Markers of Atherosclerosis. Part 2, Genetic and Imaging Markers

J 2019

Markers of Atherosclerosis. Part 2, Genetic and Imaging Markers

TIBAUT, Miha; Martin CAPRNDA; Peter KUBATKA; Andreja SINKOVIC; Vanda VALENTOVA et al.

Základní údaje

Originální název

Markers of Atherosclerosis. Part 2, Genetic and Imaging Markers

Autoři

Vydání

HEART LUNG AND CIRCULATION, NEW YORK, ELSEVIER SCIENCE INC, 2019, 1443-9506

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.194

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/19:00108496

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Biomarkers; Atherosclerosis; Genetic polymorphism; Imaging biomarkers; Carotid intima media thickness; Micro RNA

Štítky

14110121, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 16. 7. 2019 16:15, Soňa Böhmová

Anotace

V originále

This is Part 2 of a two-part review summarising current knowledge on biomarkers of atherosclerosis. Part 1 addressed serological biomarkers. Here, in part 2 we address genetic and imaging markers, and other developments in predicting risk. Further improvements in risk stratification are expected with the addition of genetic risk scores. In addition to single nucleotide polymorphisms (SNPs), recent advances in epigenetics offer DNA methylation profiles, histone chemical modifications, and micro-RNAs as other promising indicators of atherosclerosis. Imaging biomarkers are better studied and already have a higher degree of clinical applicability in cardiovascular (CV) event prediction and detection of preclinical atherosclerosis. With new methodologies, such as proteomics and metabolomics, discoveries of new clinically applicable biomarkers are expected.

Návaznosti

NV17-29701A, projekt VaV

Název: Ischémií modifikovaný albumin a cirkulující mikroRNA jako nové technologie k monitorování tkáňové ischémie po cévních rekonstrukcích na břišní aortě

Citovat

TIBAUT, Miha; Martin CAPRNDA; Peter KUBATKA; Andreja SINKOVIC; Vanda VALENTOVA; Slavomira FILIPOVA; Katarina GAZDIKOVA; Ludovit GASPAR; Ioana MOZOS; Emmanuel E. EGOM; Luis RODRIGO; Peter KRUŽLIAK a Daniel PETROVIC. Markers of Atherosclerosis. Part 2, Genetic and Imaging Markers. HEART LUNG AND CIRCULATION. NEW YORK: ELSEVIER SCIENCE INC, 2019, roč. 28, č. 5, s. 678-689. ISSN 1443-9506. Dostupné z: https://doi.org/10.1016/j.hlc.2018.09.006.

@article{1545972,
   author = {Tibaut, Miha and Caprnda, Martin and Kubatka, Peter and Sinkovic, Andreja and Valentova, Vanda and Filipova, Slavomira and Gazdikova, Katarina and Gaspar, Ludovit and Mozos, Ioana and Egom, Emmanuel E. and Rodrigo, Luis and Kružliak, Peter and Petrovic, Daniel},
   article_location = {NEW YORK},
   article_number = {5},
   doi = {https://doi.org/10.1016/j.hlc.2018.09.006},
   keywords = {Biomarkers; Atherosclerosis; Genetic polymorphism; Imaging biomarkers; Carotid intima media thickness; Micro RNA},
   language = {eng},
   issn = {1443-9506},
   journal = {HEART LUNG AND CIRCULATION},
   title = {Markers of Atherosclerosis. Part 2, Genetic and Imaging Markers},
   url = {http://dx.doi.org/10.1016/j.hlc.2018.09.006},
   volume = {28},
   year = {2019}
}

TY  - JOUR
ID  - 1545972
AU  - Tibaut, Miha - Caprnda, Martin - Kubatka, Peter - Sinkovic, Andreja - Valentova, Vanda - Filipova, Slavomira - Gazdikova, Katarina - Gaspar, Ludovit - Mozos, Ioana - Egom, Emmanuel E. - Rodrigo, Luis - Kružliak, Peter - Petrovic, Daniel
PY  - 2019
TI  - Markers of Atherosclerosis. Part 2, Genetic and Imaging Markers
JF  - HEART LUNG AND CIRCULATION
VL  - 28
IS  - 5
SP  - 678-689
EP  - 678-689
PB  - ELSEVIER SCIENCE INC
SN  - 14439506
KW  - Biomarkers
KW  - Atherosclerosis
KW  - Genetic polymorphism
KW  - Imaging biomarkers
KW  - Carotid intima media thickness
KW  - Micro RNA
UR  - http://dx.doi.org/10.1016/j.hlc.2018.09.006
L2  - http://dx.doi.org/10.1016/j.hlc.2018.09.006
N2  - This is Part 2 of a two-part review summarising current knowledge on biomarkers of atherosclerosis. Part 1 addressed serological biomarkers. Here, in part 2 we address genetic and imaging markers, and other developments in predicting risk. Further improvements in risk stratification are expected with the addition of genetic risk scores. In addition to single nucleotide polymorphisms (SNPs), recent advances in epigenetics offer DNA methylation profiles, histone chemical modifications, and micro-RNAs as other promising indicators of atherosclerosis. Imaging biomarkers are better studied and already have a higher degree of clinical applicability in cardiovascular (CV) event prediction and detection of preclinical atherosclerosis. With new methodologies, such as proteomics and metabolomics, discoveries of new clinically applicable biomarkers are expected.
ER  -

TIBAUT, Miha; Martin CAPRNDA; Peter KUBATKA; Andreja SINKOVIC; Vanda VALENTOVA; Slavomira FILIPOVA; Katarina GAZDIKOVA; Ludovit GASPAR; Ioana MOZOS; Emmanuel E. EGOM; Luis RODRIGO; Peter KRUŽLIAK a Daniel PETROVIC. Markers of Atherosclerosis. Part 2, Genetic and Imaging Markers. \textit{HEART LUNG AND CIRCULATION}. NEW YORK: ELSEVIER SCIENCE INC, 2019, roč.~28, č.~5, s.~678-689. ISSN~1443-9506. Dostupné z: https://doi.org/10.1016/j.hlc.2018.09.006.

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