D 2018

THE BIOCHEMICAL PROCESS OF LUBRICANT FILM FORMATION IN JOINT REPLACEMENT

RUFAQUA, R., M. VRBKA, D. CHOUDHURY, Dušan HEMZAL, I. KRUPKA et. al.

Základní údaje

Originální název

THE BIOCHEMICAL PROCESS OF LUBRICANT FILM FORMATION IN JOINT REPLACEMENT

Autoři

RUFAQUA, R., M. VRBKA, D. CHOUDHURY, Dušan HEMZAL (203 Česká republika, garant, domácí), I. KRUPKA a M. HARTL

Vydání

PRAGUE 9, ENGINEERING MECHANICS 2018 PROCEEDINGS, VOL 24, od s. 725-728, 4 s. 2018

Nakladatel

ACAD SCI CZECH REPUBLIC, INST THEORETICAL & APPLIED MECHANICS

Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Obor

20301 Mechanical engineering

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

tištěná verze "print"

Odkazy

Kód RIV

RIV/00216224:14310/18:00113181

Organizační jednotka

Přírodovědecká fakulta

ISBN

978-80-86246-88-8

ISSN

UT WoS

000465489800181

Klíčová slova anglicky

synovial fluid; film formation; Raman spectroscopy; bio-tribology; tribo-chemistry

Štítky

Příznaky

Recenzováno
Změněno: 19. 4. 2020 11:58, Mgr. Marie Šípková, DiS.

Anotace

V originále

The main objective of this study is to clarify the biochemical reactions of the formation of the lubricating film between the head and the cup of the joint replacement. The chemical changes taking place within the proteins of synovial fluid constitute after joint replacements need to be observed. Film formation is also dependent on the pH of the solution and static and rolling conditions, viscosity, concentration of the solution and other mechanical properties of the total environmental condition of joint replacement. The chemical composition of synovial fluid is predominantly considered to explain the development of film on the ball. The experiment was conducted in ball-on-cup configuration in a hip joint simulator, where the ball was made of cobalt chromium molybdenum alloy and the cup was of optical glass. The used proteins albumin, gamma-globulin and bovine serum were the reactants of this process. To analyze the products of the reaction, Raman spectroscopic method was used to observe the changes among proteins. After the analysis of the Raman spectra, it is assumed heterogeneous catalysis process could be taken place on the metal ball during chemical reaction. The results could have significant information regarding lubricating film development within the joint replacement.

Návaznosti

LQ1601, projekt VaV
Název: CEITEC 2020 (Akronym: CEITEC2020)
Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, CEITEC 2020