Fecundity-Longevity Trade-Off, Vertical Transmission, and
Evolution of Virulence in Sterilizing Pathogens

J 2020

Fecundity-Longevity Trade-Off, Vertical Transmission, and Evolution of Virulence in Sterilizing Pathogens

JANOUŠKOVÁ, Eva a Luděk BEREC

Základní údaje

Originální název

Fecundity-Longevity Trade-Off, Vertical Transmission, and Evolution of Virulence in Sterilizing Pathogens

Autoři

JANOUŠKOVÁ, Eva a Luděk BEREC

Vydání

The American Naturalist, Chicago, University of Chicago Press, 2020, 0003-0147

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10103 Statistics and probability

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.926

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/20:00117095

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

adaptive dynamics; evolutionary branching; fecundity reduction; infectious disease; mathematical model; sterilization

Štítky

14311010, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 25. 11. 2020 14:27, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

Sterilizing pathogens are common, yet studies focused on how such pathogens respond adaptively to fecundity reductions caused in their hosts are rare. Here we assume that the infected hosts, as a result of redistributing energy resources saved by reduced fecundity, have increased longevity and focus on exploring the consequences of such a fecundity-longevity trade-off on sterility virulence evolution in the pathogens. We find that the trade-off itself cannot prevent the evolution of full sterilization. Therefore, we allow for vertical transmission and reveal that the fecundity-longevity trade-off strongly determines the threshold efficiency of vertical transmission above which partial host sterilization evolves. Partial sterilization may appear as an intermediate level of sterility virulence or as a stable dimorphism at which avirulent and highly virulent strains coexist. The fecundity-longevity trade-off significantly contributes to determining the actual outcome, in many cases countering predictions made in the absence of this trade-off. It is known that in well-mixed populations, partial sterilization may evolve in pathogens under a combination of horizontal and vertical transmission. Our study highlights that this is independent of the form of horizontal transmission and the type of density dependence in host demography and that the fecundity-longevity trade-off is an important player in sterility virulence evolution.

Návaznosti

MUNI/A/1503/2018, interní kód MU

Název: Matematické statistické modelování 3 (Akronym: MaStaMo3)

Investor: Masarykova univerzita, Matematické statistické modelování 3, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

JANOUŠKOVÁ, Eva a Luděk BEREC. Fecundity-Longevity Trade-Off, Vertical Transmission, and Evolution of Virulence in Sterilizing Pathogens. The American Naturalist. Chicago: University of Chicago Press, 2020, roč. 195, č. 1, s. 95-106. ISSN 0003-0147. Dostupné z: https://doi.org/10.1086/706182.

@article{1699459,
   author = {Janoušková, Eva and Berec, Luděk},
   article_location = {Chicago},
   article_number = {1},
   doi = {https://doi.org/10.1086/706182},
   keywords = {adaptive dynamics; evolutionary branching; fecundity reduction; infectious disease; mathematical model; sterilization},
   language = {eng},
   issn = {0003-0147},
   journal = {The American Naturalist},
   title = {Fecundity-Longevity Trade-Off, Vertical Transmission, and Evolution of Virulence in Sterilizing Pathogens},
   url = {https://www.journals.uchicago.edu/doi/full/10.1086/706182},
   volume = {195},
   year = {2020}
}

TY  - JOUR
ID  - 1699459
AU  - Janoušková, Eva - Berec, Luděk
PY  - 2020
TI  - Fecundity-Longevity Trade-Off, Vertical Transmission, and Evolution of Virulence in Sterilizing Pathogens
JF  - The American Naturalist
VL  - 195
IS  - 1
SP  - 95-106
EP  - 95-106
PB  - University of Chicago Press
SN  - 00030147
KW  - adaptive dynamics
KW  - evolutionary branching
KW  - fecundity reduction
KW  - infectious disease
KW  - mathematical model
KW  - sterilization
UR  - https://www.journals.uchicago.edu/doi/full/10.1086/706182
L2  - https://www.journals.uchicago.edu/doi/full/10.1086/706182
N2  - Sterilizing pathogens are common, yet studies focused on how such pathogens respond adaptively to fecundity reductions caused in their hosts are rare. Here we assume that the infected hosts, as a result of redistributing energy resources saved by reduced fecundity, have increased longevity and focus on exploring the consequences of such a fecundity-longevity trade-off on sterility virulence evolution in the pathogens. We find that the trade-off itself cannot prevent the evolution of full sterilization. Therefore, we allow for vertical transmission and reveal that the fecundity-longevity trade-off strongly determines the threshold efficiency of vertical transmission above which partial host sterilization evolves. Partial sterilization may appear as an intermediate level of sterility virulence or as a stable dimorphism at which avirulent and highly virulent strains coexist. The fecundity-longevity trade-off significantly contributes to determining the actual outcome, in many cases countering predictions made in the absence of this trade-off. It is known that in well-mixed populations, partial sterilization may evolve in pathogens under a combination of horizontal and vertical transmission. Our study highlights that this is independent of the form of horizontal transmission and the type of density dependence in host demography and that the fecundity-longevity trade-off is an important player in sterility virulence evolution.
ER  -

JANOUŠKOVÁ, Eva a Luděk BEREC. Fecundity-Longevity Trade-Off, Vertical Transmission, and Evolution of Virulence in Sterilizing Pathogens. \textit{The American Naturalist}. Chicago: University of Chicago Press, 2020, roč.~195, č.~1, s.~95-106. ISSN~0003-0147. Dostupné z: https://doi.org/10.1086/706182.

Přehled o publikaci