The metabolic profile of essential oils and assessment of
anti-urease activity by ESI-mass spectrometry of Salvia
officinalis L.

J 2019

The metabolic profile of essential oils and assessment of anti-urease activity by ESI-mass spectrometry of Salvia officinalis L.

HASSAN, STS.; Emil ŠVAJDLENKA; KRR. RENGASAMY; R. MELICHARKOVA; SK. PANDIAN et al.

Základní údaje

Originální název

The metabolic profile of essential oils and assessment of anti-urease activity by ESI-mass spectrometry of Salvia officinalis L.

Autoři

HASSAN, STS.; Emil ŠVAJDLENKA; KRR. RENGASAMY; R. MELICHARKOVA a SK. PANDIAN

Vydání

SOUTH AFRICAN JOURNAL OF BOTANY, AMSTERDAM, ELSEVIER SCIENCE BV, 2019, 0254-6299

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.792

Označené pro přenos do RIV

DOI

https://doi.org/10.1016/j.sajb.2018.04.023

UT WoS

000456314600022

Klíčová slova anglicky

Anti-urease activity; Antibacterial agent; Chemotype; Essential oils composition; Phenolic content; Salvia officinalis L.

Změněno: 24. 2. 2021 14:18, PharmDr. Jitka Michlíčková

Anotace

V originále

For decades, the therapeutic benefits of medicinal plants and their biologically active constituents have been well documented. In this study, the metabolic profile of Egyptian Salvia officinalis essential oils using Gas Chromatography (GC) and Gas Chromatography-Mass Spectrometry (GC-MS), total phenolic content (TPC) and anti-enzymatic properties of aqueous extract of S. officinalis (AESO) against jack bean urease (JBU) by an Electrospray Ionization-Mass Spectrometry (ESI-MS) were investigated. The results revealed that the primary metabolites detected in Salvia essential oils were 1,8-cineole (15.4%), oxygenated sesquiterpene viridiflorol (7.1%), nonacosane (3.1%), camphor (3.0%), and pentacosane (2.4%). The TPC content was determined to be 37.1 mg GAE/g dry plant material, while AESO exerted for the first time, anti-JBU with an IC50 value of 1.65 mg/mL. This study presents phenolic-rich AESO as a promising curative agent in the development of urease inhibitors useful to treat diseases induced by urease-producing pathogens. (c) 2018 SAAB. Published by Elsevier B.V. All rights reserved.

Citovat

HASSAN, STS.; Emil ŠVAJDLENKA; KRR. RENGASAMY; R. MELICHARKOVA a SK. PANDIAN. The metabolic profile of essential oils and assessment of anti-urease activity by ESI-mass spectrometry of Salvia officinalis L. SOUTH AFRICAN JOURNAL OF BOTANY. AMSTERDAM: ELSEVIER SCIENCE BV, 2019, roč. 120, s. 175-178. ISSN 0254-6299. Dostupné z: https://doi.org/10.1016/j.sajb.2018.04.023.

@article{1727196,
   author = {Hassan, STS. and Švajdlenka, Emil and Rengasamy, KRR. and Melicharkova, R. and Pandian, SK.},
   article_location = {AMSTERDAM},
   doi = {https://doi.org/10.1016/j.sajb.2018.04.023},
   keywords = {Anti-urease activity; Antibacterial agent; Chemotype; Essential oils composition; Phenolic content; Salvia officinalis L.},
   language = {eng},
   issn = {0254-6299},
   journal = {SOUTH AFRICAN JOURNAL OF BOTANY},
   title = {The metabolic profile of essential oils and assessment of anti-urease activity by ESI-mass spectrometry of Salvia officinalis L.},
   volume = {120},
   year = {2019}
}

TY  - JOUR
ID  - 1727196
AU  - Hassan, STS. - Švajdlenka, Emil - Rengasamy, KRR. - Melicharkova, R. - Pandian, SK.
PY  - 2019
TI  - The metabolic profile of essential oils and assessment of anti-urease activity by ESI-mass spectrometry of Salvia officinalis L.
JF  - SOUTH AFRICAN JOURNAL OF BOTANY
VL  - 120
SP  - 175-178
EP  - 175-178
PB  - ELSEVIER SCIENCE BV
SN  - 02546299
KW  - Anti-urease activity
KW  - Antibacterial agent
KW  - Chemotype
KW  - Essential oils composition
KW  - Phenolic content
KW  - Salvia officinalis L.
N2  - For decades, the therapeutic benefits of medicinal plants and their biologically active constituents have been well documented. In this study, the metabolic profile of Egyptian Salvia officinalis essential oils using Gas Chromatography (GC) and Gas Chromatography-Mass Spectrometry (GC-MS), total phenolic content (TPC) and anti-enzymatic properties of aqueous extract of S. officinalis (AESO) against jack bean urease (JBU) by an Electrospray Ionization-Mass Spectrometry (ESI-MS) were investigated. The results revealed that the primary metabolites detected in Salvia essential oils were 1,8-cineole (15.4%), oxygenated sesquiterpene viridiflorol (7.1%), nonacosane (3.1%), camphor (3.0%), and pentacosane (2.4%). The TPC content was determined to be 37.1 mg GAE/g dry plant material, while AESO exerted for the first time, anti-JBU with an IC50 value of 1.65 mg/mL. This study presents phenolic-rich AESO as a promising curative agent in the development of urease inhibitors useful to treat diseases induced by urease-producing pathogens. (c) 2018 SAAB. Published by Elsevier B.V. All rights reserved.
ER  -

HASSAN, STS.; Emil ŠVAJDLENKA; KRR. RENGASAMY; R. MELICHARKOVA a SK. PANDIAN. The metabolic profile of essential oils and assessment of anti-urease activity by ESI-mass spectrometry of Salvia officinalis L. \textit{SOUTH AFRICAN JOURNAL OF BOTANY}. AMSTERDAM: ELSEVIER SCIENCE BV, 2019, roč.~120, s.~175-178. ISSN~0254-6299. Dostupné z: https://doi.org/10.1016/j.sajb.2018.04.023.

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