Associating physiological functions with genomic variability in
hibernating bats

J 2021

Associating physiological functions with genomic variability in hibernating bats

HARAZIM, Markéta; Lubomír PIÁLEK; Jiri PIKULA; Veronika SEIDLOVÁ; Jan ZUKAL et al.

Základní údaje

Originální název

Associating physiological functions with genomic variability in hibernating bats

Autoři

HARAZIM, Markéta; Lubomír PIÁLEK; Jiri PIKULA; Veronika SEIDLOVÁ; Jan ZUKAL; Erik BACHOREC; Tomáš BARTONIČKA; Tomasz KOKUREWICZ a Natália MARTÍNKOVÁ

Vydání

Evolutionary Ecology, Springer, 2021, 0269-7653

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.074

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/21:00121008

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

Genome-wide associations; ddRAD sequencing; Hibernation; Energy metabolism; Adaptation

Štítky

14314020, 143180, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 20. 2. 2023 11:05, doc. Mgr. Natália Martínková, Ph.D.

Anotace

V originále

The challenges of surviving periods of increased physiological stress elicit selective pressures that drive adaptations to overcome hardships. Bats in the Palearctic region survive winter in hibernation. We sampled single nucleotide polymorphisms (SNPs) in hibernating Myotis myotis bats using double-digest restriction site-associated DNA sequencing and we associated the genomic variability with the observed phenotypes reflecting hibernation site preference, body condition and bat health during hibernation. We did not observe genotype associations between the detrended body condition index, representing fat reserves, and functional genes involved in fat metabolism. Bat body surface temperature, reflecting roost selection, or roost warmth relative to the climate at the site did not show any associations with the sampled genotypes. We found SNPs with associations to macroclimatic variables, characterising the hibernaculum, and blood biochemistry, related to health of the bat. The genes in proximity of the associated SNPs were involved in metabolism, immune response and signal transduction, including chaperones, apoptosis and autophagy regulators and immune signalling molecules. The genetic adaptations included adaptation to tissue repair and protection against tissue damage.

Návaznosti

LM2018140, projekt VaV

Název: e-Infrastruktura CZ (Akronym: e-INFRA CZ)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, e-Infrastruktura CZ

MUNI/A/1098/2019, interní kód MU

Název: Výzkum Ekologických a Evolučních Principů na modelu obratlovců a jejich parazitů

Investor: Masarykova univerzita, Výzkum Ekologických a Evolučních Principů na modelu obratlovců a jejich parazitů, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

HARAZIM, Markéta; Lubomír PIÁLEK; Jiri PIKULA; Veronika SEIDLOVÁ; Jan ZUKAL; Erik BACHOREC; Tomáš BARTONIČKA; Tomasz KOKUREWICZ a Natália MARTÍNKOVÁ. Associating physiological functions with genomic variability in hibernating bats. Evolutionary Ecology. Springer, 2021, roč. 35, č. 2, s. 291-308. ISSN 0269-7653. Dostupné z: https://doi.org/10.1007/s10682-020-10096-4.

@article{1731983,
   author = {Harazim, Markéta and Piálek, Lubomír and Pikula, Jiri and Seidlová, Veronika and Zukal, Jan and Bachorec, Erik and Bartonička, Tomáš and Kokurewicz, Tomasz and Martínková, Natália},
   article_number = {2},
   doi = {https://doi.org/10.1007/s10682-020-10096-4},
   keywords = {Genome-wide associations; ddRAD sequencing; Hibernation; Energy metabolism; Adaptation},
   language = {eng},
   issn = {0269-7653},
   journal = {Evolutionary Ecology},
   title = {Associating physiological functions with genomic variability in hibernating bats},
   url = {https://doi.org/10.1007/s10682-020-10096-4},
   volume = {35},
   year = {2021}
}

TY  - JOUR
ID  - 1731983
AU  - Harazim, Markéta - Piálek, Lubomír - Pikula, Jiri - Seidlová, Veronika - Zukal, Jan - Bachorec, Erik - Bartonička, Tomáš - Kokurewicz, Tomasz - Martínková, Natália
PY  - 2021
TI  - Associating physiological functions with genomic variability in hibernating bats
JF  - Evolutionary Ecology
VL  - 35
IS  - 2
SP  - 291-308
EP  - 291-308
PB  - Springer
SN  - 02697653
KW  - Genome-wide associations
KW  - ddRAD sequencing
KW  - Hibernation
KW  - Energy metabolism
KW  - Adaptation
UR  - https://doi.org/10.1007/s10682-020-10096-4
L2  - https://doi.org/10.1007/s10682-020-10096-4
N2  - The challenges of surviving periods of increased physiological stress elicit selective pressures that drive adaptations to overcome hardships. Bats in the Palearctic region survive winter in hibernation. We sampled single nucleotide polymorphisms (SNPs) in hibernating Myotis myotis bats using double-digest restriction site-associated DNA sequencing and we associated the genomic variability with the observed phenotypes reflecting hibernation site preference, body condition and bat health during hibernation. We did not observe genotype associations between the detrended body condition index, representing fat reserves, and functional genes involved in fat metabolism. Bat body surface temperature, reflecting roost selection, or roost warmth relative to the climate at the site did not show any associations with the sampled genotypes. We found SNPs with associations to macroclimatic variables, characterising the hibernaculum, and blood biochemistry, related to health of the bat. The genes in proximity of the associated SNPs were involved in metabolism, immune response and signal transduction, including chaperones, apoptosis and autophagy regulators and immune signalling molecules. The genetic adaptations included adaptation to tissue repair and protection against tissue damage.
ER  -

HARAZIM, Markéta; Lubomír PIÁLEK; Jiri PIKULA; Veronika SEIDLOVÁ; Jan ZUKAL; Erik BACHOREC; Tomáš BARTONIČKA; Tomasz KOKUREWICZ a Natália MARTÍNKOVÁ. Associating physiological functions with genomic variability in hibernating bats. \textit{Evolutionary Ecology}. Springer, 2021, roč.~35, č.~2, s.~291-308. ISSN~0269-7653. Dostupné z: https://doi.org/10.1007/s10682-020-10096-4.

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