Response to Vagal Stimulation by Heart-rate Features in
Drug-resistant Epileptic Patients

D 2020

Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients

PLESINGER, F.; J. HALAMEK; Jan CHLÁDEK; P. JURAK; Irena DOLEŽALOVÁ et al.

Základní údaje

Originální název

Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients

Autoři

PLESINGER, F.; J. HALAMEK; Jan CHLÁDEK; P. JURAK; Irena DOLEŽALOVÁ; Jan CHRASTINA a Milan BRÁZDIL

Vydání

NEW YORK, 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), od s. 46-49, 4 s. 2020

Nakladatel

IEEE

Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Obor

30210 Clinical neurology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

elektronická verze "online"

Odkazy

URL

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/20:00118651

Organizační jednotka

Lékařská fakulta

ISBN

978-1-7281-1990-8

ISSN

Klíčová slova anglicky

Vagal Stimulation; Heart-rate Features;Drug-resistant Epileptic Patients

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 7. 4. 2021 10:06, Mgr. Tereza Miškechová

Anotace

V originále

Vagal Nerve Stimulation (VNS) is an option in the treatment of drug-resistant epilepsy. However, approximately a quarter of VNS subjects does not respond to the therapy. In this retrospective study, we introduce heart-rate features to distinguish VNS responders and non-responders. Standard pre-implantation measurements of 66 patients were segmented in relation to specific stimuli (open/close eyes, photic stimulation, hyperventilation, and rests between). Median interbeat intervals were found for each segment and normalized (NMRR). Five NMRRs were significant; the strongest feature achieved significance with p=0.013 and AUC=0.66. Low mutual correlation and independence on EEG signals mean that presented features could be considered as an addition for models predicting VNS response using EEG.

Návaznosti

NV19-04-00343, projekt VaV

Název: Predikce Efektu Stimulace u pacientů s Epilepsií (PRESEnCE) (Akronym: PRESEnCE)

Investor: Ministerstvo zdravotnictví ČR, Prediction of Stimulation Efficacy in Epilepsy

Citovat

PLESINGER, F.; J. HALAMEK; Jan CHLÁDEK; P. JURAK; Irena DOLEŽALOVÁ; Jan CHRASTINA a Milan BRÁZDIL. Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients. Online. In 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). NEW YORK: IEEE, 2020, s. 46-49. ISBN 978-1-7281-1990-8. Dostupné z: https://doi.org/10.1109/EMBC44109.2020.9176326.

@inproceedings{1758038,
   author = {Plesinger, F. and Halamek, J. and Chládek, Jan and Jurak, P. and Doležalová, Irena and Chrastina, Jan and Brázdil, Milan},
   address = {NEW YORK},
   booktitle = {2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)},
   doi = {https://doi.org/10.1109/EMBC44109.2020.9176326},
   keywords = {Vagal Stimulation; Heart-rate Features;Drug-resistant Epileptic Patients},
   howpublished = {elektronická verze "online"},
   language = {eng},
   location = {NEW YORK},
   isbn = {978-1-7281-1990-8},
   pages = {46-49},
   publisher = {IEEE},
   title = {Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients},
   url = {https://ieeexplore.ieee.org/document/9176326/keywords#keywords},
   year = {2020}
}

TY  - CONF
ID  - 1758038
AU  - Plesinger, F. - Halamek, J. - Chládek, Jan - Jurak, P. - Doležalová, Irena - Chrastina, Jan - Brázdil, Milan
PY  - 2020
TI  - Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients
PB  - IEEE
CY  - NEW YORK
SN  - 9781728119908
KW  - Vagal Stimulation
KW  - Heart-rate Features;Drug-resistant Epileptic Patients
UR  - https://ieeexplore.ieee.org/document/9176326/keywords#keywords
N2  - Vagal Nerve Stimulation (VNS) is an option in the treatment of drug-resistant epilepsy. However, approximately a quarter of VNS subjects does not respond to the therapy. In this retrospective study, we introduce heart-rate features to distinguish VNS responders and non-responders. Standard pre-implantation measurements of 66 patients were segmented in relation to specific stimuli (open/close eyes, photic stimulation, hyperventilation, and rests between). Median interbeat intervals were found for each segment and normalized (NMRR). Five NMRRs were significant; the strongest feature achieved significance with p=0.013 and AUC=0.66. Low mutual correlation and independence on EEG signals mean that presented features could be considered as an addition for models predicting VNS response using EEG.
ER  -

PLESINGER, F.; J. HALAMEK; Jan CHLÁDEK; P. JURAK; Irena DOLEŽALOVÁ; Jan CHRASTINA a Milan BRÁZDIL. Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients. Online. In \textit{2020 42nd Annual International Conference of the IEEE Engineering in Medicine \&{} Biology Society (EMBC)}. NEW YORK: IEEE, 2020, s.~46-49. ISBN~978-1-7281-1990-8. Dostupné z: https://doi.org/10.1109/EMBC44109.2020.9176326.

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