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@article{1726783,
author = {Kubínová, Renata and Švajdlenka, Emil and Jankovská, Dagmar},
article_location = {ABINGDON},
article_number = {10},
doi = {http://dx.doi.org/10.1080/14786419.2015.1043552},
keywords = {Agrimonia species; flavonoids; polyphenols; antioxidant activity; cholinesterase inhibition},
language = {eng},
issn = {1478-6419},
journal = {NATURAL PRODUCT RESEARCH},
title = {Anticholinesterase, antioxidant activity and phytochemical investigation into aqueous extracts from five species of Agrimonia genus},
volume = {30},
year = {2016}
}
TY - JOUR
ID - 1726783
AU - Kubínová, Renata - Švajdlenka, Emil - Jankovská, Dagmar
PY - 2016
TI - Anticholinesterase, antioxidant activity and phytochemical investigation into aqueous extracts from five species of Agrimonia genus
JF - NATURAL PRODUCT RESEARCH
VL - 30
IS - 10
SP - 1174-1177
EP - 1174-1177
PB - TAYLOR & FRANCIS LTD
SN - 14786419
KW - Agrimonia species
KW - flavonoids
KW - polyphenols
KW - antioxidant activity
KW - cholinesterase inhibition
N2 - Aqueous extracts of aerial flowering parts of five Agrimonia species (Rosaceae): Agrimonia coreana Nakai, Agrimonia japonica (Miq.) Koidz, Agrimonia procera Wallr., Agrimonia eupatoria L. and Agrimonia leucantha Kunze were investigated on their antioxidant activity, measured using five different methods; the best was the extract from A. procera with IC50 values from 6 to 29g/mL. All the extracts displayed inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) at the tested concentration of 100g/mL. We found the highest inhibition of cholinesterase in the extract of A. japonica with inhibition 70.4% for AChE and 79.8% for BuChE. These findings are statistically significant in comparison with those of other extracts (p<0.001). The phytochemical analyses showed that the antioxidant activity of Agrimonia extracts can be affected especially by hexahydroxydiphenoyl (HHDP)-glucose and quercetin glycosides, and inhibition of cholinesterases by apigenin, luteolin and quercetin glycosides.
ER -
KUBÍNOVÁ, Renata, Emil ŠVAJDLENKA a Dagmar JANKOVSKÁ. Anticholinesterase, antioxidant activity and phytochemical investigation into aqueous extracts from five species of Agrimonia genus. \textit{NATURAL PRODUCT RESEARCH}. ABINGDON: TAYLOR \&{}amp; FRANCIS LTD, 2016, roč.~30, č.~10, s.~1174-1177. ISSN~1478-6419. Dostupné z: https://dx.doi.org/10.1080/14786419.2015.1043552.
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