Haloalkane Dehalogenases From Marine Organisms

J 2018

Haloalkane Dehalogenases From Marine Organisms

KUNKA, Antonín; Jiří DAMBORSKÝ a Zbyněk PROKOP

Základní údaje

Originální název

Haloalkane Dehalogenases From Marine Organisms

Autoři

KUNKA, Antonín; Jiří DAMBORSKÝ a Zbyněk PROKOP

Vydání

MARINE ENZYMES AND SPECIALIZED METABOLISM, PT B, SAN DIEGO, ELSEVIER ACADEMIC PRESS INC, 2018, 0076-6879

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10608 Biochemistry and molecular biology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.862

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/18:00101755

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

BIOCHEMICAL-CHARACTERIZATION; GAMMA-HEXACHLOROCYCLOHEXANE; BRADYRHIZOBIUM-JAPONICUM; DEGRADING BACTERIUM; EXPERIMENTAL-DESIGN; COLORIMETRIC ASSAY; PROTEIN STABILITY; ACCESS TUNNELS; STEADY-STATE; GEN. NOV.

Změněno: 23. 4. 2024 14:23, Mgr. Michal Petr

Anotace

V originále

Haloalkane dehalogenases degrade halogenated compounds to corresponding alcohols by a hydrolytic mechanism. These enzymes are being intensively investigated as model systems in experimental and in silico studies of enzyme mechanism and evolution, but also hold importance as useful biocatalysts for a number of biotechnological applications. Haloalkane dehalogenases originate from various organisms including bacteria (degraders, symbionts, or pathogens), eukaryotes, and archaea. Several members of this enzyme family have been found in marine organisms. The marine environment represents a good source of enzymes with novel properties, because of its diverse living conditions. A number of novel dehalogenases isolated from marine environments show interesting characteristics such as high activity, unusually broad substrate specificity, stability, or selectivity. In this chapter, the overview of haloalkane dehalogenases from marine organisms is presented and their characteristics are summarized together with an overview of the methods for their identification and biochemical characterization.

Návaznosti

GA16-07965S, projekt VaV

Název: Řízená evoluce dynamických elementů v enzymech s využitím mikrofluidních čipů

Investor: Grantová agentura ČR, Řízená evoluce dynamických elementů v enzymech s využitím mikrofluidních čipů

LM2015047, projekt VaV

Název: Česká národní infrastruktura pro biologická data (Akronym: ELIXIR-CZ)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Česká národní infrastruktura pro biologická data

LM2015051, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX RI)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Výzkumná infrastruktura RECETOX

LM2015055, projekt VaV

Název: Centrum pro systémovou biologii (Akronym: C4SYS)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, The national infrastructure C4SYS - Centre for Systems Biology

LO1214, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Centrum pro výzkum toxických látek v prostředí

Citovat

KUNKA, Antonín; Jiří DAMBORSKÝ a Zbyněk PROKOP. Haloalkane Dehalogenases From Marine Organisms. MARINE ENZYMES AND SPECIALIZED METABOLISM, PT B. SAN DIEGO: ELSEVIER ACADEMIC PRESS INC, 2018, roč. 605, č. 1, s. 203-251. ISSN 0076-6879. Dostupné z: https://doi.org/10.1016/bs.mie.2018.03.005.

@article{1503356,
   author = {Kunka, Antonín and Damborský, Jiří and Prokop, Zbyněk},
   article_location = {SAN DIEGO},
   article_number = {1},
   doi = {https://doi.org/10.1016/bs.mie.2018.03.005},
   keywords = {BIOCHEMICAL-CHARACTERIZATION; GAMMA-HEXACHLOROCYCLOHEXANE; BRADYRHIZOBIUM-JAPONICUM; DEGRADING BACTERIUM; EXPERIMENTAL-DESIGN; COLORIMETRIC ASSAY; PROTEIN STABILITY; ACCESS TUNNELS; STEADY-STATE; GEN. NOV.},
   language = {eng},
   issn = {0076-6879},
   journal = {MARINE ENZYMES AND SPECIALIZED METABOLISM, PT B},
   title = {Haloalkane Dehalogenases From Marine Organisms},
   url = {http://dx.doi.org/10.1016/bs.mie.2018.03.005},
   volume = {605},
   year = {2018}
}

TY  - JOUR
ID  - 1503356
AU  - Kunka, Antonín - Damborský, Jiří - Prokop, Zbyněk
PY  - 2018
TI  - Haloalkane Dehalogenases From Marine Organisms
JF  - MARINE ENZYMES AND SPECIALIZED METABOLISM, PT B
VL  - 605
IS  - 1
SP  - 203-251
EP  - 203-251
PB  - ELSEVIER ACADEMIC PRESS INC
SN  - 00766879
KW  - BIOCHEMICAL-CHARACTERIZATION
KW  - GAMMA-HEXACHLOROCYCLOHEXANE
KW  - BRADYRHIZOBIUM-JAPONICUM
KW  - DEGRADING BACTERIUM
KW  - EXPERIMENTAL-DESIGN
KW  - COLORIMETRIC ASSAY
KW  - PROTEIN STABILITY
KW  - ACCESS TUNNELS
KW  - STEADY-STATE
KW  - GEN. NOV.
UR  - http://dx.doi.org/10.1016/bs.mie.2018.03.005
N2  - Haloalkane dehalogenases degrade halogenated compounds to corresponding alcohols by a hydrolytic mechanism. These enzymes are being intensively investigated as model systems in experimental and in silico studies of enzyme mechanism and evolution, but also hold importance as useful biocatalysts for a number of biotechnological applications. Haloalkane dehalogenases originate from various organisms including bacteria (degraders, symbionts, or pathogens), eukaryotes, and archaea. Several members of this enzyme family have been found in marine organisms. The marine environment represents a good source of enzymes with novel properties, because of its diverse living conditions. A number of novel dehalogenases isolated from marine environments show interesting characteristics such as high activity, unusually broad substrate specificity, stability, or selectivity. In this chapter, the overview of haloalkane dehalogenases from marine organisms is presented and their characteristics are summarized together with an overview of the methods for their identification and biochemical characterization.
ER  -

KUNKA, Antonín; Jiří DAMBORSKÝ a Zbyněk PROKOP. Haloalkane Dehalogenases From Marine Organisms. \textit{MARINE ENZYMES AND SPECIALIZED METABOLISM, PT B}. SAN DIEGO: ELSEVIER ACADEMIC PRESS INC, 2018, roč.~605, č.~1, s.~203-251. ISSN~0076-6879. Dostupné z: https://doi.org/10.1016/bs.mie.2018.03.005.

Přehled o publikaci