Sex differences in heart rate responses to postural
provocations

J 2019

Sex differences in heart rate responses to postural provocations

HNATKOVA, Katarina, Martina ŠIŠÁKOVÁ, Peter SMETANA, Ondřej TOMAN, Katharina M. HUSTER et. al.

Základní údaje

Originální název

Sex differences in heart rate responses to postural provocations

Autoři

HNATKOVA, Katarina (826 Velká Británie a Severní Irsko), Martina ŠIŠÁKOVÁ (203 Česká republika, domácí), Peter SMETANA (40 Rakousko), Ondřej TOMAN (203 Česká republika, domácí), Katharina M. HUSTER (276 Německo), Tomáš NOVOTNÝ (203 Česká republika, domácí), Georg SCHMIDT (276 Německo) a Marek MALIK (826 Velká Británie a Severní Irsko, garant)

Vydání

International Journal of Cardiology, Clare, Elsevier Ireland Ltd. 2019, 0167-5273

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.229

Kód RIV

RIV/00216224:14110/19:00112433

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.ijcard.2019.09.044

UT WoS

000502550800030

Klíčová slova anglicky

Sex differences; Postural changes; Heart rate; Heart rate variability; Autonomic modulations; Autonomic responsiveness; Responses to stress

Štítky

14110211, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 16. 1. 2020 08:06, Mgr. Tereza Miškechová

Anotace

V originále

Sex differences are known in several facets of cardiac electrophysiology, mostly concerning myocardial repolarisation. In this study, heart rate and heart rate variability (HRV) responses to postural provocations were compared in 175 and 176 healthy females and males, respectively (aged 33.1 +/- 9.1 years). Two different postural provocative tests with position changes supine -> sitting -> standing -> supine and supine -> standing -> sitting -> supine (15-min standing, 10-min other positions) were performed up to 4 times in each subject. Heart rate and heart rate variability spectral indices were measured in 5-min windows before positional changes. At supine position, females had averaged heart rate approximately 5 beats per minute (bpm) faster than males and this sex difference was practically constant during the postural changes. In both sexes, change supine -> sitting and supine -> standing increased heart rate by approximately 10 and 30 bpm, respectively, with no statistical differences between the sex groups. At supine baseline, females had normalised high frequency components (nHF) of HRV approximately 7% larger compared to males (p < 0.001). While the same difference in nHF was found at sitting, the change to standing position lead to significantly larger nHF reduction in females compared to males (mean changes 22.5 vs 17.2%, p < 0.001). This shows that despite similar heart rate increase, females respond to standing by more substantial shifts in cardiac sympatho- vagal modulations. This makes it plausible to speculate that the differences in autonomic reactions to stress contribute to the known sex-differences in psychosocial responses to stressful situations and to the known difference in susceptibility to ventricular fibrillation between females and males. (C) 2019 The Authors. Published by Elsevier B.V.

Citovat

HNATKOVA, Katarina, Martina ŠIŠÁKOVÁ, Peter SMETANA, Ondřej TOMAN, Katharina M. HUSTER, Tomáš NOVOTNÝ, Georg SCHMIDT a Marek MALIK. Sex differences in heart rate responses to postural provocations. International Journal of Cardiology. Clare: Elsevier Ireland Ltd., 2019, roč. 297, DEC 15 2019, s. 126-134. ISSN 0167-5273. Dostupné z: https://dx.doi.org/10.1016/j.ijcard.2019.09.044.

@article{1604800,
   author = {Hnatkova, Katarina and Šišáková, Martina and Smetana, Peter and Toman, Ondřej and Huster, Katharina M. and Novotný, Tomáš and Schmidt, Georg and Malik, Marek},
   article_location = {Clare},
   article_number = {DEC 15 2019},
   doi = {http://dx.doi.org/10.1016/j.ijcard.2019.09.044},
   keywords = {Sex differences; Postural changes; Heart rate; Heart rate variability; Autonomic modulations; Autonomic responsiveness; Responses to stress},
   language = {eng},
   issn = {0167-5273},
   journal = {International Journal of Cardiology},
   title = {Sex differences in heart rate responses to postural provocations},
   url = {http://dx.doi.org/10.1016/j.ijcard.2019.09.044},
   volume = {297},
   year = {2019}
}

TY  - JOUR
ID  - 1604800
AU  - Hnatkova, Katarina - Šišáková, Martina - Smetana, Peter - Toman, Ondřej - Huster, Katharina M. - Novotný, Tomáš - Schmidt, Georg - Malik, Marek
PY  - 2019
TI  - Sex differences in heart rate responses to postural provocations
JF  - International Journal of Cardiology
VL  - 297
IS  - DEC 15 2019
SP  - 126-134
EP  - 126-134
PB  - Elsevier Ireland Ltd.
SN  - 01675273
KW  - Sex differences
KW  - Postural changes
KW  - Heart rate
KW  - Heart rate variability
KW  - Autonomic modulations
KW  - Autonomic responsiveness
KW  - Responses to stress
UR  - http://dx.doi.org/10.1016/j.ijcard.2019.09.044
L2  - http://dx.doi.org/10.1016/j.ijcard.2019.09.044
N2  - Sex differences are known in several facets of cardiac electrophysiology, mostly concerning myocardial repolarisation. In this study, heart rate and heart rate variability (HRV) responses to postural provocations were compared in 175 and 176 healthy females and males, respectively (aged 33.1 +/- 9.1 years). Two different postural provocative tests with position changes supine -> sitting -> standing -> supine and supine -> standing -> sitting -> supine (15-min standing, 10-min other positions) were performed up to 4 times in each subject. Heart rate and heart rate variability spectral indices were measured in 5-min windows before positional changes. At supine position, females had averaged heart rate approximately 5 beats per minute (bpm) faster than males and this sex difference was practically constant during the postural changes. In both sexes, change supine -> sitting and supine -> standing increased heart rate by approximately 10 and 30 bpm, respectively, with no statistical differences between the sex groups. At supine baseline, females had normalised high frequency components (nHF) of HRV approximately 7% larger compared to males (p < 0.001). While the same difference in nHF was found at sitting, the change to standing position lead to significantly larger nHF reduction in females compared to males (mean changes 22.5 vs 17.2%, p < 0.001). This shows that despite similar heart rate increase, females respond to standing by more substantial shifts in cardiac sympatho- vagal modulations. This makes it plausible to speculate that the differences in autonomic reactions to stress contribute to the known sex-differences in psychosocial responses to stressful situations and to the known difference in susceptibility to ventricular fibrillation between females and males. (C) 2019 The Authors. Published by Elsevier B.V.
ER  -

HNATKOVA, Katarina, Martina ŠIŠÁKOVÁ, Peter SMETANA, Ondřej TOMAN, Katharina M. HUSTER, Tomáš NOVOTNÝ, Georg SCHMIDT a Marek MALIK. Sex differences in heart rate responses to postural provocations. \textit{International Journal of Cardiology}. Clare: Elsevier Ireland Ltd., 2019, roč.~297, DEC 15 2019, s.~126-134. ISSN~0167-5273. Dostupné z: https://dx.doi.org/10.1016/j.ijcard.2019.09.044.

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