An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice
EYER, Luděk; Antoine NOUGAIRÈDE; Marie UHLÍŘOVÁ; Jean-Sélim DRIOUICH; Darina ZOUHAROVÁ et al.
An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice
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EYER, Luděk; Antoine NOUGAIRÈDE; Marie UHLÍŘOVÁ; Jean-Sélim DRIOUICH; Darina ZOUHAROVÁ; James J. VALDÉS; Jan HAVIERNIK; Ernest A. GOULD; Erik DE CLERCQ; Xavier DE LAMBALLERIE a Daniel RŮŽEK
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JOURNAL OF VIROLOGY, WASHINGTON, AMER SOC MICROBIOLOGY, 2019, 0022-538X
EYER, Luděk; Antoine NOUGAIRÈDE; Marie UHLÍŘOVÁ; Jean-Sélim DRIOUICH; Darina ZOUHAROVÁ; James J. VALDÉS; Jan HAVIERNIK; Ernest A. GOULD; Erik DE CLERCQ; Xavier DE LAMBALLERIE a Daniel RŮŽEK. An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice. JOURNAL OF VIROLOGY. WASHINGTON: AMER SOC MICROBIOLOGY, 2019. ISSN 0022-538X. Dostupné z: https://doi.org/10.1128/JVI.00367-19.
@article{1614056, author = {Eyer, Luděk and Nougairède, Antoine and Uhlířová, Marie and Driouich, JeanandSélim and Zouharová, Darina and Valdés, James J. and Haviernik, Jan and Gould, Ernest A. and De Clercq, Erik and de Lamballerie, Xavier and Růžek, Daniel}, article_location = {WASHINGTON}, doi = {https://doi.org/10.1128/JVI.00367-19}, keywords = {BCX4430; attenuation; drug resistance; galidesivir; mutation; tick-borne encephalitis virus}, issn = {0022-538X}, journal = {JOURNAL OF VIROLOGY}, title = {An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice}, url = {https://jvi.asm.org/content/93/16/e00367-19.long}, year = {2019} }
TY - JOUR ID - 1614056 AU - Eyer, Luděk - Nougairède, Antoine - Uhlířová, Marie - Driouich, Jean-Sélim - Zouharová, Darina - Valdés, James J. - Haviernik, Jan - Gould, Ernest A. - De Clercq, Erik - de Lamballerie, Xavier - Růžek, Daniel PY - 2019 TI - An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice JF - JOURNAL OF VIROLOGY PB - AMER SOC MICROBIOLOGY SN - 0022538X KW - BCX4430 KW - attenuation KW - drug resistance KW - galidesivir KW - mutation KW - tick-borne encephalitis virus UR - https://jvi.asm.org/content/93/16/e00367-19.long ER -
EYER, Luděk; Antoine NOUGAIRÈDE; Marie UHLÍŘOVÁ; Jean-Sélim DRIOUICH; Darina ZOUHAROVÁ; James J. VALDÉS; Jan HAVIERNIK; Ernest A. GOULD; Erik DE CLERCQ; Xavier DE LAMBALLERIE a Daniel RŮŽEK. An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice. \textit{JOURNAL OF VIROLOGY}. WASHINGTON: AMER SOC MICROBIOLOGY, 2019. ISSN~0022-538X. Dostupné z: https://doi.org/10.1128/JVI.00367-19.