The role of plant-derived natural substances as
immunomodulatory agents in carcinogenesis

J 2020

The role of plant-derived natural substances as immunomodulatory agents in carcinogenesis

SAMEC, Marek, Alena LISKOVA, Lenka KOKLESOVA, Samson Mathews SAMUEL, Radovan MURIN et. al.

Základní údaje

Originální název

The role of plant-derived natural substances as immunomodulatory agents in carcinogenesis

Autoři

SAMEC, Marek (703 Slovensko), Alena LISKOVA (703 Slovensko), Lenka KOKLESOVA (703 Slovensko), Samson Mathews SAMUEL (356 Indie), Radovan MURIN (703 Slovensko), Pavol ZUBOR (703 Slovensko), Jan BUJNAK (703 Slovensko), Taeg Kyu KWON (410 Korejská republika), Dietrich BUSSELBERG (276 Německo), Robert PROSECKÝ (203 Česká republika, domácí), Martin CAPRNDA (703 Slovensko), Luis RODRIGO (724 Španělsko), Rachele CICCOCIOPPO (380 Itálie), Peter KRUŽLIAK (703 Slovensko, garant, domácí) a Peter KUBATKA (703 Slovensko)

Vydání

Journal of cancer research and clinical oncology, Germany, Springer-Verlag, 2020, 0171-5216

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30204 Oncology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.553

Kód RIV

RIV/00216224:14110/20:00116763

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1007/s00432-020-03424-2

UT WoS

000577893800001

Klíčová slova anglicky

Cancer; Immunomodulation; Cytokines; Phytochemicals; Preclinical and clinical research

Štítky

14110116, 14110121, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 12. 5. 2021 14:05, Mgr. Tereza Miškechová

Anotace

V originále

The role of immune system in carcinogenesis represents fundamental events associated with cancer eradication; however, tumor evolution is connected with various mechanisms of tumor evasion and progression of cancer. Based on recent evidence, phytochemicals are directly associated with immunomodulation of the innate and adaptive immunity via different mechanisms of action including stimulation and amplification of immune cells, humoral compartments, and associated molecules. This comprehensive study focuses on immunomodulating potential of phytochemicals (mixture in plants or separately such as individual phytochemical) and their impact on regulation of immune response during cancer development, immune tolerance, and immune escape. Clinical application of phytochemicals as modulators of host immunity against cancer may represent perspective approach in anticancer therapy.

Citovat

SAMEC, Marek, Alena LISKOVA, Lenka KOKLESOVA, Samson Mathews SAMUEL, Radovan MURIN, Pavol ZUBOR, Jan BUJNAK, Taeg Kyu KWON, Dietrich BUSSELBERG, Robert PROSECKÝ, Martin CAPRNDA, Luis RODRIGO, Rachele CICCOCIOPPO, Peter KRUŽLIAK a Peter KUBATKA. The role of plant-derived natural substances as immunomodulatory agents in carcinogenesis. Journal of cancer research and clinical oncology. Germany: Springer-Verlag, 2020, roč. 146, č. 12, s. 3137-3154. ISSN 0171-5216. Dostupné z: https://dx.doi.org/10.1007/s00432-020-03424-2.

@article{1687754,
   author = {Samec, Marek and Liskova, Alena and Koklesova, Lenka and Samuel, Samson Mathews and Murin, Radovan and Zubor, Pavol and Bujnak, Jan and Kwon, Taeg Kyu and Busselberg, Dietrich and Prosecký, Robert and Caprnda, Martin and Rodrigo, Luis and Ciccocioppo, Rachele and Kružliak, Peter and Kubatka, Peter},
   article_location = {Germany},
   article_number = {12},
   doi = {http://dx.doi.org/10.1007/s00432-020-03424-2},
   keywords = {Cancer; Immunomodulation; Cytokines; Phytochemicals; Preclinical and clinical research},
   language = {eng},
   issn = {0171-5216},
   journal = {Journal of cancer research and clinical oncology},
   title = {The role of plant-derived natural substances as immunomodulatory agents in carcinogenesis},
   url = {https://link.springer.com/article/10.1007%2Fs00432-020-03424-2},
   volume = {146},
   year = {2020}
}

TY  - JOUR
ID  - 1687754
AU  - Samec, Marek - Liskova, Alena - Koklesova, Lenka - Samuel, Samson Mathews - Murin, Radovan - Zubor, Pavol - Bujnak, Jan - Kwon, Taeg Kyu - Busselberg, Dietrich - Prosecký, Robert - Caprnda, Martin - Rodrigo, Luis - Ciccocioppo, Rachele - Kružliak, Peter - Kubatka, Peter
PY  - 2020
TI  - The role of plant-derived natural substances as immunomodulatory agents in carcinogenesis
JF  - Journal of cancer research and clinical oncology
VL  - 146
IS  - 12
SP  - 3137-3154
EP  - 3137-3154
PB  - Springer-Verlag
SN  - 01715216
KW  - Cancer
KW  - Immunomodulation
KW  - Cytokines
KW  - Phytochemicals
KW  - Preclinical and clinical research
UR  - https://link.springer.com/article/10.1007%2Fs00432-020-03424-2
L2  - https://link.springer.com/article/10.1007%2Fs00432-020-03424-2
N2  - The role of immune system in carcinogenesis represents fundamental events associated with cancer eradication; however, tumor evolution is connected with various mechanisms of tumor evasion and progression of cancer. Based on recent evidence, phytochemicals are directly associated with immunomodulation of the innate and adaptive immunity via different mechanisms of action including stimulation and amplification of immune cells, humoral compartments, and associated molecules. This comprehensive study focuses on immunomodulating potential of phytochemicals (mixture in plants or separately such as individual phytochemical) and their impact on regulation of immune response during cancer development, immune tolerance, and immune escape. Clinical application of phytochemicals as modulators of host immunity against cancer may represent perspective approach in anticancer therapy.
ER  -

SAMEC, Marek, Alena LISKOVA, Lenka KOKLESOVA, Samson Mathews SAMUEL, Radovan MURIN, Pavol ZUBOR, Jan BUJNAK, Taeg Kyu KWON, Dietrich BUSSELBERG, Robert PROSECKÝ, Martin CAPRNDA, Luis RODRIGO, Rachele CICCOCIOPPO, Peter KRUŽLIAK a Peter KUBATKA. The role of plant-derived natural substances as immunomodulatory agents in carcinogenesis. \textit{Journal of cancer research and clinical oncology}. Germany: Springer-Verlag, 2020, roč.~146, č.~12, s.~3137-3154. ISSN~0171-5216. Dostupné z: https://dx.doi.org/10.1007/s00432-020-03424-2.

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