| ŠTACKO, Peter, Lucie MUCHOVA, Libor VITEK a Petr KLÁN. Visible to NIR Light Photoactivation of Hydrogen Sulfide for Biological Targeting. Organic Letters. WASHINGTON: American Chemical Society, 2018, roč. 20, č. 16, s. 4907-4911. ISSN 1523-7060. Dostupné z: https://dx.doi.org/10.1021/acs.orglett.8b02043. |
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@article{1488100,
author = {Štacko, Peter and Muchova, Lucie and Vitek, Libor and Klán, Petr},
article_location = {WASHINGTON},
article_number = {16},
doi = {http://dx.doi.org/10.1021/acs.orglett.8b02043},
keywords = {PHOTOREMOVABLE PROTECTING GROUPS; GASEOUS SIGNALING MOLECULE; PHOTODYNAMIC THERAPY; FLUORESCENT-PROBES; METHYLENE-BLUE; BODIPY DYES; GREEN-LIGHT; RELEASE; H2S; DERIVATIVES},
language = {eng},
issn = {1523-7060},
journal = {Organic Letters},
title = {Visible to NIR Light Photoactivation of Hydrogen Sulfide for Biological Targeting},
url = {https://pubs.acs.org/doi/10.1021/acs.orglett.8b02043},
volume = {20},
year = {2018}
}
TY - JOUR
ID - 1488100
AU - Štacko, Peter - Muchova, Lucie - Vitek, Libor - Klán, Petr
PY - 2018
TI - Visible to NIR Light Photoactivation of Hydrogen Sulfide for Biological Targeting
JF - Organic Letters
VL - 20
IS - 16
SP - 4907-4911
EP - 4907-4911
PB - American Chemical Society
SN - 15237060
KW - PHOTOREMOVABLE PROTECTING GROUPS
KW - GASEOUS SIGNALING MOLECULE
KW - PHOTODYNAMIC THERAPY
KW - FLUORESCENT-PROBES
KW - METHYLENE-BLUE
KW - BODIPY DYES
KW - GREEN-LIGHT
KW - RELEASE
KW - H2S
KW - DERIVATIVES
UR - https://pubs.acs.org/doi/10.1021/acs.orglett.8b02043
L2 - https://pubs.acs.org/doi/10.1021/acs.orglett.8b02043
N2 - The synthesis and photochemical properties of H2S-releasing BODIPY thiocarbamate photocage scaffolds activatable by visible-to-NIR (up to 700 nm) light to release carbonyl sulfide (COS), which is transformed to H2S using either isolated or natural carbonic anhydrase, is reported. The excellent uncaging cross section and high H2S release yields in in vitro experiments, including live-cell imaging, suggest that these photocages can serve as a platform for the bio-orthogonal phototriggered release within the tissue-transparent window.
ER -
ŠTACKO, Peter, Lucie MUCHOVA, Libor VITEK a Petr KLÁN. Visible to NIR Light Photoactivation of Hydrogen Sulfide for Biological Targeting. \textit{Organic Letters}. WASHINGTON: American Chemical Society, 2018, roč.~20, č.~16, s.~4907-4911. ISSN~1523-7060. Dostupné z: https://dx.doi.org/10.1021/acs.orglett.8b02043.
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