Looking at the health of past populations through the lens of
human dental calculus

a 2019

Looking at the health of past populations through the lens of human dental calculus

CHOCHOLOVÁ, Eva, Dana FIALOVÁ, Eva DROZDOVÁ, Radim SKOUPÝ, Kristýna BRZOBOHATÁ et. al.

Basic information

Original name

Looking at the health of past populations through the lens of human dental calculus

Authors

CHOCHOLOVÁ, Eva (203 Czech Republic, guarantor, belonging to the institution), Dana FIALOVÁ (203 Czech Republic, belonging to the institution), Eva DROZDOVÁ (203 Czech Republic, belonging to the institution), Radim SKOUPÝ (203 Czech Republic), Kristýna BRZOBOHATÁ (203 Czech Republic, belonging to the institution), Barbora ZWINSOVÁ (203 Czech Republic, belonging to the institution), Petra VÍDEŇSKÁ (203 Czech Republic, belonging to the institution) and Václav CHOCHOLA (203 Czech Republic, belonging to the institution)

Edition

The Biomania Student Scientific Meeting & EUSynBioS Symposium 2019, 2019

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

10608 Biochemistry and molecular biology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14310/19:00110957

Organization unit

Faculty of Science

ISBN

978-80-210-9373-7

Keywords (in Czech)

starobylá DNA; aDNA; patogen; zubní kámen; metagenomika

Keywords in English

ancient DNA; aDNA; pathogen; dental calculus; metagenomics

Abstract

V originále

Connection of ancient human dental calculus and molecular biology has so far brought up more questions than answers. Dental calculus is a calcified dental plaque and as such, it is mostly composed of bacteria and their products. This opens a door to the research of oral health as well as pathogens found in blood or respiratory system. The presented study shows the potential of molecular research of ancient human dental calculus in connection with health and the problems with authentication of acquired results. Several potential pathogens were detected by sequencing of 16S rDNA in Early Medieval specimens, but an even greater quantity of contaminating organisms was found. How does that change the usefulness of the applied approach? Is there a right way for the interpretation of metagenomic data derived from ancient samples?

Links

MUNI/C/1717/2016, interní kód MU

Name: Identifikace bakteriálně přenosných nemocí z historického zubního kamene

Investor: Masaryk University, Rector's Program

Citovat

CHOCHOLOVÁ, Eva, Dana FIALOVÁ, Eva DROZDOVÁ, Radim SKOUPÝ, Kristýna BRZOBOHATÁ, Barbora ZWINSOVÁ, Petra VÍDEŇSKÁ and Václav CHOCHOLA. Looking at the health of past populations through the lens of human dental calculus. In The Biomania Student Scientific Meeting & EUSynBioS Symposium 2019. 2019. ISBN 978-80-210-9373-7.

@proceedings{1569436,
   author = {Chocholová, Eva and Fialová, Dana and Drozdová, Eva and Skoupý, Radim and Brzobohatá, Kristýna and Zwinsová, Barbora and Vídeňská, Petra and Chochola, Václav},
   booktitle = {The Biomania Student Scientific Meeting & EUSynBioS Symposium 2019},
   keywords = {ancient DNA; aDNA; pathogen; dental calculus; metagenomics},
   language = {eng},
   isbn = {978-80-210-9373-7},
   title = {Looking at the health of past populations through the lens of human dental calculus},
   year = {2019}
}

TY  - CONF
ID  - 1569436
AU  - Chocholová, Eva - Fialová, Dana - Drozdová, Eva - Skoupý, Radim - Brzobohatá, Kristýna - Zwinsová, Barbora - Vídeňská, Petra - Chochola, Václav
PY  - 2019
TI  - Looking at the health of past populations through the lens of human dental calculus
SN  - 9788021093737
KW  - ancient DNA
KW  - aDNA
KW  - pathogen
KW  - dental calculus
KW  - metagenomics
N2  - Connection of ancient human dental calculus and molecular biology has so far brought up more questions than answers. Dental calculus is a calcified dental plaque and as such, it is mostly composed of bacteria and their products. This opens a door to the research of oral health as well as pathogens found in blood or respiratory system. The presented study shows the potential of molecular research of ancient human dental calculus in connection with health and the problems with authentication of acquired results. Several potential pathogens were detected by sequencing of 16S rDNA in Early Medieval specimens, but an even greater quantity of contaminating organisms was found. How does that change the usefulness of the applied approach? Is there a right way for the interpretation of metagenomic data derived from ancient samples?
ER  -

CHOCHOLOVÁ, Eva, Dana FIALOVÁ, Eva DROZDOVÁ, Radim SKOUPÝ, Kristýna BRZOBOHATÁ, Barbora ZWINSOVÁ, Petra VÍDEŇSKÁ and Václav CHOCHOLA. Looking at the health of past populations through the lens of human dental calculus. In \textit{The Biomania Student Scientific Meeting \&{} EUSynBioS Symposium 2019}. 2019. ISBN~978-80-210-9373-7.

Detailed Information on Publication Record