Impact of COVID-19 Pandemic on Mechanical Reperfusion for Patients With STEMI
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DE LUCA, G.; M. VERDOIA; M. CERCEK; L. O. JENSEN; M. VAVLUKIS; L. CALMAC; T. JOHNSON; G. R. FERRER; V. GANYUKOV; W. WOJAKOWSKI; T. KINNAIRD; C. VAN BIRGELEN; Y. COTTIN; A. IJSSELMUIDEN; B. TUCCILLO; F. VERSACI; K. J . ROYAARDS; J. TEN BERG; M. LAINE; M. DIRKSEN; M. SIVIGLIA; G. CASELLA; Petr KALA; J. L. D. GIL; A. BANNING; V. BECERRA; C. DE SIMONE; A. SANTUCCI; X. CARRILLO; A. SCOCCIA; G. AMOROSO; A. LUX; T. KOVARNIK; P. DAVLOUROS; J. MEHILLI; G. GABRIELLI; X. F. RIOS; N. BAKRACESKI; S. LEVESQUE; G. CIRRINCIONE; V. GUIDUCCI; M. KIDAWA; L. SPEDICATO; L. MARINUCCI; P. LUDMAN; F. ZILIO; G. GALASSO; E. FABRIS; M. MENICHELLI; A. GARCIA-TOUCHARD; S. MANZO; G. CAIAZZO; J. MOREU; J. S. FORES; L. DONAZZAN; L. VIGNALI; R. TELES; E. BENIT; P. AGOSTONI; F. B. OJEDA; H. LEHTOLA; S. CAMACHO-FREIERE; A. KRAAIJEVELD; Y. ANTTI; M. BOCCALATTE; P. DEHARO; I. L. MARTINEZ-LUENGAS; B. SCHELLER; D. ALEXOPOULOS; R. MORENO; E. KEDHI; G. UCCELLO; B. FAURIE; A. G. BARRIOS; F. S. DI UCCIO; B. WILBERT; P. SMITS; G. CORTESE; G. PARODI a D. DUDEK
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Journal of the American College of Cardiology, New York, Elsevier Science INC, 2020, 0735-1097
BACKGROUND The fear of contagion during the coronavirus disease-2019 (COVID-19) pandemic may have potentially refrained patients with ST-segment elevation myocardial infarction (STEMI) from accessing the emergency system, with subsequent impact on mortality. OBJECTIVES The ISACS-STEMI COVID-19 registry aims to estimate the true impact of the COVID-19 pandemic on the treatment and outcome of patients with STEMI treated by primary percutaneous coronary intervention (PPCI), with identification of "at-risk" patient cohorts for failure to present or delays to treatment. METHODS This retrospective registry was performed in European high-volume PPCI centers and assessed patients with STEMI treated with PPPCI in March/April 2019 and 2020. Main outcomes are the incidences of PPCI, delayed treatment, and in-hospital mortality. RESULTS A total of 6,609 patients underwent PPCI in 77 centers, located in 18 countries. In 2020, during the pandemic, there was a significant reduction in PPCI as compared with 2019 (incidence rate ratio: 0.811; 95% confidence interval: 0.78 to 0.84; p < 0.0001). The heterogeneity among centers was not related to the incidence of death due to COVID-19. A significant interaction was observed for patients with arterial hypertension, who were less frequently admitted in 2020 than in 2019. Furthermore, the pandemic was associated with a significant increase in door-to-balloon and total ischemia times, which may have contributed to the higher mortality during the pandemic. CONCLUSIONS The COVID-19 pandemic had significant impact on the treatment of patients with STEMI, with a 19% reduction in PPCI procedures, especially among patients suffering from hypertension, and a longer delay to treatment, which may have contributed to the increased mortality during the pandemic. (C) 2020 by the American College of Cardiology Foundation.
DE LUCA, G.; M. VERDOIA; M. CERCEK; L. O. JENSEN; M. VAVLUKIS; L. CALMAC; T. JOHNSON; G. R. FERRER; V. GANYUKOV; W. WOJAKOWSKI; T. KINNAIRD; C. VAN BIRGELEN; Y. COTTIN; A. IJSSELMUIDEN; B. TUCCILLO; F. VERSACI; K. J . ROYAARDS; J. TEN BERG; M. LAINE; M. DIRKSEN; M. SIVIGLIA; G. CASELLA; Petr KALA; J. L. D. GIL; A. BANNING; V. BECERRA; C. DE SIMONE; A. SANTUCCI; X. CARRILLO; A. SCOCCIA; G. AMOROSO; A. LUX; T. KOVARNIK; P. DAVLOUROS; J. MEHILLI; G. GABRIELLI; X. F. RIOS; N. BAKRACESKI; S. LEVESQUE; G. CIRRINCIONE; V. GUIDUCCI; M. KIDAWA; L. SPEDICATO; L. MARINUCCI; P. LUDMAN; F. ZILIO; G. GALASSO; E. FABRIS; M. MENICHELLI; A. GARCIA-TOUCHARD; S. MANZO; G. CAIAZZO; J. MOREU; J. S. FORES; L. DONAZZAN; L. VIGNALI; R. TELES; E. BENIT; P. AGOSTONI; F. B. OJEDA; H. LEHTOLA; S. CAMACHO-FREIERE; A. KRAAIJEVELD; Y. ANTTI; M. BOCCALATTE; P. DEHARO; I. L. MARTINEZ-LUENGAS; B. SCHELLER; D. ALEXOPOULOS; R. MORENO; E. KEDHI; G. UCCELLO; B. FAURIE; A. G. BARRIOS; F. S. DI UCCIO; B. WILBERT; P. SMITS; G. CORTESE; G. PARODI a D. DUDEK. Impact of COVID-19 Pandemic on Mechanical Reperfusion for Patients With STEMI. Journal of the American College of Cardiology. New York: Elsevier Science INC, 2020, roč. 76, č. 20, s. 2321-2330. ISSN 0735-1097. Dostupné z: https://doi.org/10.1016/j.jacc.2020.09.546.
