Prognostic Accuracy of Three COPD Classification Systems in
Relation to Long-Term Mortality of COPD Patients: A Prospective
Multicenter Study

J 2019

Prognostic Accuracy of Three COPD Classification Systems in Relation to Long-Term Mortality of COPD Patients: A Prospective Multicenter Study

PLUTINSKÝ, Marek, Kristián BRAT, Michal SVOBODA, Jaromir ZATLOUKAL, Patricie POPELKOVA et. al.

Základní údaje

Originální název

Prognostic Accuracy of Three COPD Classification Systems in Relation to Long-Term Mortality of COPD Patients: A Prospective Multicenter Study

Autoři

PLUTINSKÝ, Marek (703 Slovensko, domácí), Kristián BRAT (703 Slovensko, garant, domácí), Michal SVOBODA (203 Česká republika, domácí), Jaromir ZATLOUKAL (203 Česká republika), Patricie POPELKOVA (203 Česká republika) a Vladimir KOBLIZEK (203 Česká republika)

Vydání

LUNG, NEW YORK, SPRINGER, 2019, 0341-2040

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30203 Respiratory systems

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.817

Kód RIV

RIV/00216224:14110/19:00109670

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1007/s00408-019-00196-6

UT WoS

000466205900009

Klíčová slova anglicky

COPD; GOLD classification; Prognosis; Mortality

Štítky

14110215, 14119612, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 16. 5. 2019 14:44, Soňa Böhmová

Anotace

V originále

Recent research showed group B patients express higher mortality compared to group C patients when GOLD A-D grouping is used. We aimed to compare the prognostic accuracy of three GOLD classification systems, I-IV (pre-2011), A-D (2011-2016) and A-D (2017-present) in relation to mortality, exacerbation risk, quality of life (QoL) assessment and specific treatments use in a real-life COPD cohort. We used the data of 720 patients from the Czech Multicenter Research Database of COPD. Four-year mortality and time-to-exacerbation using the GOLD pre-2011, 2011-2016 and 2017-present classification schemes were assessed. Moreover, distribution of specific treatments use and QoL measures were analyzed. The GOLD I-IV classification system showed gradual increase in 4-year mortality across the stages (GOLD II 18.8%, III 28.5%, IV 38.7%) (p=0.001). Using the A-D 2011-2016 classification scheme, group C patients had lower mortality (16.7%) than group B (18.7%) (p=0.009). The A-D 2017-present classification showed higher mortality in group B (25.5%) compared to group C (20%) (p=0.05). For additional outcomes, the GOLD I-IV scheme showed highest match between the calculated 4-year exacerbation risk and QoL measures and GOLD stage/grouping. In terms of specific treatment distributions, various patterns for each GOLD classification system were observed with best match of GOLD 2017-present system to the layout of GOLD groups and categories. We conclude the GOLD I-IV classification system had the highest accuracy related to mortality, QoL measures and exacerbation risk prediction, while the A-D 2017-present scheme was most accurate within severity of symptoms prediction reflected also by more frequent specific treatments use.

Citovat

PLUTINSKÝ, Marek, Kristián BRAT, Michal SVOBODA, Jaromir ZATLOUKAL, Patricie POPELKOVA a Vladimir KOBLIZEK. Prognostic Accuracy of Three COPD Classification Systems in Relation to Long-Term Mortality of COPD Patients: A Prospective Multicenter Study. LUNG. NEW YORK: SPRINGER, 2019, roč. 197, č. 2, s. 173-179. ISSN 0341-2040. Dostupné z: https://dx.doi.org/10.1007/s00408-019-00196-6.

@article{1531402,
   author = {Plutinský, Marek and Brat, Kristián and Svoboda, Michal and Zatloukal, Jaromir and Popelkova, Patricie and Koblizek, Vladimir},
   article_location = {NEW YORK},
   article_number = {2},
   doi = {http://dx.doi.org/10.1007/s00408-019-00196-6},
   keywords = {COPD; GOLD classification; Prognosis; Mortality},
   language = {eng},
   issn = {0341-2040},
   journal = {LUNG},
   title = {Prognostic Accuracy of Three COPD Classification Systems in Relation to Long-Term Mortality of COPD Patients: A Prospective Multicenter Study},
   url = {http://dx.doi.org/10.1007/s00408-019-00196-6},
   volume = {197},
   year = {2019}
}

TY  - JOUR
ID  - 1531402
AU  - Plutinský, Marek - Brat, Kristián - Svoboda, Michal - Zatloukal, Jaromir - Popelkova, Patricie - Koblizek, Vladimir
PY  - 2019
TI  - Prognostic Accuracy of Three COPD Classification Systems in Relation to Long-Term Mortality of COPD Patients: A Prospective Multicenter Study
JF  - LUNG
VL  - 197
IS  - 2
SP  - 173-179
EP  - 173-179
PB  - SPRINGER
SN  - 03412040
KW  - COPD
KW  - GOLD classification
KW  - Prognosis
KW  - Mortality
UR  - http://dx.doi.org/10.1007/s00408-019-00196-6
L2  - http://dx.doi.org/10.1007/s00408-019-00196-6
N2  - Recent research showed group B patients express higher mortality compared to group C patients when GOLD A-D grouping is used. We aimed to compare the prognostic accuracy of three GOLD classification systems, I-IV (pre-2011), A-D (2011-2016) and A-D (2017-present) in relation to mortality, exacerbation risk, quality of life (QoL) assessment and specific treatments use in a real-life COPD cohort. We used the data of 720 patients from the Czech Multicenter Research Database of COPD. Four-year mortality and time-to-exacerbation using the GOLD pre-2011, 2011-2016 and 2017-present classification schemes were assessed. Moreover, distribution of specific treatments use and QoL measures were analyzed. The GOLD I-IV classification system showed gradual increase in 4-year mortality across the stages (GOLD II 18.8%, III 28.5%, IV 38.7%) (p=0.001). Using the A-D 2011-2016 classification scheme, group C patients had lower mortality (16.7%) than group B (18.7%) (p=0.009). The A-D 2017-present classification showed higher mortality in group B (25.5%) compared to group C (20%) (p=0.05). For additional outcomes, the GOLD I-IV scheme showed highest match between the calculated 4-year exacerbation risk and QoL measures and GOLD stage/grouping. In terms of specific treatment distributions, various patterns for each GOLD classification system were observed with best match of GOLD 2017-present system to the layout of GOLD groups and categories. We conclude the GOLD I-IV classification system had the highest accuracy related to mortality, QoL measures and exacerbation risk prediction, while the A-D 2017-present scheme was most accurate within severity of symptoms prediction reflected also by more frequent specific treatments use.
ER  -

PLUTINSKÝ, Marek, Kristián BRAT, Michal SVOBODA, Jaromir ZATLOUKAL, Patricie POPELKOVA a Vladimir KOBLIZEK. Prognostic Accuracy of Three COPD Classification Systems in Relation to Long-Term Mortality of COPD Patients: A Prospective Multicenter Study. \textit{LUNG}. NEW YORK: SPRINGER, 2019, roč.~197, č.~2, s.~173-179. ISSN~0341-2040. Dostupné z: https://dx.doi.org/10.1007/s00408-019-00196-6.

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