Prognostic Accuracy of Three COPD Classification Systems in
Relation to Long-Term Mortality of COPD Patients: A Prospective
Multicenter Study

J 2019

Prognostic Accuracy of Three COPD Classification Systems in Relation to Long-Term Mortality of COPD Patients: A Prospective Multicenter Study

PLUTINSKÝ, Marek; Kristián BRAT; Michal SVOBODA; Jaromir ZATLOUKAL; Patricie POPELKOVA et al.

Základní údaje

Originální název

Prognostic Accuracy of Three COPD Classification Systems in Relation to Long-Term Mortality of COPD Patients: A Prospective Multicenter Study

Autoři

PLUTINSKÝ, Marek; Kristián BRAT; Michal SVOBODA; Jaromir ZATLOUKAL; Patricie POPELKOVA a Vladimir KOBLIZEK

Vydání

LUNG, NEW YORK, SPRINGER, 2019, 0341-2040

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30203 Respiratory systems

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.817

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/19:00109670

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

COPD; GOLD classification; Prognosis; Mortality

Štítky

14110215, 14119612, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 16. 5. 2019 14:44, Soňa Böhmová

Anotace

V originále

Recent research showed group B patients express higher mortality compared to group C patients when GOLD A-D grouping is used. We aimed to compare the prognostic accuracy of three GOLD classification systems, I-IV (pre-2011), A-D (2011-2016) and A-D (2017-present) in relation to mortality, exacerbation risk, quality of life (QoL) assessment and specific treatments use in a real-life COPD cohort. We used the data of 720 patients from the Czech Multicenter Research Database of COPD. Four-year mortality and time-to-exacerbation using the GOLD pre-2011, 2011-2016 and 2017-present classification schemes were assessed. Moreover, distribution of specific treatments use and QoL measures were analyzed. The GOLD I-IV classification system showed gradual increase in 4-year mortality across the stages (GOLD II 18.8%, III 28.5%, IV 38.7%) (p=0.001). Using the A-D 2011-2016 classification scheme, group C patients had lower mortality (16.7%) than group B (18.7%) (p=0.009). The A-D 2017-present classification showed higher mortality in group B (25.5%) compared to group C (20%) (p=0.05). For additional outcomes, the GOLD I-IV scheme showed highest match between the calculated 4-year exacerbation risk and QoL measures and GOLD stage/grouping. In terms of specific treatment distributions, various patterns for each GOLD classification system were observed with best match of GOLD 2017-present system to the layout of GOLD groups and categories. We conclude the GOLD I-IV classification system had the highest accuracy related to mortality, QoL measures and exacerbation risk prediction, while the A-D 2017-present scheme was most accurate within severity of symptoms prediction reflected also by more frequent specific treatments use.

Citovat

PLUTINSKÝ, Marek; Kristián BRAT; Michal SVOBODA; Jaromir ZATLOUKAL; Patricie POPELKOVA a Vladimir KOBLIZEK. Prognostic Accuracy of Three COPD Classification Systems in Relation to Long-Term Mortality of COPD Patients: A Prospective Multicenter Study. LUNG. NEW YORK: SPRINGER, 2019, roč. 197, č. 2, s. 173-179. ISSN 0341-2040. Dostupné z: https://doi.org/10.1007/s00408-019-00196-6.

@article{1531402,
   author = {Plutinský, Marek and Brat, Kristián and Svoboda, Michal and Zatloukal, Jaromir and Popelkova, Patricie and Koblizek, Vladimir},
   article_location = {NEW YORK},
   article_number = {2},
   doi = {https://doi.org/10.1007/s00408-019-00196-6},
   keywords = {COPD; GOLD classification; Prognosis; Mortality},
   language = {eng},
   issn = {0341-2040},
   journal = {LUNG},
   title = {Prognostic Accuracy of Three COPD Classification Systems in Relation to Long-Term Mortality of COPD Patients: A Prospective Multicenter Study},
   url = {http://dx.doi.org/10.1007/s00408-019-00196-6},
   volume = {197},
   year = {2019}
}

TY  - JOUR
ID  - 1531402
AU  - Plutinský, Marek - Brat, Kristián - Svoboda, Michal - Zatloukal, Jaromir - Popelkova, Patricie - Koblizek, Vladimir
PY  - 2019
TI  - Prognostic Accuracy of Three COPD Classification Systems in Relation to Long-Term Mortality of COPD Patients: A Prospective Multicenter Study
JF  - LUNG
VL  - 197
IS  - 2
SP  - 173-179
EP  - 173-179
PB  - SPRINGER
SN  - 03412040
KW  - COPD
KW  - GOLD classification
KW  - Prognosis
KW  - Mortality
UR  - http://dx.doi.org/10.1007/s00408-019-00196-6
L2  - http://dx.doi.org/10.1007/s00408-019-00196-6
N2  - Recent research showed group B patients express higher mortality compared to group C patients when GOLD A-D grouping is used. We aimed to compare the prognostic accuracy of three GOLD classification systems, I-IV (pre-2011), A-D (2011-2016) and A-D (2017-present) in relation to mortality, exacerbation risk, quality of life (QoL) assessment and specific treatments use in a real-life COPD cohort. We used the data of 720 patients from the Czech Multicenter Research Database of COPD. Four-year mortality and time-to-exacerbation using the GOLD pre-2011, 2011-2016 and 2017-present classification schemes were assessed. Moreover, distribution of specific treatments use and QoL measures were analyzed. The GOLD I-IV classification system showed gradual increase in 4-year mortality across the stages (GOLD II 18.8%, III 28.5%, IV 38.7%) (p=0.001). Using the A-D 2011-2016 classification scheme, group C patients had lower mortality (16.7%) than group B (18.7%) (p=0.009). The A-D 2017-present classification showed higher mortality in group B (25.5%) compared to group C (20%) (p=0.05). For additional outcomes, the GOLD I-IV scheme showed highest match between the calculated 4-year exacerbation risk and QoL measures and GOLD stage/grouping. In terms of specific treatment distributions, various patterns for each GOLD classification system were observed with best match of GOLD 2017-present system to the layout of GOLD groups and categories. We conclude the GOLD I-IV classification system had the highest accuracy related to mortality, QoL measures and exacerbation risk prediction, while the A-D 2017-present scheme was most accurate within severity of symptoms prediction reflected also by more frequent specific treatments use.
ER  -

PLUTINSKÝ, Marek; Kristián BRAT; Michal SVOBODA; Jaromir ZATLOUKAL; Patricie POPELKOVA a Vladimir KOBLIZEK. Prognostic Accuracy of Three COPD Classification Systems in Relation to Long-Term Mortality of COPD Patients: A Prospective Multicenter Study. \textit{LUNG}. NEW YORK: SPRINGER, 2019, roč.~197, č.~2, s.~173-179. ISSN~0341-2040. Dostupné z: https://doi.org/10.1007/s00408-019-00196-6.

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