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@inproceedings{1758038,
author = {Plesinger, F. and Halamek, J. and Chládek, Jan and Jurak, P. and Doležalová, Irena and Chrastina, Jan and Brázdil, Milan},
address = {NEW YORK},
booktitle = {2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)},
doi = {http://dx.doi.org/10.1109/EMBC44109.2020.9176326},
keywords = {Vagal Stimulation; Heart-rate Features;Drug-resistant Epileptic Patients},
howpublished = {elektronická verze "online"},
language = {eng},
location = {NEW YORK},
isbn = {978-1-7281-1990-8},
pages = {46-49},
publisher = {IEEE},
title = {Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients},
url = {https://ieeexplore.ieee.org/document/9176326/keywords#keywords},
year = {2020}
}
TY - JOUR
ID - 1758038
AU - Plesinger, F. - Halamek, J. - Chládek, Jan - Jurak, P. - Doležalová, Irena - Chrastina, Jan - Brázdil, Milan
PY - 2020
TI - Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients
PB - IEEE
CY - NEW YORK
SN - 9781728119908
KW - Vagal Stimulation
KW - Heart-rate Features;Drug-resistant Epileptic Patients
UR - https://ieeexplore.ieee.org/document/9176326/keywords#keywords
N2 - Vagal Nerve Stimulation (VNS) is an option in the treatment of drug-resistant epilepsy. However, approximately a quarter of VNS subjects does not respond to the therapy. In this retrospective study, we introduce heart-rate features to distinguish VNS responders and non-responders. Standard pre-implantation measurements of 66 patients were segmented in relation to specific stimuli (open/close eyes, photic stimulation, hyperventilation, and rests between). Median interbeat intervals were found for each segment and normalized (NMRR). Five NMRRs were significant; the strongest feature achieved significance with p=0.013 and AUC=0.66. Low mutual correlation and independence on EEG signals mean that presented features could be considered as an addition for models predicting VNS response using EEG.
ER -
PLESINGER, F., J. HALAMEK, Jan CHLÁDEK, P. JURAK, Irena DOLEŽALOVÁ, Jan CHRASTINA a Milan BRÁZDIL. Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients. Online. In \textit{2020 42nd Annual International Conference of the IEEE Engineering in Medicine \&{} Biology Society (EMBC)}. NEW YORK: IEEE, 2020, s.~46-49. ISBN~978-1-7281-1990-8. Dostupné z: https://dx.doi.org/10.1109/EMBC44109.2020.9176326.
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