BOČKOVÁ, Martina a Ivan REKTOR. Impairment of brain functions in Parkinson's disease reflected by alterations in neural connectivity in EEG studies: A viewpoint. Clinical Neurophysiology. Clare: Elsevier Ireland, 2019, roč. 130, č. 2, s. 239-247. ISSN 1388-2457. Dostupné z: https://dx.doi.org/10.1016/j.clinph.2018.11.013.
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Základní údaje
Originální název Impairment of brain functions in Parkinson's disease reflected by alterations in neural connectivity in EEG studies: A viewpoint
Autoři BOČKOVÁ, Martina (203 Česká republika, domácí) a Ivan REKTOR (203 Česká republika, garant, domácí).
Vydání Clinical Neurophysiology, Clare, Elsevier Ireland, 2019, 1388-2457.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30210 Clinical neurology
Stát vydavatele Irsko
Utajení není předmětem státního či obchodního tajemství
WWW URL
Impakt faktor Impact factor: 3.214
Kód RIV RIV/00216224:14740/19:00108608
Organizační jednotka Středoevropský technologický institut
Doi http://dx.doi.org/10.1016/j.clinph.2018.11.013
UT WoS 000456164600006
Klíčová slova anglicky Parkinson's disease; EEG; Local field potentials; Functional connectivity; Graph theory; Deep brain stimulation
Štítky rivok
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: Mgr. Pavla Foltynová, Ph.D., učo 106624. Změněno: 12. 5. 2020 13:35.
Anotace
Clinical symptoms of Parkinson's disease (PD) are accompanied by pathological phenomena detected locally in the basal ganglia (BG) as changes in local field potentials (LFPs) and also in cortical regions by electroencephalography (EEG). The literature published mainly between 2000 and 2017 was reviewed with an emphasis on approaches emerging after 2000, in particular on oscillatory dynamics, connectivity studies, and deep brain stimulation. Eighty-five articles were reviewed. The main observations were a general slowing of background activity, excessive synchronization of beta activity, and disturbed movement-related gamma oscillations in the BG and in the cortico-subcortical and cortico-cortical motor loops, suppressible by dopaminergic medication as well as by high-frequency deep brain stimulation (DBS). Non-motor symptoms are related mainly to changes in the alpha frequency range. EEG parameters can be useful in defining the risk of dementia in PD. Further progress was reported recently using advanced analytical technologies and high-performance computing (graph theory). Detailed knowledge of LFPs in PD enabled progress particularly in DBS therapy, which requires optimizing the clinical effect and minimizing adverse side effects. The neurocognitive networks and their dysfunction in PD and DBS therapy are promising targets for future research. (C) 2018 International Federation of Clinical Neurophysiology. Published by Elsevier B.V.
Návaznosti
NV16-33798A, projekt VaVNázev: Modulace funkční konektivity kortikálních sítí vlivem STN DBS
VytisknoutZobrazeno: 19. 5. 2024 22:46