Letter to the Editor: Significant mutation enrichment in
inverted repeat sites of new SARS-CoV-2 strains

J 2021

Letter to the Editor: Significant mutation enrichment in inverted repeat sites of new SARS-CoV-2 strains

BARTAS, Martin; Pratik GOSWAMI; Matej LEXA; Jiří ČERVEŇ; Adriana VOLNÁ et al.

Základní údaje

Originální název

Letter to the Editor: Significant mutation enrichment in inverted repeat sites of new SARS-CoV-2 strains

Autoři

BARTAS, Martin; Pratik GOSWAMI; Matej LEXA; Jiří ČERVEŇ; Adriana VOLNÁ; Miroslav FOJTA; Vaclav BRAZDA a Petr PEČINKA

Vydání

Briefings in Bioinformatics, Oxford University Press, 2021, 1467-5463

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10603 Genetics and heredity

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 13.994

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/21:00121296

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

SARS-CoV-2; mutations; inverted repeats

Štítky

143160, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 24. 10. 2023 21:22, doc. Ing. Matej Lexa, Ph.D.

Anotace

V originále

In a recently published paper, we have found that SARS-CoV-2 hot-spot mutations are significantly associated with inverted repeat loci and CG dinucleotides (Goswami, Bartas et al., 2020). However, fast-spreading strains with new mutations (so-called mink farm mutations, England mutations, and Japan mutations) have been recently described. We used the new datasets to check the positioning of mutation sites in genomes of the new SARS-CoV-2 strains. Using an open-access Palindrome analyzer tool we found mutations in these new strains to be significantly enriched in inverted repeat loci.

Citovat

BARTAS, Martin; Pratik GOSWAMI; Matej LEXA; Jiří ČERVEŇ; Adriana VOLNÁ; Miroslav FOJTA; Vaclav BRAZDA a Petr PEČINKA. Letter to the Editor: Significant mutation enrichment in inverted repeat sites of new SARS-CoV-2 strains. Briefings in Bioinformatics. Oxford University Press, 2021, roč. 22, č. 5, s. "bbab129", 17 s. ISSN 1467-5463. Dostupné z: https://doi.org/10.1093/bib/bbab129.

@article{1755027,
   author = {Bartas, Martin and Goswami, Pratik and Lexa, Matej and Červeň, Jiří and Volná, Adriana and Fojta, Miroslav and Brazda, Vaclav and Pečinka, Petr},
   article_number = {5},
   doi = {https://doi.org/10.1093/bib/bbab129},
   keywords = {SARS-CoV-2; mutations; inverted repeats},
   language = {eng},
   issn = {1467-5463},
   journal = {Briefings in Bioinformatics},
   title = {Letter to the Editor: Significant mutation enrichment in inverted repeat sites of new SARS-CoV-2 strains},
   url = {https://doi.org/10.1093/bib/bbab129},
   volume = {22},
   year = {2021}
}

TY  - JOUR
ID  - 1755027
AU  - Bartas, Martin - Goswami, Pratik - Lexa, Matej - Červeň, Jiří - Volná, Adriana - Fojta, Miroslav - Brazda, Vaclav - Pečinka, Petr
PY  - 2021
TI  - Letter to the Editor: Significant mutation enrichment in inverted repeat sites of new SARS-CoV-2 strains
JF  - Briefings in Bioinformatics
VL  - 22
IS  - 5
SP  - "bbab129"
EP  - "bbab129"
PB  - Oxford University Press
SN  - 14675463
KW  - SARS-CoV-2
KW  - mutations
KW  - inverted repeats
UR  - https://doi.org/10.1093/bib/bbab129
N2  - In a recently published paper, we have found that SARS-CoV-2 hot-spot mutations are significantly associated with inverted repeat loci and CG dinucleotides (Goswami, Bartas et al., 2020). However, fast-spreading strains with new mutations (so-called mink farm mutations, England mutations, and Japan mutations) have been recently described. We used the new datasets to check the positioning of mutation sites in genomes of the new SARS-CoV-2 strains. Using an open-access Palindrome analyzer tool we found mutations in these new strains to be significantly enriched in inverted repeat loci.
ER  -

BARTAS, Martin; Pratik GOSWAMI; Matej LEXA; Jiří ČERVEŇ; Adriana VOLNÁ; Miroslav FOJTA; Vaclav BRAZDA a Petr PEČINKA. Letter to the Editor: Significant mutation enrichment in inverted repeat sites of new SARS-CoV-2 strains. \textit{Briefings in Bioinformatics}. Oxford University Press, 2021, roč.~22, č.~5, s.~''bbab129'', 17 s. ISSN~1467-5463. Dostupné z: https://doi.org/10.1093/bib/bbab129.

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