J 2020

Poor ventilatory efficiency during exercise may predict prolonged air leak after pulmonary lobectomy

BRAT, Kristián, Miloš CHOBOLA, Pavel HOMOLKA, Michaela HEROUTOVÁ, Michal BENEJ et. al.

Základní údaje

Originální název

Poor ventilatory efficiency during exercise may predict prolonged air leak after pulmonary lobectomy

Autoři

BRAT, Kristián (703 Slovensko, domácí), Miloš CHOBOLA (203 Česká republika, domácí), Pavel HOMOLKA (203 Česká republika, domácí), Michaela HEROUTOVÁ (203 Česká republika), Michal BENEJ (703 Slovensko, domácí), Ladislav MITÁŠ (203 Česká republika, domácí), Lyle J. OLSON (840 Spojené státy) a Ivan ČUNDRLE (203 Česká republika, domácí)

Vydání

Interactive CardioVascular and Thoracic Surgery, OXFORD, OXFORD UNIV PRESS, 2020, 1569-9293

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30203 Respiratory systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 1.905

Kód RIV

RIV/00216224:14110/20:00115432

Organizační jednotka

Lékařská fakulta

DOI

UT WoS

000517789800011

Klíčová slova anglicky

V-E/VCO2 slope; Prolonged air leak; Postoperative complications; Anatomical lung resection

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 20. 3. 2020 10:14, Mgr. Tereza Miškechová

Anotace

V originále

Poor ventilatory efficiency, defined as the increase in minute ventilation relative to carbon dioxide production during exercise (V-E/VCO2 slope), may be associated with dynamic hyperinflation and thereby promote the development of prolonged air leak (PAL) after lung resection. Consecutive lung lobectomy candidates (n = 96) were recruited for this prospective two-centre study. All subjects underwent pulmonary function tests and cardiopulmonary exercise testing prior to surgery. PAL was defined as the presence of air leaks from the chest tube on the 5th postoperative day and developed in 28 (29%) subjects. Subjects with PAL were not different in terms of age, sex, American Society of Anesthesiologists class, type of surgery (thoracotomy/video-assisted thoracoscopic surgery) and site of surgery (right/left lung; upper/lower lobes). Subjects with PAL had more frequent pleural adhesions (50% vs 21%; P = 0.006) and steeper V-E/VCO2 slope (35 +/- 7 vs 30 +/- 5; P = 0.001). Stepwise logistic regression showed that only the presence of pleural adhesions [odds ratio (OR) 3.9, 95% confidence interval (CI) 1.4-10.9; P = 0.008] and V-E/VCO2 slope (OR 1.1, 95% CI 1.0-1.2; P = 0.003) were independently associated with PAL (AUC 0.74, 95% CI 0.62-0.86). We conclude that a high V-E/VCO2 slope during exercise may be helpful in identifying patients at greater risk for the development of PAL after lung lobectomy.