| NOVÁK, Jan, Táňa MACHÁČKOVÁ, Tereza NOVÁKOVÁ, Július GODAVA, Petr HUDE, Víta ŽAMPACHOVÁ, Jan OPPELT, Petr NĚMEC, Helena BEDÁŇOVÁ, Ondřej SLABÝ, Julie DOBROVOLNÁ, Jan KREJČÍ a Lenka ŠPINAROVÁ. Identifying urinary microRNAs for heart allograft rejection monitoring using small RNA sequencing - Pilot results. In ESC365. 2019. ISSN 1388-9842. |
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@proceedings{1641757,
author = {Novák, Jan and Macháčková, Táňa and Nováková, Tereza and Godava, Július and Hude, Petr and Žampachová, Víta and Oppelt, Jan and Němec, Petr and Bedáňová, Helena and Slabý, Ondřej and Dobrovolná, Julie and Krejčí, Jan and Špinarová, Lenka},
booktitle = {ESC365},
keywords = {urinary microRNAs},
language = {eng},
title = {Identifying urinary microRNAs for heart allograft rejection monitoring using small RNA sequencing - Pilot results},
year = {2019}
}
TY - CONF
ID - 1641757
AU - Novák, Jan - Macháčková, Táňa - Nováková, Tereza - Godava, Július - Hude, Petr - Žampachová, Víta - Oppelt, Jan - Němec, Petr - Bedáňová, Helena - Slabý, Ondřej - Dobrovolná, Julie - Krejčí, Jan - Špinarová, Lenka
PY - 2019
TI - Identifying urinary microRNAs for heart allograft rejection monitoring using small RNA sequencing - Pilot results
KW - urinary microRNAs
N2 - Heart failure (HF) represents one of the leading causes of death in the developed countries and heart transplantation (HT) is the only solution for patients with terminal refractory HF. Patients after HT are at risk of acute cellular rejection (ACR) potentially causing graft damage and failure. Diagnostics of ACR is based on histopathologic evaluation of endomyocardial biopsies (EMB) as no non-invasive biomarker has been found yet. microRNAs (miRNAs, miRs) are tiny non-coding RNA molecules involved in post-transcriptional regulation of gene expression. Extracellularly they are potentially involved in intercellular communication and because of their high stability they represent novel potential biomarkers.
ER -
NOVÁK, Jan, Táňa MACHÁČKOVÁ, Tereza NOVÁKOVÁ, Július GODAVA, Petr HUDE, Víta ŽAMPACHOVÁ, Jan OPPELT, Petr NĚMEC, Helena BEDÁŇOVÁ, Ondřej SLABÝ, Julie DOBROVOLNÁ, Jan KREJČÍ a Lenka ŠPINAROVÁ. Identifying urinary microRNAs for heart allograft rejection monitoring using small RNA sequencing - Pilot results. In \textit{ESC365}. 2019. ISSN~1388-9842.
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