Psoas density - an optimal sarcopaenic indicator associated with postoperative complications after colorectal resection for cancer?

PEKAŘOVÁ, Anna, Matej PEKAŘ, Marek SOLTES, Lucia HAVRLENTOVA and Tereza CHOVANCOVA. Psoas density - an optimal sarcopaenic indicator associated with postoperative complications after colorectal resection for cancer? VIDEOSURGERY AND OTHER MINIINVASIVE TECHNIQUES. POZNAN: TERMEDIA PUBLISHING HOUSE LTD, 2021, vol. 16, No 1, p. 91-97. ISSN 1895-4588. Available from: https://dx.doi.org/10.5114/wiitm.2020.100880.

Basic information

• Original name: Psoas density - an optimal sarcopaenic indicator associated with postoperative complications after colorectal resection for cancer?
• Authors: PEKAŘOVÁ, Anna (203 Czech Republic, guarantor, belonging to the institution), Matej PEKAŘ (703 Slovakia, belonging to the institution), Marek SOLTES (703 Slovakia), Lucia HAVRLENTOVA (203 Czech Republic) and Tereza CHOVANCOVA (203 Czech Republic).
• Edition: VIDEOSURGERY AND OTHER MINIINVASIVE TECHNIQUES, POZNAN, TERMEDIA PUBLISHING HOUSE LTD, 2021, 1895-4588.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30212 Surgery
• Country of publisher: Poland
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 1.627
• RIV identification code: RIV/00216224:14110/21:00120956
• Organization unit: Faculty of Medicine
• Doi: http://dx.doi.org/10.5114/wiitm.2020.100880
• UT WoS: 000624132700012
• Keywords in English: complications; colorectal cancer; computed tomography; sarcopaenia; psoas density
• Tags: 14110515, rivok
• Tags: International impact, Reviewed

Abstract

Introduction: Sarcopaenia seems to be predictive factor for postoperative morbidity and mortality after colorectal resection for cancer. Nevertheless, an ideal sarcopaenic indicator is still to be identified. Aim: To evaluate computed tomography (CT) measured total abdominal muscle area (TAMA), total psoas muscle area (TPA), and psoas density (PD) – previously described sarcopaenia indicators – as possible risk factors for postop- erative complications in patients after curative colon and rectal resections for colorectal cancer. Material and methods: Consecutive patients after elective curative colon or rectal resection for cancer at a sin- gle institution were divided into cohorts with uncomplicated postoperative course or complications Clavien-Dindo grade I-II (Cl-Di 0-II) and complications Clavien-Dindo grade III-V (Cl-Di III-V). Cohorts were statistically tested for significant differences in TAMA, TPA, and PD calculated from preoperative staging CT scans at the level of the third lumbar vertebra. Results: Data of 112 patients were analysed from a prospectively run database; 65 underwent colon and 47 rectal resections. PD was significantly higher in the Cl-Di 0-II cohort compared to the Cl-Di III-V for both colon (42.67 ±6.52 vs. 40.11 ±7.57 HU, p = 0.002) and rectal resections (44.08 ±5.86 vs. 43.03 ±5.70HU, p = 0.016). TAMA and TPA failed to show significant differences. Conclusions: Psoas density is significantly decreased in patients with Clavien-Dindo grade III-V complications after curative resection for colon and rectal cancer. Due to the simplicity and affordability of its assessment from preop- erative staging CT scan, it might be considered an optimal sarcopaenic indicator to be utilised in everyday practice.

Links

• MUNI/A/1307/2019, interní kód MU: Name: Kardiovaskulární systém od A do Z (Acronym: KAVASAZ)

Investor: Masaryk University, Category A