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@article{1652420,
author = {Jabandžiev, Petr and Pinkasová, Tereza and Kunovský, Lumír and Papež, Jan and Jouza, Martin and Karlínová, Bára and Nováčková, Martina and Urík, Milan and Aulická, Štefánia and Slabý, Ondřej and Bohošová, Júlia and Bajerová, Kateřina and Bajer, Milan and Goel, Ajay},
article_location = {Philadelphia},
article_number = {5},
doi = {http://dx.doi.org/10.1097/MPG.0000000000002660},
keywords = {children; Crohn disease; Czech Republic; incidence; inflammatory bowel disease; ulcerative colitis},
language = {eng},
issn = {0277-2116},
journal = {Journal of Pediatric Gastroenterology and Nutrition},
title = {Regional Incidence of Inflammatory Bowel Disease in a Czech Pediatric Population: 16 Years of Experience (2002–2017)},
url = {https://journals.lww.com/jpgn/FullText/2020/05000/Regional_Incidence_of_Inflammatory_Bowel_Disease.12.aspx},
volume = {70},
year = {2020}
}
TY - JOUR
ID - 1652420
AU - Jabandžiev, Petr - Pinkasová, Tereza - Kunovský, Lumír - Papež, Jan - Jouza, Martin - Karlínová, Bára - Nováčková, Martina - Urík, Milan - Aulická, Štefánia - Slabý, Ondřej - Bohošová, Júlia - Bajerová, Kateřina - Bajer, Milan - Goel, Ajay
PY - 2020
TI - Regional Incidence of Inflammatory Bowel Disease in a Czech Pediatric Population: 16 Years of Experience (2002–2017)
JF - Journal of Pediatric Gastroenterology and Nutrition
VL - 70
IS - 5
SP - 586-592
EP - 586-592
PB - LIPPINCOTT WILLIAMS & WILKINS
SN - 02772116
KW - children
KW - Crohn disease
KW - Czech Republic
KW - incidence
KW - inflammatory bowel disease
KW - ulcerative colitis
UR - https://journals.lww.com/jpgn/FullText/2020/05000/Regional_Incidence_of_Inflammatory_Bowel_Disease.12.aspx
L2 - https://journals.lww.com/jpgn/FullText/2020/05000/Regional_Incidence_of_Inflammatory_Bowel_Disease.12.aspx
N2 - Objectives: Inflammatory bowel disease (IBD) is today a global disease, the incidence of which is growing in the pediatric population. This prospective study aims to decipher IBD incidence and its trend in a pediatric population through 16 years in the South Moravian Region of the Czech Republic. Methods: We evaluated data concerning 358 pediatric patients with newly diagnosed IBD at University Hospital Brno, which is a gastroenterology center for the entire pediatric population (0-18 years) and cares for all pediatric IBD patients in the South Moravian Region (1,187,667 inhabitants). Results: The study encompassed 3,488,907 children during 16 years. We diagnosed 192 children (53.6%) with Crohn disease (CD), 123 (34.4%) with ulcerative colitis (UC), and 43 (12.0%) with IBD-unclassified (IBD-U). The incidence of IBD increased from 3.8 (CD 2.9, UC 0.9, and IBD-U 0.0) per 100 000/year in 2002 to 14.7 (CD 9.8, UC 4.0, and IBD-U 0.9) per 100,000/year in 2017 (P < 0.001). The overall IBD incidence per 100,000/year was 9.8 (95% confidence interval [CI]: 8.8--10.9). Constituent incidences per 100,000/year were CD 5.2 (95% CI: 4.5--6.0), UC 3.4 (95% CI: 2.8--4.0), and IBD-U 1.2 (95% CI: 0.9--1.6). IBD incidence was projected to reach 18.9 per 100,000/year in 2022. Conclusions: The overall incidence of pediatric IBD in the Czech Republic is increasing, and especially that of CD, whereas trends in UC and IBD-U appear to be constant. These data highlight the need to identify risk factors involved in the rising incidence of IBD.
ER -
JABANDŽIEV, Petr, Tereza PINKASOVÁ, Lumír KUNOVSKÝ, Jan PAPEŽ, Martin JOUZA, Bára KARLÍNOVÁ, Martina NOVÁČKOVÁ, Milan URÍK, Štefánia AULICKÁ, Ondřej SLABÝ, Júlia BOHOŠOVÁ, Kateřina BAJEROVÁ, Milan BAJER and Ajay GOEL. Regional Incidence of Inflammatory Bowel Disease in a Czech Pediatric Population: 16 Years of Experience (2002–2017). \textit{Journal of Pediatric Gastroenterology and Nutrition}. Philadelphia: LIPPINCOTT WILLIAMS \&{} WILKINS, 2020, vol.~70, No~5, p.~586-592. ISSN~0277-2116. Available from: https://dx.doi.org/10.1097/MPG.0000000000002660.
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