| JELÍNEK, Matyáš, Michal JURAJDA a Kamil ĎURIŠ. The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage. Oxidative Medicine and Cellular Longevity. London: HINDAWI LTD, 2020, roč. 2020, NOV 2020, s. 1-9. ISSN 1942-0900. Dostupné z: https://dx.doi.org/10.1155/2020/8877116. |
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@article{1718796,
author = {Jelínek, Matyáš and Jurajda, Michal and Ďuriš, Kamil},
article_location = {London},
article_number = {NOV 2020},
doi = {http://dx.doi.org/10.1155/2020/8877116},
keywords = {Oxidative Stress; Early Brain Injury; Subarachnoid Hemorrhage},
language = {eng},
issn = {1942-0900},
journal = {Oxidative Medicine and Cellular Longevity},
title = {The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage},
url = {https://www.hindawi.com/journals/omcl/2020/8877116/},
volume = {2020},
year = {2020}
}
TY - JOUR
ID - 1718796
AU - Jelínek, Matyáš - Jurajda, Michal - Ďuriš, Kamil
PY - 2020
TI - The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage
JF - Oxidative Medicine and Cellular Longevity
VL - 2020
IS - NOV 2020
SP - 1-9
EP - 1-9
PB - HINDAWI LTD
SN - 19420900
KW - Oxidative Stress
KW - Early Brain Injury
KW - Subarachnoid Hemorrhage
UR - https://www.hindawi.com/journals/omcl/2020/8877116/
L2 - https://www.hindawi.com/journals/omcl/2020/8877116/
N2 - This review focuses on the problem of oxidative stress in early brain injury (EBI) after spontaneous subarachnoid hemorrhage (SAH). EBI involves complex pathophysiological mechanisms, including oxidative stress. In the first section, we describe the main sources of free radicals in EBI. There are several sources of excessive generation of free radicals from mitochondrial free radicals' generation and endoplasmic reticulum stress, to hemoglobin and enzymatic free radicals' generation. The second part focuses on the disruption of antioxidant mechanisms in EBI. The third section describes some newly found molecular mechanisms and pathway involved in oxidative stress after EBI. The last section is dedicated to the pathophysiological mechanisms through which free radicals mediate early brain injury.
ER -
JELÍNEK, Matyáš, Michal JURAJDA a Kamil ĎURIŠ. The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage. \textit{Oxidative Medicine and Cellular Longevity}. London: HINDAWI LTD, 2020, roč.~2020, NOV 2020, s.~1-9. ISSN~1942-0900. Dostupné z: https://dx.doi.org/10.1155/2020/8877116.
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