Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and
Pharmacological Activity

J 2019

Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity

MALANÍK, Milan; Jakub TREML; Veronika RJAŠKOVÁ; Karolína TÍŽKOVÁ; Petra KAUCKÁ et al.

Základní údaje

Originální název

Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity

Autoři

MALANÍK, Milan; Jakub TREML; Veronika RJAŠKOVÁ; Karolína TÍŽKOVÁ; Petra KAUCKÁ; Ladislav KOKOŠKA; Peter KUBATKA a Karel ŠMEJKAL

Vydání

Molecules, BASEL, MDPI, 2019, 1420-3049

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30104 Pharmacology and pharmacy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 3.267

Označené pro přenos do RIV

Organizační jednotka

Farmaceutická fakulta

Klíčová slova anglicky

dihydro-beta-agarofuran sesquiterpene; folk medicine; Maytenus macrocarpa; rheumatism; triterpene

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 16. 3. 2021 11:28, PharmDr. Milan Malaník, Ph.D.

Anotace

V originále

Maytenus macrocarpa (Celastraceae) is a tree native to Amazonia. Its roots, leaves, bark, and combinations of these are used in traditional medicine mainly to treat rheumatism and, to a lesser extent, to heal wounds and to combat bronchitis and diarrhea. To date, mainly triterpenes and dihydro-beta-agarofuran sesquiterpenes were isolated from M. macrocarpa. Extracts and selected pure compounds isolated from the leaves, roots, and stem bark showed antibacterial, antiviral, antiparasitic, anti-inflammatory, and cytotoxic activities in vitro. The aim of this review is to summarize the available ethnobotanical, phytochemical, and pharmacological information about this traditional Amazonian medicinal tree, as well as to attract the attention of phytochemists and pharmacognosists to this potentially interesting source of ethnopharmaceuticals.

Citovat

MALANÍK, Milan; Jakub TREML; Veronika RJAŠKOVÁ; Karolína TÍŽKOVÁ; Petra KAUCKÁ; Ladislav KOKOŠKA; Peter KUBATKA a Karel ŠMEJKAL. Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity. Molecules. BASEL: MDPI, 2019, roč. 24, č. 12, 22 s. ISSN 1420-3049. Dostupné z: https://doi.org/10.3390/molecules24122288.

@article{1726940,
   author = {Malaník, Milan and Treml, Jakub and Rjašková, Veronika and Tížková, Karolína and Kaucká, Petra and Kokoška, Ladislav and Kubatka, Peter and Šmejkal, Karel},
   article_location = {BASEL},
   article_number = {12},
   doi = {https://doi.org/10.3390/molecules24122288},
   keywords = {dihydro-beta-agarofuran sesquiterpene; folk medicine; Maytenus macrocarpa; rheumatism; triterpene},
   language = {eng},
   issn = {1420-3049},
   journal = {Molecules},
   title = {Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity},
   volume = {24},
   year = {2019}
}

TY  - JOUR
ID  - 1726940
AU  - Malaník, Milan - Treml, Jakub - Rjašková, Veronika - Tížková, Karolína - Kaucká, Petra - Kokoška, Ladislav - Kubatka, Peter - Šmejkal, Karel
PY  - 2019
TI  - Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity
JF  - Molecules
VL  - 24
IS  - 12
PB  - MDPI
SN  - 14203049
KW  - dihydro-beta-agarofuran sesquiterpene
KW  - folk medicine
KW  - Maytenus macrocarpa
KW  - rheumatism
KW  - triterpene
N2  - Maytenus macrocarpa (Celastraceae) is a tree native to Amazonia. Its roots, leaves, bark, and combinations of these are used in traditional medicine mainly to treat rheumatism and, to a lesser extent, to heal wounds and to combat bronchitis and diarrhea. To date, mainly triterpenes and dihydro-beta-agarofuran sesquiterpenes were isolated from M. macrocarpa. Extracts and selected pure compounds isolated from the leaves, roots, and stem bark showed antibacterial, antiviral, antiparasitic, anti-inflammatory, and cytotoxic activities in vitro. The aim of this review is to summarize the available ethnobotanical, phytochemical, and pharmacological information about this traditional Amazonian medicinal tree, as well as to attract the attention of phytochemists and pharmacognosists to this potentially interesting source of ethnopharmaceuticals.
ER  -

MALANÍK, Milan; Jakub TREML; Veronika RJAŠKOVÁ; Karolína TÍŽKOVÁ; Petra KAUCKÁ; Ladislav KOKOŠKA; Peter KUBATKA a Karel ŠMEJKAL. Maytenus macrocarpa (Ruiz \&{}amp; Pav.) Briq.: Phytochemistry and Pharmacological Activity. \textit{Molecules}. BASEL: MDPI, 2019, roč.~24, č.~12, 22 s. ISSN~1420-3049. Dostupné z: https://doi.org/10.3390/molecules24122288.

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