Urine immunofixation negativity is not necessary for complete
response in intact immunoglobulin multiple myeloma:
Retrospective real-world confirmation

J 2021

Urine immunofixation negativity is not necessary for complete response in intact immunoglobulin multiple myeloma: Retrospective real-world confirmation

RADOCHA, Jakub; Tomas JELINEK; Luděk POUR; Ivan SPICKA; Jiri MINARIK et al.

Základní údaje

Originální název

Urine immunofixation negativity is not necessary for complete response in intact immunoglobulin multiple myeloma: Retrospective real-world confirmation

Autoři

Vydání

International Journal of Laboratory Hematology, MALDEN, WILEY-BLACKWELL, 2021, 1751-5521

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30205 Hematology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.453

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/21:00121704

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Urine immunofixation negativity; intact immunoglobulin multiple myeloma

Štítky

14110212, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 7. 12. 2021 13:49, Mgr. Tereza Miškechová

Anotace

V originále

The definition of complete disease response (CR) in multiple myeloma (MM) continues to be reevaluated. The last widely accepted model of response assessment was proposed by the International Myeloma Working Group (IMWG) in 2016.1 Urine immunofixation (uIFE), one of the CR parameters, is being frequently omitted from CR evaluation in routine clinical practice. Patients with missing uIFE are then reported as having very good partial response (VGPR).2 It has been recently suggested in retrospective analysis by Lahuerta et al3 that patients with intact immunoglobulin myeloma (IIMM) who lack uIFE examination present with the very same prognosis as the patients with negative uIFE and therefore uIFE might not be necessary for CR definition in such patients.

Citovat

RADOCHA, Jakub; Tomas JELINEK; Luděk POUR; Ivan SPICKA; Jiri MINARIK; Tereza POPKOVA; Alexandra JUNGOVA; Petr PAVLICEK; Lucie BROŽOVÁ; Martin ŠTORK; Frantisek SEDLAK; Petra KRHOVSKA; Vladimir MAISNAR; Adriana HEINDORFER; Michal SYKORA; Marek WROBEL; Peter MIKULA; Petr KESSLER; Jana ULLRYCHOVA a Roman HAJEK. Urine immunofixation negativity is not necessary for complete response in intact immunoglobulin multiple myeloma: Retrospective real-world confirmation. International Journal of Laboratory Hematology. MALDEN: WILEY-BLACKWELL, 2021, roč. 43, č. 5, s. "E244"-"E247", 4 s. ISSN 1751-5521. Dostupné z: https://doi.org/10.1111/ijlh.13460.

@article{1773329,
   author = {Radocha, Jakub and Jelinek, Tomas and Pour, Luděk and Spicka, Ivan and Minarik, Jiri and Popkova, Tereza and Jungova, Alexandra and Pavlicek, Petr and Brožová, Lucie and Štork, Martin and Sedlak, Frantisek and Krhovska, Petra and Maisnar, Vladimir and Heindorfer, Adriana and Sykora, Michal and Wrobel, Marek and Mikula, Peter and Kessler, Petr and Ullrychova, Jana and Hajek, Roman},
   article_location = {MALDEN},
   article_number = {5},
   doi = {https://doi.org/10.1111/ijlh.13460},
   keywords = {Urine immunofixation negativity; intact immunoglobulin multiple myeloma},
   language = {eng},
   issn = {1751-5521},
   journal = {International Journal of Laboratory Hematology},
   title = {Urine immunofixation negativity is not necessary for complete response in intact immunoglobulin multiple myeloma: Retrospective real-world confirmation},
   url = {https://onlinelibrary.wiley.com/doi/10.1111/ijlh.13460},
   volume = {43},
   year = {2021}
}

TY  - JOUR
ID  - 1773329
AU  - Radocha, Jakub - Jelinek, Tomas - Pour, Luděk - Spicka, Ivan - Minarik, Jiri - Popkova, Tereza - Jungova, Alexandra - Pavlicek, Petr - Brožová, Lucie - Štork, Martin - Sedlak, Frantisek - Krhovska, Petra - Maisnar, Vladimir - Heindorfer, Adriana - Sykora, Michal - Wrobel, Marek - Mikula, Peter - Kessler, Petr - Ullrychova, Jana - Hajek, Roman
PY  - 2021
TI  - Urine immunofixation negativity is not necessary for complete response in intact immunoglobulin multiple myeloma: Retrospective real-world confirmation
JF  - International Journal of Laboratory Hematology
VL  - 43
IS  - 5
SP  - "E244"-"E247"
EP  - "E244"-"E247"
PB  - WILEY-BLACKWELL
SN  - 17515521
KW  - Urine immunofixation negativity
KW  - intact immunoglobulin multiple myeloma
UR  - https://onlinelibrary.wiley.com/doi/10.1111/ijlh.13460
N2  - The definition of complete disease response (CR) in multiple myeloma (MM) continues to be reevaluated. The last widely accepted model of response assessment was proposed by the International Myeloma Working Group (IMWG) in 2016.1 Urine immunofixation (uIFE), one of the CR parameters, is being frequently omitted from CR evaluation in routine clinical practice. Patients with missing uIFE are then reported as having very good partial response (VGPR).2 It has been recently suggested in retrospective analysis by Lahuerta et al3 that patients with intact immunoglobulin myeloma (IIMM) who lack uIFE examination present with the very same prognosis as the patients with negative uIFE and therefore uIFE might not be necessary for CR definition in such patients.
ER  -

RADOCHA, Jakub; Tomas JELINEK; Luděk POUR; Ivan SPICKA; Jiri MINARIK; Tereza POPKOVA; Alexandra JUNGOVA; Petr PAVLICEK; Lucie BROŽOVÁ; Martin ŠTORK; Frantisek SEDLAK; Petra KRHOVSKA; Vladimir MAISNAR; Adriana HEINDORFER; Michal SYKORA; Marek WROBEL; Peter MIKULA; Petr KESSLER; Jana ULLRYCHOVA a Roman HAJEK. Urine immunofixation negativity is not necessary for complete response in intact immunoglobulin multiple myeloma: Retrospective real-world confirmation. \textit{International Journal of Laboratory Hematology}. MALDEN: WILEY-BLACKWELL, 2021, roč.~43, č.~5, s.~''E244''-''E247'', 4 s. ISSN~1751-5521. Dostupné z: https://doi.org/10.1111/ijlh.13460.

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