Risk assessment of EDCs in Europe based on human biomonitoring
data

a 2019

Risk assessment of EDCs in Europe based on human biomonitoring data

SARIGIANNIS, D.; S. KARAKITSIOS; A. GOTTI; V. KUMAR; M. SCHUHMACHER et al.

Základní údaje

Originální název

Risk assessment of EDCs in Europe based on human biomonitoring data

Autoři

SARIGIANNIS, D.; S. KARAKITSIOS; A. GOTTI; V. KUMAR; M. SCHUHMACHER; C. BROCHOT; A. CREPET; Martin SCHERINGER; Elena DOMINGUEZ ROMERO; J. BESSEMS; K. BAKEN; M. HORVAT a J. TRATNIK

Vydání

55th Congress of the European-Societies-of-Toxicology (EUROTOX) - Toxicology - Science Providing Solutions, 2019

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30108 Toxicology

Stát vydavatele

Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.569

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/19:00113702

Organizační jednotka

Přírodovědecká fakulta

ISSN

UT WoS

000484771800797

Klíčová slova anglicky

human biomonitoring

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 20. 4. 2020 20:55, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

A major advantage of human biomonitoring (HBM) data is that they provide an integrated overview of the body burden to xenobiotics that an individual is exposed to. However, quantification of exposure based on HBM data poses significant challenges that are worth facing, given the opportunities that HBM provides in terms of informing and effectively supporting risk assessment. Based on the above, the aim of this within the HBM4EU project was to derive EU-wide external exposure estimates starting from HBM data and to derive and risk characterization ratio (RCR) by comparing these estimates with existing regulatory thresholds. For the reconstruction of exposure the INTEGRA computational platform was properly parameterised for the compounds of interest, namely bisphenol-A (BPA), phthalates (DEHP, DiNP and DnBP) and DINCH, emerging flame retardants (TCEP) and Perfluorinated compounds (PFOA and PFOS).

Citovat

SARIGIANNIS, D.; S. KARAKITSIOS; A. GOTTI; V. KUMAR; M. SCHUHMACHER; C. BROCHOT; A. CREPET; Martin SCHERINGER; Elena DOMINGUEZ ROMERO; J. BESSEMS; K. BAKEN; M. HORVAT a J. TRATNIK. Risk assessment of EDCs in Europe based on human biomonitoring data. In 55th Congress of the European-Societies-of-Toxicology (EUROTOX) - Toxicology - Science Providing Solutions. 2019. ISSN 0378-4274.

@proceedings{1647716,
   author = {Sarigiannis, D. and Karakitsios, S. and Gotti, A. and Kumar, V. and Schuhmacher, M. and Brochot, C. and Crepet, A. and Scheringer, Martin and Dominguez Romero, Elena and Bessems, J. and Baken, K. and Horvat, M. and Tratnik, J.},
   booktitle = {55th Congress of the European-Societies-of-Toxicology (EUROTOX) - Toxicology - Science Providing Solutions},
   keywords = {human biomonitoring},
   language = {eng},
   title = {Risk assessment of EDCs in Europe based on human biomonitoring data},
   url = {https://www.sciencedirect.com/science/article/pii/S0378427419302486},
   year = {2019}
}

TY  - CONF
ID  - 1647716
AU  - Sarigiannis, D. - Karakitsios, S. - Gotti, A. - Kumar, V. - Schuhmacher, M. - Brochot, C. - Crepet, A. - Scheringer, Martin - Dominguez Romero, Elena - Bessems, J. - Baken, K. - Horvat, M. - Tratnik, J.
PY  - 2019
TI  - Risk assessment of EDCs in Europe based on human biomonitoring data
KW  - human biomonitoring
UR  - https://www.sciencedirect.com/science/article/pii/S0378427419302486
L2  - https://www.sciencedirect.com/science/article/pii/S0378427419302486
N2  - A major advantage of human biomonitoring (HBM) data is that they provide an integrated overview of the body burden to xenobiotics that an individual is exposed to. However, quantification of exposure based on HBM data poses significant challenges that are worth facing, given the opportunities that HBM provides in terms of informing and effectively supporting risk assessment. Based on the above, the aim of this within the HBM4EU project was to derive EU-wide external exposure estimates starting from HBM data and to derive and risk characterization ratio (RCR) by comparing these estimates with existing regulatory thresholds. For the reconstruction of exposure the INTEGRA computational platform was properly parameterised for the compounds of interest, namely bisphenol-A (BPA), phthalates (DEHP, DiNP and DnBP) and DINCH, emerging flame retardants (TCEP) and Perfluorinated compounds (PFOA and PFOS).
ER  -

SARIGIANNIS, D.; S. KARAKITSIOS; A. GOTTI; V. KUMAR; M. SCHUHMACHER; C. BROCHOT; A. CREPET; Martin SCHERINGER; Elena DOMINGUEZ ROMERO; J. BESSEMS; K. BAKEN; M. HORVAT a J. TRATNIK. Risk assessment of EDCs in Europe based on human biomonitoring data. In \textit{55th Congress of the European-Societies-of-Toxicology (EUROTOX) - Toxicology - Science Providing Solutions}. 2019. ISSN~0378-4274.

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