKLETOVÁ, Lydie IZAKOVIČOVÁ HOLLÁ a Petra BOŘILOVÁ LINHARTOVÁ. Genetics of taste preferences: a pilot study focused on students of Masaryk University. In \textit{XIX. setkání biochemiků a molekulárních biologů}. 2018.

Podrobný výpis o publikaci