2020
Executable Biochemical Space for Specification and Analysis of Biochemical Systems
TROJÁK, Matej, David ŠAFRÁNEK, Lukrécia MERTOVÁ a Luboš BRIMZákladní údaje
Originální název
Executable Biochemical Space for Specification and Analysis of Biochemical Systems
Autoři
Vydání
7th Workshop on Hybrid Systems and Biology, 2020
Další údaje
Jazyk
angličtina
Typ výsledku
Prezentace na konferencích
Obor
10201 Computer sciences, information science, bioinformatics
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Organizační jednotka
Fakulta informatiky
Klíčová slova anglicky
systems biology; rule-based modelling; annotation
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 15. 4. 2021 11:40, doc. RNDr. David Šafránek, Ph.D.
Anotace
V originále
We present a rule-based language called Biochemical Space Language (BCSL) as an integral part of a general framework called Comprehensive Modelling Platform, developed for comprehensive modelling in systems biology. The general goal of the platform is to respect the need for maintaining existing ODE models but allows to align them with a mechanistic rule-based description that is understandable by biologists, compact in size, executable in terms of allowing basic analysis tasks ensuring consistency of the description, and provides links to existing bioinformatics annotation databases. Such a comprehensive solution allows to support effort of modellers in building mathematical models that have clear biochemical meaning and can be easily integrated. Moreover, mechanistic descriptions can be later used as computational models having all advantages of rule-based modelling.
Návaznosti
| GA15-11089S, projekt VaV |
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| MUNI/A/1050/2019, interní kód MU |
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