Clostridium difficile infection and colonisation in children
under 3 years of age: prospective comparative study

J 2019

Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study

MUSIL, Václav, Lukáš HOMOLA, M. VRBA, Adriana BRAUNOVÁ, Tamara KRAVALOVÁ et. al.

Základní údaje

Originální název

Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study

Autoři

MUSIL, Václav (203 Česká republika, garant, domácí), Lukáš HOMOLA (203 Česká republika, domácí), M. VRBA (203 Česká republika), Adriana BRAUNOVÁ (203 Česká republika, domácí), Tamara KRAVALOVÁ (203 Česká republika, domácí), Miriam MALÁ (203 Česká republika, domácí) a Lenka KRBKOVÁ (203 Česká republika, domácí)

Vydání

Čs. epidemiologie, mikrobiologie, imunologie, Praha, ČSL JEP, 2019, 1210-7913

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30303 Infectious Diseases

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 0.379

Kód RIV

RIV/00216224:14110/19:00110557

Organizační jednotka

Lékařská fakulta

UT WoS

000480382600001

Klíčová slova anglicky

infants; neonates; Clostridium dlifklle; diarrhoea; paediatrics; colonisation

Štítky

14110318, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 14. 4. 2020 14:20, Mgr. Tereza Miškechová

Anotace

V originále

Aims: Despite an increasing trend in Clostridium difficile infections (CDI) and high C difficile colonization rate especially among younger children. infants remain quite resistant to the disease. The goals of this study were to distinguish whether there exists a difference in CDI between children with or without diarrhoea, ascertain the prevalence of CDI, and assess CDI severity in children under 3 years with diarrhoea in our institution. Methods: A prospective study was conducted from May 2015 to June 2016. Children 3 years of age or younger were enrolled and into two groups. Every faecal sample was tested using a diagnostic two step screening algorithm including an immunochromatographic test and polymerase chain reaction. Results: The study enrolled 147 children with diarrhoea and 75 control patients. I he prevalence of CDI in children with diarrhoea was 2% (3/147), the prevalence of toxigenic C. difficile in the diarrhoeal group compared to the control group was 11.6 % (17/147) vs. 10.6% (8/75) (p < 0.9999). Conclusions: No significant difference was observed between infants with diarrhoea and the control group. We recommend not examining for C. difficile children not exhibiting specific risk factors.

Návaznosti

MUNI/A/1172/2015, interní kód MU

Název: Clostridium difficile u dětí (Akronym: CDPED)

Investor: Masarykova univerzita, Clostridium difficile u dětí, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

MUSIL, Václav, Lukáš HOMOLA, M. VRBA, Adriana BRAUNOVÁ, Tamara KRAVALOVÁ, Miriam MALÁ a Lenka KRBKOVÁ. Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study. Čs. epidemiologie, mikrobiologie, imunologie. Praha: ČSL JEP, 2019, roč. 68, č. 2, s. 59-64. ISSN 1210-7913.

@article{1551818,
   author = {Musil, Václav and Homola, Lukáš and Vrba, M. and Braunová, Adriana and Kravalová, Tamara and Malá, Miriam and Krbková, Lenka},
   article_location = {Praha},
   article_number = {2},
   keywords = {infants; neonates; Clostridium dlifklle; diarrhoea; paediatrics; colonisation},
   language = {eng},
   issn = {1210-7913},
   journal = {Čs. epidemiologie, mikrobiologie, imunologie},
   title = {Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study},
   url = {https://www.ncbi.nlm.nih.gov/pubmed/31398977},
   volume = {68},
   year = {2019}
}

TY  - JOUR
ID  - 1551818
AU  - Musil, Václav - Homola, Lukáš - Vrba, M. - Braunová, Adriana - Kravalová, Tamara - Malá, Miriam - Krbková, Lenka
PY  - 2019
TI  - Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study
JF  - Čs. epidemiologie, mikrobiologie, imunologie
VL  - 68
IS  - 2
SP  - 59-64
EP  - 59-64
PB  - ČSL JEP
SN  - 12107913
KW  - infants
KW  - neonates
KW  - Clostridium dlifklle
KW  - diarrhoea
KW  - paediatrics
KW  - colonisation
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31398977
L2  - https://www.ncbi.nlm.nih.gov/pubmed/31398977
N2  - Aims: Despite an increasing trend in Clostridium difficile infections (CDI) and high C difficile colonization rate especially among younger children. infants remain quite resistant to the disease. The goals of this study were to distinguish whether there exists a difference in CDI between children with or without diarrhoea, ascertain the prevalence of CDI, and assess CDI severity in children under 3 years with diarrhoea in our institution. Methods: A prospective study was conducted from May 2015 to June 2016. Children 3 years of age or younger were enrolled and into two groups. Every faecal sample was tested using a diagnostic two step screening algorithm including an immunochromatographic test and polymerase chain reaction. Results: The study enrolled 147 children with diarrhoea and 75 control patients. I he prevalence of CDI in children with diarrhoea was 2% (3/147), the prevalence of toxigenic C. difficile in the diarrhoeal group compared to the control group was 11.6 % (17/147) vs. 10.6% (8/75) (p < 0.9999). Conclusions: No significant difference was observed between infants with diarrhoea and the control group. We recommend not examining for C. difficile children not exhibiting specific risk factors.
ER  -

MUSIL, Václav, Lukáš HOMOLA, M. VRBA, Adriana BRAUNOVÁ, Tamara KRAVALOVÁ, Miriam MALÁ a Lenka KRBKOVÁ. Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study. \textit{Čs. epidemiologie, mikrobiologie, imunologie}. Praha: ČSL JEP, 2019, roč.~68, č.~2, s.~59-64. ISSN~1210-7913.

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