@article{1726157, author = {De Luca, G. and Verdoia, M. and Cercek, M. and Jensen, L. O. and Vavlukis, M. and Calmac, L. and Johnson, T. and Ferrer, G. R. and Ganyukov, V. and Wojakowski, W. and Kinnaird, T. and van Birgelen, C. and Cottin, Y. and IJsselmuiden, A. and Tuccillo, B. and Versaci, F. and Royaards, K. J . and Ten Berg, J. and Laine, M. and Dirksen, M. and Siviglia, M. and Casella, G. and Kala, Petr and Gil, J. L. D. and Banning, A. and Becerra, V. and De Simone, C. and Santucci, A. and Carrillo, X. and Scoccia, A. and Amoroso, G. and Lux, A. and Kovarnik, T. and Davlouros, P. and Mehilli, J. and Gabrielli, G. and Rios, X. F. and Bakraceski, N. and Levesque, S. and Cirrincione, G. and Guiducci, V. and Kidawa, M. and Spedicato, L. and Marinucci, L. and Ludman, P. and Zilio, F. and Galasso, G. and Fabris, E. and Menichelli, M. and GarciaandTouchard, A. and Manzo, S. and Caiazzo, G. and Moreu, J. and Fores, J. S. and Donazzan, L. and Vignali, L. and Teles, R. and Benit, E. and Agostoni, P. and Ojeda, F. B. and Lehtola, H. and CamachoandFreiere, S. and Kraaijeveld, A. and Antti, Y. and Boccalatte, M. and Deharo, P. and MartinezandLuengas, I. L. and Scheller, B. and Alexopoulos, D. and Moreno, R. and Kedhi, E. and Uccello, G. and Faurie, B. and Barrios, A. G. and Di Uccio, F. S. and Wilbert, B. and Smits, P. and Cortese, G. and Parodi, G. and Dudek, D.}, article_location = {New York}, article_number = {20}, doi = {https://doi.org/10.1016/j.jacc.2020.09.546}, keywords = {COVID-19; primary angioplasty; STEMI}, language = {eng}, issn = {0735-1097}, journal = {Journal of the American College of Cardiology}, title = {Impact of COVID-19 Pandemic on Mechanical Reperfusion for Patients With STEMI}, url = {https://www.sciencedirect.com/science/article/pii/S0735109720372399?via%3Dihub}, volume = {76}, year = {2020} }
TY - JOUR ID - 1726157 AU - De Luca, G. - Verdoia, M. - Cercek, M. - Jensen, L. O. - Vavlukis, M. - Calmac, L. - Johnson, T. - Ferrer, G. R. - Ganyukov, V. - Wojakowski, W. - Kinnaird, T. - van Birgelen, C. - Cottin, Y. - IJsselmuiden, A. - Tuccillo, B. - Versaci, F. - Royaards, K. J . - Ten Berg, J. - Laine, M. - Dirksen, M. - Siviglia, M. - Casella, G. - Kala, Petr - Gil, J. L. D. - Banning, A. - Becerra, V. - De Simone, C. - Santucci, A. - Carrillo, X. - Scoccia, A. - Amoroso, G. - Lux, A. - Kovarnik, T. - Davlouros, P. - Mehilli, J. - Gabrielli, G. - Rios, X. F. - Bakraceski, N. - Levesque, S. - Cirrincione, G. - Guiducci, V. - Kidawa, M. - Spedicato, L. - Marinucci, L. - Ludman, P. - Zilio, F. - Galasso, G. - Fabris, E. - Menichelli, M. - Garcia-Touchard, A. - Manzo, S. - Caiazzo, G. - Moreu, J. - Fores, J. S. - Donazzan, L. - Vignali, L. - Teles, R. - Benit, E. - Agostoni, P. - Ojeda, F. B. - Lehtola, H. - Camacho-Freiere, S. - Kraaijeveld, A. - Antti, Y. - Boccalatte, M. - Deharo, P. - Martinez-Luengas, I. L. - Scheller, B. - Alexopoulos, D. - Moreno, R. - Kedhi, E. - Uccello, G. - Faurie, B. - Barrios, A. G. - Di Uccio, F. S. - Wilbert, B. - Smits, P. - Cortese, G. - Parodi, G. - Dudek, D. PY - 2020 TI - Impact of COVID-19 Pandemic on Mechanical Reperfusion for Patients With STEMI JF - Journal of the American College of Cardiology VL - 76 IS - 20 SP - 2321-2330 EP - 2321-2330 PB - Elsevier Science INC SN - 07351097 KW - COVID-19 KW - primary angioplasty KW - STEMI UR - https://www.sciencedirect.com/science/article/pii/S0735109720372399?via%3Dihub L2 - https://www.sciencedirect.com/science/article/pii/S0735109720372399?via%3Dihub N2 - BACKGROUND The fear of contagion during the coronavirus disease-2019 (COVID-19) pandemic may have potentially refrained patients with ST-segment elevation myocardial infarction (STEMI) from accessing the emergency system, with subsequent impact on mortality. OBJECTIVES The ISACS-STEMI COVID-19 registry aims to estimate the true impact of the COVID-19 pandemic on the treatment and outcome of patients with STEMI treated by primary percutaneous coronary intervention (PPCI), with identification of "at-risk" patient cohorts for failure to present or delays to treatment. METHODS This retrospective registry was performed in European high-volume PPCI centers and assessed patients with STEMI treated with PPPCI in March/April 2019 and 2020. Main outcomes are the incidences of PPCI, delayed treatment, and in-hospital mortality. RESULTS A total of 6,609 patients underwent PPCI in 77 centers, located in 18 countries. In 2020, during the pandemic, there was a significant reduction in PPCI as compared with 2019 (incidence rate ratio: 0.811; 95% confidence interval: 0.78 to 0.84; p < 0.0001). The heterogeneity among centers was not related to the incidence of death due to COVID-19. A significant interaction was observed for patients with arterial hypertension, who were less frequently admitted in 2020 than in 2019. Furthermore, the pandemic was associated with a significant increase in door-to-balloon and total ischemia times, which may have contributed to the higher mortality during the pandemic. CONCLUSIONS The COVID-19 pandemic had significant impact on the treatment of patients with STEMI, with a 19% reduction in PPCI procedures, especially among patients suffering from hypertension, and a longer delay to treatment, which may have contributed to the increased mortality during the pandemic. (C) 2020 by the American College of Cardiology Foundation. ER -
DE LUCA, G.; M. VERDOIA; M. CERCEK; L. O. JENSEN; M. VAVLUKIS; L. CALMAC; T. JOHNSON; G. R. FERRER; V. GANYUKOV; W. WOJAKOWSKI; T. KINNAIRD; C. VAN BIRGELEN; Y. COTTIN; A. IJSSELMUIDEN; B. TUCCILLO; F. VERSACI; K. J . ROYAARDS; J. TEN BERG; M. LAINE; M. DIRKSEN; M. SIVIGLIA; G. CASELLA; Petr KALA; J. L. D. GIL; A. BANNING; V. BECERRA; C. DE SIMONE; A. SANTUCCI; X. CARRILLO; A. SCOCCIA; G. AMOROSO; A. LUX; T. KOVARNIK; P. DAVLOUROS; J. MEHILLI; G. GABRIELLI; X. F. RIOS; N. BAKRACESKI; S. LEVESQUE; G. CIRRINCIONE; V. GUIDUCCI; M. KIDAWA; L. SPEDICATO; L. MARINUCCI; P. LUDMAN; F. ZILIO; G. GALASSO; E. FABRIS; M. MENICHELLI; A. GARCIA-TOUCHARD; S. MANZO; G. CAIAZZO; J. MOREU; J. S. FORES; L. DONAZZAN; L. VIGNALI; R. TELES; E. BENIT; P. AGOSTONI; F. B. OJEDA; H. LEHTOLA; S. CAMACHO-FREIERE; A. KRAAIJEVELD; Y. ANTTI; M. BOCCALATTE; P. DEHARO; I. L. MARTINEZ-LUENGAS; B. SCHELLER; D. ALEXOPOULOS; R. MORENO; E. KEDHI; G. UCCELLO; B. FAURIE; A. G. BARRIOS; F. S. DI UCCIO; B. WILBERT; P. SMITS; G. CORTESE; G. PARODI a D. DUDEK. Impact of COVID-19 Pandemic on Mechanical Reperfusion for Patients With STEMI. \textit{Journal of the American College of Cardiology}. New York: Elsevier Science INC, 2020, roč.~76, č.~20, s.~2321-2330. ISSN~0735-1097. Dostupné z: https://doi.org/10.1016/j.jacc.2020.09.546.