Antioxidant potential of some natural and semi-synthetic
flavonoid derivatives and the extracts from Maclura pomifera
(Rafin.) Schneider (osage orange) and its essential oil
composition

J 2016

Antioxidant potential of some natural and semi-synthetic flavonoid derivatives and the extracts from Maclura pomifera (Rafin.) Schneider (osage orange) and its essential oil composition

ORHAN, I.E.; F.S. SENOL; B. DEMIRCI; Margita DVORSKÁ; Karel ŠMEJKAL et al.

Základní údaje

Originální název

Antioxidant potential of some natural and semi-synthetic flavonoid derivatives and the extracts from Maclura pomifera (Rafin.) Schneider (osage orange) and its essential oil composition

Autoři

ORHAN, I.E.; F.S. SENOL; B. DEMIRCI; Margita DVORSKÁ; Karel ŠMEJKAL a Milan ŽEMLIČKA

Vydání

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, TURKEY, WALTER DE GRUYTER GMBH, 2016, 0250-4685

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30104 Pharmacology and pharmacy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 0.216

Označené pro přenos do RIV

Organizační jednotka

Farmaceutická fakulta

Klíčová slova anglicky

Maclura pomifera; Antioxidant; Osajin; Pomiferin; Macluraxanthone; Essential oil

Změněno: 28. 7. 2022 11:59, PharmDr. Margita Dvorská, Ph.D.

Anotace

V originále

Objective: The antioxidant potential of various extracts were obtained from the leaf and fruit of Maclura pomifera (Rafin.) Schneider (Moraceae) along with its major isoflavonoids; osajin and pomiferin, their semi-synthetic derivatives; iso-osajin and iso-pomiferin and macluraxanthone, which were assayed. Methods: The extracts and compounds were subjected to six experimental models including 2,2'-diphenyl-1-picrylhydrazyl (DPPH), N, N-dimethyl-p-phenylendiamine (DMPD+), and nitric oxide (NO) radical scavenging activity, metal-chelating capacity, ferric-(FRAP) and phosphomolibdenum- reducing antioxidant power (PRAP) assays by using ELISA methods. Results: The fruit aqueous extract exerted higher scavenging activity against DMPD and NO radicals, while the fruit ethyl acetate extract was the most active against DPPH radical (68.61 +/- 2.53%). Among the tested compounds, the highest DPPH (91.74 +/- 0.26%) and DMPD (30.63 +/- 1.31%) radical scavenging effect was observed with macluraxanthone, while pomiferin and iso-pomiferin exhibited better activity than osajin and iso-osajin in all assays except the metal-chelation capacity assay. Phytol was the major compound in both the leaf oils, while the fruit essential oil contained beta-caryophyllene as the main component (69.3%). Discussion and Conclusion: The current study covers particularly antioxidant capacity of iso-osajin, iso-pomiferin, and macluraxanthone by the aforementioned methods and, among them; pomiferin seems to be a natural possible antioxidant agent.

Citovat

ORHAN, I.E.; F.S. SENOL; B. DEMIRCI; Margita DVORSKÁ; Karel ŠMEJKAL a Milan ŽEMLIČKA. Antioxidant potential of some natural and semi-synthetic flavonoid derivatives and the extracts from Maclura pomifera (Rafin.) Schneider (osage orange) and its essential oil composition. TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI. TURKEY: WALTER DE GRUYTER GMBH, 2016, roč. 41, č. 6, s. 403-411. ISSN 0250-4685. Dostupné z: https://doi.org/10.1515/tjb-2016-0125.

@article{1726833,
   author = {Orhan, I.E. and Senol, F.S. and Demirci, B. and Dvorská, Margita and Šmejkal, Karel and Žemlička, Milan},
   article_location = {TURKEY},
   article_number = {6},
   doi = {https://doi.org/10.1515/tjb-2016-0125},
   keywords = {Maclura pomifera; Antioxidant; Osajin; Pomiferin; Macluraxanthone; Essential oil},
   language = {eng},
   issn = {0250-4685},
   journal = {TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI},
   title = {Antioxidant potential of some natural and semi-synthetic flavonoid derivatives and the extracts from Maclura pomifera (Rafin.) Schneider (osage orange) and its essential oil composition},
   volume = {41},
   year = {2016}
}

TY  - JOUR
ID  - 1726833
AU  - Orhan, I.E. - Senol, F.S. - Demirci, B. - Dvorská, Margita - Šmejkal, Karel - Žemlička, Milan
PY  - 2016
TI  - Antioxidant potential of some natural and semi-synthetic flavonoid derivatives and the extracts from Maclura pomifera (Rafin.) Schneider (osage orange) and its essential oil composition
JF  - TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
VL  - 41
IS  - 6
SP  - 403-411
EP  - 403-411
PB  - WALTER DE GRUYTER GMBH
SN  - 02504685
KW  - Maclura pomifera
KW  - Antioxidant
KW  - Osajin
KW  - Pomiferin
KW  - Macluraxanthone
KW  - Essential oil
N2  - Objective: The antioxidant potential of various extracts were obtained from the leaf and fruit of Maclura pomifera (Rafin.) Schneider (Moraceae) along with its major isoflavonoids; osajin and pomiferin, their semi-synthetic derivatives; iso-osajin and iso-pomiferin and macluraxanthone, which were assayed. Methods: The extracts and compounds were subjected to six experimental models including 2,2'-diphenyl-1-picrylhydrazyl (DPPH), N, N-dimethyl-p-phenylendiamine (DMPD+), and nitric oxide (NO) radical scavenging activity, metal-chelating capacity, ferric-(FRAP) and phosphomolibdenum- reducing antioxidant power (PRAP) assays by using ELISA methods. Results: The fruit aqueous extract exerted higher scavenging activity against DMPD and NO radicals, while the fruit ethyl acetate extract was the most active against DPPH radical (68.61 +/- 2.53%). Among the tested compounds, the highest DPPH (91.74 +/- 0.26%) and DMPD (30.63 +/- 1.31%) radical scavenging effect was observed with macluraxanthone, while pomiferin and iso-pomiferin exhibited better activity than osajin and iso-osajin in all assays except the metal-chelation capacity assay. Phytol was the major compound in both the leaf oils, while the fruit essential oil contained beta-caryophyllene as the main component (69.3%). Discussion and Conclusion: The current study covers particularly antioxidant capacity of iso-osajin, iso-pomiferin, and macluraxanthone by the aforementioned methods and, among them; pomiferin seems to be a natural possible antioxidant agent.
ER  -

ORHAN, I.E.; F.S. SENOL; B. DEMIRCI; Margita DVORSKÁ; Karel ŠMEJKAL a Milan ŽEMLIČKA. Antioxidant potential of some natural and semi-synthetic flavonoid derivatives and the extracts from Maclura pomifera (Rafin.) Schneider (osage orange) and its essential oil composition. \textit{TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI}. TURKEY: WALTER DE GRUYTER GMBH, 2016, roč.~41, č.~6, s.~403-411. ISSN~0250-4685. Dostupné z: https://doi.org/10.1515/tjb-2016-0125.

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