Clostridium difficile infection and colonisation in children
under 3 years of age: prospective comparative study

J 2019

Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study

MUSIL, Václav; Lukáš HOMOLA; M. VRBA; Adriana BRAUNOVÁ; Tamara KRAVALOVÁ et al.

Základní údaje

Originální název

Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study

Autoři

MUSIL, Václav; Lukáš HOMOLA; M. VRBA; Adriana BRAUNOVÁ; Tamara KRAVALOVÁ; Miriam MALÁ a Lenka KRBKOVÁ

Vydání

Čs. epidemiologie, mikrobiologie, imunologie, Praha, ČSL JEP, 2019, 1210-7913

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30303 Infectious Diseases

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 0.379

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/19:00110557

Organizační jednotka

Lékařská fakulta

UT WoS

000480382600001

EID Scopus

2-s2.0-85071281962

Klíčová slova anglicky

infants; neonates; Clostridium dlifklle; diarrhoea; paediatrics; colonisation

Štítky

14110318, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 14. 4. 2020 14:20, Mgr. Tereza Miškechová

Anotace

V originále

Aims: Despite an increasing trend in Clostridium difficile infections (CDI) and high C difficile colonization rate especially among younger children. infants remain quite resistant to the disease. The goals of this study were to distinguish whether there exists a difference in CDI between children with or without diarrhoea, ascertain the prevalence of CDI, and assess CDI severity in children under 3 years with diarrhoea in our institution. Methods: A prospective study was conducted from May 2015 to June 2016. Children 3 years of age or younger were enrolled and into two groups. Every faecal sample was tested using a diagnostic two step screening algorithm including an immunochromatographic test and polymerase chain reaction. Results: The study enrolled 147 children with diarrhoea and 75 control patients. I he prevalence of CDI in children with diarrhoea was 2% (3/147), the prevalence of toxigenic C. difficile in the diarrhoeal group compared to the control group was 11.6 % (17/147) vs. 10.6% (8/75) (p < 0.9999). Conclusions: No significant difference was observed between infants with diarrhoea and the control group. We recommend not examining for C. difficile children not exhibiting specific risk factors.

Návaznosti

MUNI/A/1172/2015, interní kód MU

Název: Clostridium difficile u dětí (Akronym: CDPED)

Investor: Masarykova univerzita, Clostridium difficile u dětí, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

MUSIL, Václav; Lukáš HOMOLA; M. VRBA; Adriana BRAUNOVÁ; Tamara KRAVALOVÁ; Miriam MALÁ a Lenka KRBKOVÁ. Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study. Čs. epidemiologie, mikrobiologie, imunologie. Praha: ČSL JEP, 2019, roč. 68, č. 2, s. 59-64. ISSN 1210-7913.

@article{1551818,
   author = {Musil, Václav and Homola, Lukáš and Vrba, M. and Braunová, Adriana and Kravalová, Tamara and Malá, Miriam and Krbková, Lenka},
   article_location = {Praha},
   article_number = {2},
   keywords = {infants; neonates; Clostridium dlifklle; diarrhoea; paediatrics; colonisation},
   language = {eng},
   issn = {1210-7913},
   journal = {Čs. epidemiologie, mikrobiologie, imunologie},
   title = {Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study},
   url = {https://www.ncbi.nlm.nih.gov/pubmed/31398977},
   volume = {68},
   year = {2019}
}

TY  - JOUR
ID  - 1551818
AU  - Musil, Václav - Homola, Lukáš - Vrba, M. - Braunová, Adriana - Kravalová, Tamara - Malá, Miriam - Krbková, Lenka
PY  - 2019
TI  - Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study
JF  - Čs. epidemiologie, mikrobiologie, imunologie
VL  - 68
IS  - 2
SP  - 59-64
EP  - 59-64
PB  - ČSL JEP
SN  - 12107913
KW  - infants
KW  - neonates
KW  - Clostridium dlifklle
KW  - diarrhoea
KW  - paediatrics
KW  - colonisation
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31398977
L2  - https://www.ncbi.nlm.nih.gov/pubmed/31398977
N2  - Aims: Despite an increasing trend in Clostridium difficile infections (CDI) and high C difficile colonization rate especially among younger children. infants remain quite resistant to the disease. The goals of this study were to distinguish whether there exists a difference in CDI between children with or without diarrhoea, ascertain the prevalence of CDI, and assess CDI severity in children under 3 years with diarrhoea in our institution. Methods: A prospective study was conducted from May 2015 to June 2016. Children 3 years of age or younger were enrolled and into two groups. Every faecal sample was tested using a diagnostic two step screening algorithm including an immunochromatographic test and polymerase chain reaction. Results: The study enrolled 147 children with diarrhoea and 75 control patients. I he prevalence of CDI in children with diarrhoea was 2% (3/147), the prevalence of toxigenic C. difficile in the diarrhoeal group compared to the control group was 11.6 % (17/147) vs. 10.6% (8/75) (p < 0.9999). Conclusions: No significant difference was observed between infants with diarrhoea and the control group. We recommend not examining for C. difficile children not exhibiting specific risk factors.
ER  -

MUSIL, Václav; Lukáš HOMOLA; M. VRBA; Adriana BRAUNOVÁ; Tamara KRAVALOVÁ; Miriam MALÁ a Lenka KRBKOVÁ. Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study. \textit{Čs. epidemiologie, mikrobiologie, imunologie}. Praha: ČSL JEP, 2019, roč.~68, č.~2, s.~59-64. ISSN~1210-7913.

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