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@article{1479521, author = {Zigáčková, Dagmar and Vaňáčová, Štěpánka}, article_location = {LONDON}, article_number = {1762}, doi = {http://dx.doi.org/10.1098/rstb.2018.0171}, keywords = {RNA uridylation; tutase; RNA modification; RNA surveillance; RNA processing; RNA degradation}, language = {eng}, issn = {0962-8436}, journal = {PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES}, title = {The role of 3 ' end uridylation in RNA metabolism and cellular physiology}, url = {https://royalsocietypublishing.org/doi/10.1098/rstb.2018.0171}, volume = {373}, year = {2018} }
TY - JOUR ID - 1479521 AU - Zigáčková, Dagmar - Vaňáčová, Štěpánka PY - 2018 TI - The role of 3 ' end uridylation in RNA metabolism and cellular physiology JF - PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES VL - 373 IS - 1762 SP - 20180171 EP - 20180171 PB - ROYAL SOC SN - 09628436 KW - RNA uridylation KW - tutase KW - RNA modification KW - RNA surveillance KW - RNA processing KW - RNA degradation UR - https://royalsocietypublishing.org/doi/10.1098/rstb.2018.0171 N2 - Most eukaryotic RNAs are posttranscriptionally modified. The majority of modifications promote RNA maturation, others may regulate function and stability. The 3' terminal non-templated oligouridylation is a widespread modification affecting many cellular RNAs at some stage of their life cycle. It has diverse roles in RNA metabolism. The most prevalent is the regulation of stability and quality control. On the cellular and organismal level, it plays a critical role in a number of pathways, such as cell cycle regulation, cell death, development or viral infection. Defects in uridylation have been linked to several diseases. This review summarizes the current knowledge about the role of the 3' terminal oligo(U)-tailing in biology of various RNAs in eukaryotes and describes key factors involved in these pathways. This article is part of the theme issue '5' and 3' modifications controlling RNA degradation'. ER -
ZIGÁČKOVÁ, Dagmar and Štěpánka VAŇÁČOVÁ. The role of 3 ' end uridylation in RNA metabolism and cellular physiology. \textit{PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES}. LONDON: ROYAL SOC, 2018, vol.~373, No~1762, p.~20180171-20180184. ISSN~0962-8436. Available from: https://dx.doi.org/10.1098/rstb.2018.0171.
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