The first mitochondrial genomes of endosymbiotic rhabdocoels
illustrate evolutionary relaxation of atp8 and genome
plasticity in flatworms

J 2020

The first mitochondrial genomes of endosymbiotic rhabdocoels illustrate evolutionary relaxation of atp8 and genome plasticity in flatworms

MONNENS, Marlies; Sofie THIJS; Andrew G. BRISCOE; Miriam CLARK; Emily Joy FROST et al.

Základní údaje

Originální název

The first mitochondrial genomes of endosymbiotic rhabdocoels illustrate evolutionary relaxation of atp8 and genome plasticity in flatworms

Autoři

MONNENS, Marlies; Sofie THIJS; Andrew G. BRISCOE; Miriam CLARK; Emily Joy FROST; D. Tim J. LITTLEWOOD; Mary SEWELL; Karen SMEETS; Tom ARTOIS a Maarten Pieterjan VANHOVE

Vydání

International journal of biological macromolecules, Amsterdam, Elsevier, 2020, 0141-8130

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10613 Zoology

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 6.953

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/20:00117251

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

Platyhelminthes; Rhabdocoela; Genomics; Endosymbiosis; Mitochondrion

Štítky

14314020, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 7. 12. 2020 13:24, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

The first three mitochondrial (mt) genomes of endosymbiotic turbellarian flatworms are characterised for the rhabdocoels Graffilla buccinicola, Syndesmis echinorum and S. kurakaikina. Interspecific comparison of the three newly obtained sequences and the only previously characterised rhabdocoel, the free-living species Bothromesostoma personatum, reveals high mt genomic variability, including numerous rearrangements. The first intrageneric comparison within rhabdocoels shows that gene order is not fully conserved even between congeneric species. Atp8, until recently assumed absent in flatworms, was putatively annotated in two sequences. Selection pressure was tested in a phylogenetic framework and is shown to be significantly relaxed in this and another protein-coding gene: cox1. If present, atp8 appears highly derived in platyhelminths and its functionality needs to be addressed in future research. Our findings for the first time allude to a large degree of undiscovered (mt) genomic plasticity in rhabdocoels. It merits further attention whether this variation is correlated with a symbiotic lifestyle. Our results illustrate that this phenomenon is widespread in flatworms as a whole and not exclusive to the better-studied neodermatans.

Citovat

MONNENS, Marlies; Sofie THIJS; Andrew G. BRISCOE; Miriam CLARK; Emily Joy FROST; D. Tim J. LITTLEWOOD; Mary SEWELL; Karen SMEETS; Tom ARTOIS a Maarten Pieterjan VANHOVE. The first mitochondrial genomes of endosymbiotic rhabdocoels illustrate evolutionary relaxation of atp8 and genome plasticity in flatworms. International journal of biological macromolecules. Amsterdam: Elsevier, 2020, roč. 162, November 2020, s. 454-469. ISSN 0141-8130. Dostupné z: https://doi.org/10.1016/j.ijbiomac.2020.06.025.

@article{1705296,
   author = {Monnens, Marlies and Thijs, Sofie and Briscoe, Andrew G. and Clark, Miriam and Frost, Emily Joy and Littlewood, D. Tim J. and Sewell, Mary and Smeets, Karen and Artois, Tom and Vanhove, Maarten Pieterjan},
   article_location = {Amsterdam},
   article_number = {November 2020},
   doi = {https://doi.org/10.1016/j.ijbiomac.2020.06.025},
   keywords = {Platyhelminthes; Rhabdocoela; Genomics; Endosymbiosis; Mitochondrion},
   language = {eng},
   issn = {0141-8130},
   journal = {International journal of biological macromolecules},
   title = {The first mitochondrial genomes of endosymbiotic rhabdocoels illustrate evolutionary relaxation of atp8 and genome plasticity in flatworms},
   url = {https://doi.org/10.1016/j.ijbiomac.2020.06.025},
   volume = {162},
   year = {2020}
}

TY  - JOUR
ID  - 1705296
AU  - Monnens, Marlies - Thijs, Sofie - Briscoe, Andrew G. - Clark, Miriam - Frost, Emily Joy - Littlewood, D. Tim J. - Sewell, Mary - Smeets, Karen - Artois, Tom - Vanhove, Maarten Pieterjan
PY  - 2020
TI  - The first mitochondrial genomes of endosymbiotic rhabdocoels illustrate evolutionary relaxation of atp8 and genome plasticity in flatworms
JF  - International journal of biological macromolecules
VL  - 162
IS  - November 2020
SP  - 454-469
EP  - 454-469
PB  - Elsevier
SN  - 01418130
KW  - Platyhelminthes
KW  - Rhabdocoela
KW  - Genomics
KW  - Endosymbiosis
KW  - Mitochondrion
UR  - https://doi.org/10.1016/j.ijbiomac.2020.06.025
L2  - https://doi.org/10.1016/j.ijbiomac.2020.06.025
N2  - The first three mitochondrial (mt) genomes of endosymbiotic turbellarian flatworms are characterised for the rhabdocoels Graffilla buccinicola, Syndesmis echinorum and S. kurakaikina. Interspecific comparison of the three newly obtained sequences and the only previously characterised rhabdocoel, the free-living species Bothromesostoma personatum, reveals high mt genomic variability, including numerous rearrangements. The first intrageneric comparison within rhabdocoels shows that gene order is not fully conserved even between congeneric species. Atp8, until recently assumed absent in flatworms, was putatively annotated in two sequences. Selection pressure was tested in a phylogenetic framework and is shown to be significantly relaxed in this and another protein-coding gene: cox1. If present, atp8 appears highly derived in platyhelminths and its functionality needs to be addressed in future research. Our findings for the first time allude to a large degree of undiscovered (mt) genomic plasticity in rhabdocoels. It merits further attention whether this variation is correlated with a symbiotic lifestyle. Our results illustrate that this phenomenon is widespread in flatworms as a whole and not exclusive to the better-studied neodermatans.
ER  -

MONNENS, Marlies; Sofie THIJS; Andrew G. BRISCOE; Miriam CLARK; Emily Joy FROST; D. Tim J. LITTLEWOOD; Mary SEWELL; Karen SMEETS; Tom ARTOIS a Maarten Pieterjan VANHOVE. The first mitochondrial genomes of endosymbiotic rhabdocoels illustrate evolutionary relaxation of atp8 and genome plasticity in flatworms. \textit{International journal of biological macromolecules}. Amsterdam: Elsevier, 2020, roč.~162, November 2020, s.~454-469. ISSN~0141-8130. Dostupné z: https://doi.org/10.1016/j.ijbiomac.2020.06.025.

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