2019
Thermal efect of irreversible electroporation a high-frequency irreversible electroporation inside metallic stent ex vivo
JŮZA, Tomáš, Tomáš ROHAN, Peter MATKULČÍK, Dalibor ČERVINKA, Veronika NOVOTNÁ et. al.Základní údaje
Originální název
Thermal efect of irreversible electroporation a high-frequency irreversible electroporation inside metallic stent ex vivo
Autoři
JŮZA, Tomáš (203 Česká republika, garant, domácí), Tomáš ROHAN (203 Česká republika), Peter MATKULČÍK (703 Slovensko, domácí), Dalibor ČERVINKA (203 Česká republika), Veronika NOVOTNÁ (203 Česká republika), Vlastimil VÁLEK (203 Česká republika, domácí) a Tomáš ANDRAŠINA (703 Slovensko)
Vydání
CIRSE 2019, 2019
Další údaje
Jazyk
angličtina
Typ výsledku
Konferenční abstrakt
Obor
30224 Radiology, nuclear medicine and medical imaging
Stát vydavatele
Německo
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 2.034
Kód RIV
RIV/00216224:14110/19:00110837
Organizační jednotka
Lékařská fakulta
ISSN
Klíčová slova anglicky
irreversible electroporation; high-frequency irreversible electroporation; thermal effect; metal stent
Štítky
Příznaky
Mezinárodní význam
Změněno: 21. 4. 2020 11:16, Mgr. Tereza Miškechová
Anotace
V originále
Purpose: To compare electrical and thermal parameters of irreversible electroporation (IRE) and high-frequency irreversible electroporation (H-FIRE) using tubular electrode prototype in biliary metal stent. Material and methods: 3-electrode tubular catheter prototype was placed inside metallic biliary stent in ex vivo porcine liver model. 3 scenarios of stent occlusion using 2±1 mm thick piece of liver parenchyma were simulated. Only 2 electrodes were active in each time. IRE were performed by one hundred pulses at voltages 300V, 650V, 1000V and 1300V with 100 us pulse length. H-FIRE is a newer modifcation of electroporation methods using, in our case, 100 us burst of alternating polarity pulses of 2,5; 5; 10 and 25 us length, pause between pulses 0,5, 1 and 1,5 seconds with the same voltages as IRE. Values of electric current were measured. Thermal efects were monitored by infrared thermal imaging camera. Results: IRE and H-FIRE procedures were feasible in all settings with simulated obstruction of the voltages of 300 and 650V and in most of the cases with 1000 V. In higher voltages the safety limit of generator (12A) were exceeded. No signifcant diference in heating between IRE and H-FIRE was observed (p=0,49, Mann-Whitney). Maximal temperature increase in both methods was 7°C at 1000 V in model with one electrode in direct in contact with the stent and the other one with simulated obstruction. Conclusion: No signifcant diferences in thermal efects between IRE and H-FIRE delivering comparable amount of energy in metal stent were observed.
Návaznosti
| MUNI/A/0996/2018, interní kód MU |
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| MUNI/A/1574/2018, interní kód MU |
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